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George Poste

Independent Director at EXELIXISEXELIXIS
Board

About George Poste

George Poste, DVM, Ph.D., FRS, age 80, has served as an independent director at Exelixis since August 2004. He is Chief Scientist at the Complex Adaptive Systems Initiative and Regents’/Del E. Webb Professor of Health Innovation at Arizona State University since 2009, and previously directed ASU’s Biodesign Institute (2003–2009). He holds a DVM and Ph.D. in Virology from the University of Bristol, plus Board Certification in Pathology (Royal College of Pathologists), and is a Fellow of the Royal Society and UK Academy of Medical Sciences, among others .

Past Roles

OrganizationRoleTenureCommittees/Impact
SmithKline Beecham CorporationChief Science & Technology Officer; President, R&D1992–1999Led pharmaceutical R&D strategy
Biodesign Institute (ASU)Director2003–2009Built interdisciplinary biomedical research programs
Health Technology NetworksChief Executive OfficerSince 2000Consulting in genomics and computing in healthcare
U.S. Department of DefenseDefense Science Board member2001–2010National biodefense policy/advisory work

External Roles

OrganizationRoleTenureTypeNotes
Complex Adaptive Systems Initiative (ASU)Chief ScientistSince 2009AcademicRegents’/Del E. Webb Professor of Health Innovation
Caris Life SciencesDirectorSince 2009PrivateDiagnostics company board member
MediSix Therapeutics Pte. Ltd.DirectorSince 2022PrivateImmune engineering therapies
InanoBio, Inc.Director2021–2023PrivateBiotechnology board service
Monsanto CompanyDirector2003–2018PublicAcquisition by Bayer in 2018
Orchid Cellmark, Inc.Non-executive ChairmanUntil 2009PublicAcquisition by LabCorp in 2009

Board Governance

  • Committee assignments: Chair, Research & Development Committee; Member, Risk Committee; both composed entirely of independent directors .
  • Independence: Listed as “Independent Director” nominee; Board determined 10 of 11 nominees (excluding CEO) are independent .
  • Meetings/attendance: In fiscal 2024, Board held 7 meetings; committees held Audit 4, Compensation 6, Governance 5, R&D 4, Risk 2; all directors attended at least 75% of Board and committee meetings; independent directors held 4 executive sessions .
  • Term: Annual election of directors; one-year terms under Certificate of Incorporation and Bylaws .
FY2024 Meeting CountsBoardAuditCompensationGovernanceR&DRisk
Number of meetings7 4 6 5 4 2

Fixed Compensation

Component (FY2024)Amount (USD)Basis
Board retainer$60,000 Annual cash retainer for non-employee directors
R&D Committee membership$12,000 Annual cash retainer
R&D Committee chair$13,000 Additional annual cash retainer
Risk Committee membership$12,000 Annual cash retainer
Total cash paid (Poste)$97,000 Director Compensation Table (FY ended Jan 3, 2025)

Performance Compensation

Equity ElementGrant DateElection/MixGrant Date Fair Value (USD)VestingNotes
Annual RSU (Poste)May 31, 2024100% RSUs elected $408,596 100% on first anniversary of grant date Granted under 2017 Plan Directors’ Policy; value-based approach
Stock options (Poste, FY2024)No option award granted in FY2024
Change-in-control100% acceleration of unvested director equity; repurchase rights terminate Applies to non-employee director awards

Performance metrics tied to director compensation: None disclosed (director awards are time-based, not performance-based) .

Other Directorships & Interlocks

CategoryCompanyRoleOverlap/Interlock
Current public boardsNoneNone
Prior public boardsMonsanto CompanyDirector (2003–2018)Agriculture; no EXEL related-party transactions disclosed
Prior public boardsOrchid Cellmark, Inc.Non-executive Chairman (until 2009)DNA forensics; no EXEL related-party transactions disclosed
Private boardsCaris Life SciencesDirector (since 2009)Diagnostics; no EXEL related-party transactions disclosed
Private boardsMediSix TherapeuticsDirector (since 2022)Immune engineering; no EXEL related-party transactions disclosed

Expertise & Qualifications

  • Training and expertise: Scientist with deep life sciences, healthcare, and pharmaceutical knowledge; broad leadership from board service; policymaking/regulatory experience (e.g., DSB) .
  • Education: DVM (Veterinary Medicine) and Ph.D. (Virology) from University of Bristol; Board Certification in Pathology (Royal College of Pathologists) .
  • Recognition: Fellow of the Royal Society, UK Academy of Medical Sciences; honorary doctorates and affiliations at Hoover Institution, Stanford .

Equity Ownership

MetricValueNotes
Beneficially owned shares170,816 As of Feb 28, 2025
Beneficial ownership % of total* Percent not itemized; below reporting threshold indicated by *
Options exercisable within 60 days (of Feb 28, 2025)20,634 Footnote (14)
Total options outstanding (as of Jan 3, 2025)36,508 Aggregate options held
RSUs held (as of Jan 3, 2025)18,838 Aggregate RSUs held
Hedging/margin loansProhibited Insider trading policy
PledgingProhibited; none pledged by directors/executives as of proxy date
Ownership guideline5× annual cash Board retainer; all non-employee directors met targets as of Feb 28, 2025

Say-on-Pay & Election Results (2025 Annual Meeting)

ProposalForAgainstAbstainBroker Non-Votes
Election – George Poste222,946,800 2,868,484 183,168 23,953,528
Say on Pay (NEOs)218,948,303 6,761,611 288,538 23,953,528

Related-Party Transactions (Conflict Indicators)

  • Policy: Audit Committee reviews/approves related person transactions; formal policy in place .
  • FY2024 disclosure: No related party transactions reportable under SEC rules, other than BlackRock managing a portion of cash/investments and related fees; no director-related transactions reported .

Governance Assessment

  • Strengths: Long-tenured scientific leader; chairs R&D Committee aligning oversight with oncology pipeline strategy; serves on Risk Committee overseeing compliance, litigation, and cybersecurity; both committees are independent .
  • Attendance/engagement: Board/committee workload appears robust; all directors met ≥75% attendance; independent director executive sessions held 4 times in 2024 .
  • Alignment: Meaningful equity retainer via RSUs with time-based vesting; ownership guidelines met; no hedging/pledging permitted and none pledged; director compensation capped and benchmarked; no option repricing .
  • Shareholder confidence: Strong 2025 support for Poste’s re-election; Say-on-Pay approved comfortably, indicating stable governance sentiment .
  • RED FLAGS: None disclosed for related-party transactions, attendance shortfalls, pledging/hedging, or equity repricing; no public company interlocks currently (reduces conflict risk) .