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Mary C. Beckerle

Independent Director at EXELIXISEXELIXIS
Board

About Mary C. Beckerle

Mary C. Beckerle, Ph.D. (age 70) joined Exelixis’ Board in January 2024 and is an independent director with deep oncology leadership experience. She has served since 2006 as CEO of Huntsman Cancer Institute at the University of Utah, and is Associate Vice President for Cancer Affairs and a Distinguished Professor of Biology and Oncological Sciences; she first joined the University of Utah faculty in 1986. Dr. Beckerle holds a B.A. in Biology and Psychology from Wells College (magna cum laude), a Ph.D. in Molecular, Cellular and Developmental Biology from the University of Colorado Boulder, and completed post-doctoral work at UNC Chapel Hill . The Board determined she is independent under SEC and Nasdaq standards; 10 of 11 nominees are independent overall .

Past Roles

OrganizationRoleTenureCommittees/Impact
Huntsman Cancer Institute, University of UtahChief Executive Officer2006–presentLeads a world-class cancer center; also Associate VP for Cancer Affairs; Distinguished Professor; Jon M. Huntsman Presidential Endowed Chair
University of UtahFaculty (Biology/Oncological Sciences)1986–presentNumerous research and leadership roles
American Society for Cell BiologyPresident2006–2007Scientific leadership in cell biology
American Cancer SocietyCouncil for Extramural Grants2008–2012Chair 2010–2012
National Cancer InstituteBoard of Scientific Advisors2018–2022Scientific oversight and advice
Dana-Farber/Harvard Cancer CenterExternal Advisory Board2013–2022External scientific oversight
NIH Advisory Committee to the DirectorMember2007–2010; reappointed 2024High-level NIH advisory role

External Roles

OrganizationRoleTenureCommittees/Impact
Johnson & JohnsonDirector2015–presentScience & Technology Committee (Chair); Regulatory Compliance & Sustainability Committee
Huntsman CorporationDirector2011–presentNominating & Corporate Governance; Sustainability Committee
Howard Hughes Medical InstituteMedical Advisory Board member2015–presentScientific advisory role
National Academies and SocietiesMemberVariousElected to National Academy of Sciences, American Philosophical Society, American Academy of Arts and Sciences

Board Governance

  • Committee assignments: Nominating & Corporate Governance; Research & Development; Risk (appointed to Risk effective Jan 1, 2025) .
  • Independence: Determined independent; Board overall is 91% independent (10/11 nominees) .
  • Attendance and engagement: Board held seven meetings in 2024; all directors attended at least 75% of Board and committee meetings; independent directors met in four executive sessions .
  • Committee cadence (FY2024): Audit (4), Compensation (6), Governance (5), R&D (4), Risk (2) .
  • Leadership structure: Independent Chair of the Board (Stelios Papadopoulos); Chair role separated from CEO .
  • Stock ownership guidelines: Non-employee directors must hold 5x the annual cash Board retainer; as of Feb 28, 2025 all non-employee directors met the requirement .
  • Insider trading policy: Prohibits short sales, derivatives, hedging/monetization, margin purchases; updated Dec 2024 to prohibit pledging; no director/officer had pledged shares as of the proxy date .

Fixed Compensation

ComponentEXEL Director Program (2024)Notes
Board Annual Cash Retainer$60,000Paid quarterly in arrears
Additional Chair (Board)$35,000If serving as Chair
Audit Committee Member$15,000Chair add’l $15,000
Compensation Committee Member$12,000Chair add’l $13,000
Governance Committee Member$12,000Chair add’l $13,000
Research & Development Committee Member$12,000Chair add’l $13,000
Risk Committee Member$12,000Chair add’l $13,000
Mary C. Beckerle (FY2024)Amount ($)
Fees Earned or Paid in Cash$84,000
Total Cash Compensation$84,000
  • Context: The $84,000 cash reflects Board retainer ($60,000) plus two committee memberships in 2024 (Governance and R&D); Risk Committee membership began Jan 1, 2025 and did not contribute to 2024 cash .

Performance Compensation

Equity Award TypeGrant DateSharesGrant-Date Fair Value ($)Vesting/Terms
Initial RSUJan 5, 202415,424$358,45425% annually over 4 years; service-based
Initial Stock OptionJan 5, 202430,848$310,898Immediately exercisable; subject to company repurchase right; vests 25% at 1st anniversary, then monthly over next 3 years; strike = 100% FMV at grant; post-termination exercise up to earlier of 3 years or remaining term (≤7 years)
Annual Director RSU (FY2024 cycle)May 31, 2024Not disclosed (see RSU holdings below)Included in Stock AwardsVests 100% at 1-year anniversary; she elected RSUs (not options) for annual award
  • Outstanding holdings: RSUs held as of Jan 3, 2025 = 34,262; options outstanding = 30,848 (director-level) .
  • Change-in-control: 100% of outstanding, unvested director equity immediately vests; repurchase rights terminate .
  • Director equity is time-based; there are no performance conditions tied to director grants . For company alignment context, the most important NEO pay-for-performance measures were Relative TSR and Net Product Revenues in 2024 .

Other Directorships & Interlocks

CompanySectorRoleCommittee Roles
Johnson & JohnsonDiversified healthcareDirectorScience & Technology (Chair); Regulatory Compliance & Sustainability
Huntsman CorporationSpecialty chemicalsDirectorNominating & Corporate Governance; Sustainability
  • Network considerations: Another EXEL director (Tomas J. Heyman) previously held senior roles at Johnson & Johnson (Corporate VC President; Global Head of BD); this creates a historical network tie that may facilitate industry insight but is not a disclosed related-party transaction .

Expertise & Qualifications

  • Oncology and translational science leader; decades of cancer research and treatment experience .
  • Recognitions: NACD Corporate Governance Fellow; 2018 NACD Directorship 100 honoree; elected member of NAS, APS, and AAAS .
  • Corporate governance: Extensive public company board service with committee leadership (J&J Science & Technology Chair) .

Equity Ownership

MeasureAmount
Beneficial Ownership (Shares)22,494; less than 1% (*)
Options Exercisable within 60 days (included above)22,494 (subject to repurchase if early exercised)
RSUs Outstanding (as of Jan 3, 2025)34,262
Director-level Options Outstanding30,848
Pledging/Hedging StatusCompany policy prohibits hedging and pledging; no director/officer pledges outstanding
Ownership Guideline ComplianceMet (≥5x annual cash Board retainer as of Feb 28, 2025)

() Percentage not stated; reported as “” in beneficial ownership table indicating less than 1% .

Governance Assessment

  • Strengths

    • Independent director with high relevant domain expertise (oncology) on R&D and Risk Committees; adds scientific rigor to oversight .
    • Robust attendance standard met by all directors; active executive sessions enhance independent oversight .
    • Strong alignment practices (director ownership guidelines; prohibition of hedging/pledging) reduce misalignment risks .
    • Director compensation is balanced and within shareholder-approved plan limits; value-based equity awards with clear vesting .
  • Potential watch items

    • External board at Johnson & Johnson could present perceived conflict if EXEL enters material transactions with J&J; Audit Committee reviews related-party transactions, and none were reported in 2024 beyond a BlackRock investment management relationship .
    • Change-in-control single-trigger vesting for director equity (accelerates on deal close) is common but can be seen as generous; investors often prefer double-trigger even for directors .
  • Compensation mix and signals

    • FY2024 cash $84,000 vs. equity grants totaling $1,077,948 in grant-date fair value (stock awards + options), indicating emphasis on equity alignment; total $1,161,948 .
    • Initial equity awards on appointment follow policy ($680,000 target value split option/RSU), plus annual RSU grant; vesting schedules are time-based (no performance conditions) .
  • Committee effectiveness and independence

    • Governance Committee responsibilities include board performance assessments, independence compliance, and CEO succession planning—areas where her governance experience is additive .
    • Risk Committee oversight spans compliance (cybersecurity, drug safety, healthcare compliance); medical/scientific background supports informed risk oversight .

No legal proceedings, related-party transactions involving Dr. Beckerle, or pledging/hedging red flags were disclosed for 2024 .

Director Compensation Detail (FY2024)

ItemAmount ($)
Fees Earned or Paid in Cash$84,000
Stock Awards (Grant-Date FV)$767,050
Option Awards (Grant-Date FV)$310,898
All Other Compensation
Total$1,161,948

Related-Party Transactions and Conflicts

  • Policy: Audit Committee reviews/approves related-person transactions; management must submit transactions for approval/ratification .
  • FY2024 disclosure: No related-party transactions reportable under SEC rules other than BlackRock managing a portion of cash/investments ($568.0m fair value at Jan 3, 2025; $0.3m fees in 2024) .
  • Compensation Committee interlocks: None; members were independent and no interlocking relationships existed in 2024 .

Say-on-Pay & Shareholder Engagement

  • Annual say-on-pay proposal presented; Board recommends approval .
  • Stockholder outreach: Bi-annual engagement targeting top 35 holders (>60% outstanding), 100% acceptance of requested meetings; feedback integrated into governance and compensation practices .

Compensation Structure and Policies (Context)

  • Director equity awards: Value-based approach; initial award ~$680,000; annual award ~$400,000; choice of RSUs vs. options; equitable vesting; change-in-control acceleration .
  • Plan limits: Director compensation caps $750,000/year after first year; $1,500,000 in the first calendar year of appointment; caps approved by shareholders .

Conclusion

Dr. Beckerle brings high-value scientific and governance expertise to EXEL’s Board and key committees, with compensation and ownership practices that align with shareholder interests. No conflicts or attendance issues were disclosed, and policies around ownership, hedging/pledging, and related-party oversight are robust, supporting investor confidence in board effectiveness .