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Badreddin Edris

Director at Edgewise Therapeutics
Board

About Badreddin Edris, Ph.D.

Independent director since February 2021; age 37 as of March 31, 2025. Co‑founder of Edgewise Therapeutics; currently Chief Operating Officer at SpringWorks Therapeutics (since January 2021). Academic credentials include B.I.S. in microbiology (Weber State), M.S. in biology (Stanford), and Ph.D. in genetics (Stanford; NSF Graduate Research Fellow). Background spans operating roles and healthcare private equity at OrbiMed and strategic roles at Silverback Therapeutics and Bain & Co.

Past Roles

OrganizationRoleTenureCommittees/Impact
Edgewise Therapeutics (EWTX)Co‑founder; operational role; later advisorOperational role May 2017–Mar 2018; director since Feb 2021Founding perspective; transitioned to governance
OrbiMed Advisors LLCInvestment and operating professional (private equity team)Jun 2014–Nov 2018Deal execution, portfolio operations in biotech
Silverback Therapeutics, Inc.Head of Corporate Development; Chief Business OfficerApr 2016–Mar 2018; Apr–Sep 2018Company building; BD leadership at OrbiMed portfolio company
Bain & Co Inc.Management consultant (healthcare practice)Prior to OrbiMed (dates not specified)Strategy and operations projects in healthcare

External Roles

OrganizationRoleTenureCommittees/Impact
SpringWorks Therapeutics, Inc.Chief Operating Officer (previously Chief Business Officer)COO since Jan 2021; CBO Sep 2018–Dec 2020Commercial-stage rare disease and oncology operator
  • No other current public company directorships disclosed.

Board Governance

  • Independence: Board determined Dr. Edris is independent under Nasdaq rules; six of eight directors are independent.
  • Committee assignments: Compensation Committee Chair; not listed on Audit or Nominating & Corporate Governance.
  • Attendance: Each director attended at least 75% of board and applicable committee meetings in FY2024; board met four times; all directors attended the 2024 annual meeting.
  • Committee meeting cadence (2024): Audit 4; Compensation 2; Nominating & Corporate Governance 1.
  • Governance practices: Independent director executive sessions at each regular board meeting; formal clawback policy adopted Oct 2023; hedging and pledging of company stock prohibited.

Fixed Compensation (Director)

ComponentAmountNotes
Fees Earned or Paid in Cash (FY2024)$48,227Actual cash paid in FY2024 per Director Compensation Table
Policy—Annual Cash Retainer$40,000Effective Mar 2024 (from $38,000)
Policy—Compensation Committee Chair Fee$15,000Effective Jan 1, 2025 (from $10,000)

Performance Compensation (Director Equity)

ComponentFY2024 ValueVestingKey Terms
Option Awards (grant date fair value)$247,738Annual option grant vests in full on first anniversary of grant or immediately before next annual meeting10‑year term; exercise price = 100% FMV on grant; full acceleration upon change in control for non‑employee directors
  • Initial director equity award (policy): Option grant targeted at $700,000 grant date fair value (cap: 60,000 shares) for first‑time non‑employee directors; increased Jan 1, 2025. Annual award targeted at $350,000 (cap: 30,000 shares) starting Jan 1, 2025.
  • Change‑in‑control: Director equity fully accelerates if still serving at the transaction date.

Other Directorships & Interlocks

CategoryDetail
Compensation Committee InterlocksNone; no officers of EWTX serving on other boards’ comp committees, and comp committee members (including Dr. Edris) are not current or former officers/employees of EWTX per proxy disclosure.
Network tiesHistorical OrbiMed affiliation (private equity) and multiple OrbiMed ties at EWTX (e.g., Chair Peter Thompson is an OrbiMed Partner; OrbiMed is a 15.8% holder). Independence determinations and related‑party review processes are disclosed.

Expertise & Qualifications

  • Drug development and BD leadership across rare diseases/oncology; co‑founder perspective at Edgewise.
  • Private equity operating experience (OrbiMed) and healthcare consulting (Bain).
  • Technical training: microbiology (B.I.S.), biology (M.S.), genetics (Ph.D.), NSF Graduate Research Fellow.

Equity Ownership

MeasureAmountNotes
Total Beneficial Ownership (Mar 31, 2025)199,501 shares“*” <1% of outstanding shares
Directly Held Shares19,820As of Mar 31, 2025
Options Exercisable ≤60 days179,681As of Mar 31, 2025
Total Outstanding Director Options (Dec 31, 2024)200,275Aggregate options outstanding (not all exercisable within 60 days)
Hedging/PledgingProhibited by policy (limited exceptions require approvals)Alignment safeguard for directors and officers

Governance Assessment

  • Board effectiveness: As Compensation Committee Chair, Dr. Edris oversees executive/director pay philosophy, approves pay and administers equity plans; the committee met twice in 2024—appropriate for a clinical‑stage biotech cadence but worth monitoring as organization scales.
  • Independence and conflicts: Although historical OrbiMed ties exist within the board and cap table, the board affirmed Dr. Edris’s independence; related‑party transactions (e.g., shareholder participations in offerings) are overseen by the Audit Committee under a formal policy. No related‑party transactions disclosed involving Dr. Edris personally.
  • Compensation alignment: Director cash is modest vs. equity options—equity grants are time‑based (not performance‑based), with single‑trigger change‑in‑control acceleration; this is common in biotech but grants increased materially in 2025, elevating dilution risk and pay sensitivity to share price—monitor grant sizing vs. TSR.
  • Engagement: ≥75% attendance and regular independent director executive sessions support oversight quality; formal clawback and insider trading policies strengthen investor protections.

RED FLAGS to monitor

  • Single‑trigger equity acceleration for directors at change‑in‑control can misalign incentives in sale scenarios; consider investor pushback if grant sizes continue rising.
  • OrbiMed’s significant ownership and multiple ties at board level necessitate continued robust independence and related‑party oversight (currently disclosed and in place).

Signals supporting investor confidence

  • Independence affirmation; formal related‑party review policy; prohibition on hedging/pledging; clawback adoption; consistent attendance.