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Fariborz Kamal

President and Chief Operating Officer at 4D Molecular Therapeutics
Executive

About Fariborz Kamal

Fariborz Kamal, Ph.D., age 62, is President and Chief Operating Officer of 4D Molecular Therapeutics (FDMT). He has served as President & COO since September 2022, previously COO from February 2020 to September 2022, and Chief Technical Officer from October 2018 to February 2020, reflecting a progression from technical leadership into enterprise operations . Dr. Kamal holds a B.S. in Chemistry (San Jose State University, 1986), an M.Sc. in Chemistry (The American University, 2000), and a Ph.D. in Chemistry (The American University, 2003), underpinning deep domain expertise in quality and regulatory CMC for advanced therapeutics . 2024 incentives were paid at 75% of target based on corporate and individual performance assessment, indicating partial attainment of annual operational milestones .

Past Roles

OrganizationRoleYearsStrategic Impact
4D Molecular TherapeuticsPresident & Chief Operating OfficerSep 2022 – PresentEnterprise operations leadership; accountable for corporate and individual performance objectives driving annual bonus outcomes
4D Molecular TherapeuticsChief Operating OfficerFeb 2020 – Sep 2022Built and scaled operations pre-commercial; bridged development-to-operations
4D Molecular TherapeuticsChief Technical OfficerOct 2018 – Feb 2020Led Quality/Regulatory CMC; foundational technical systems

External Roles

OrganizationRoleYearsStrategic Impact
AveXis Inc.SVP, Quality & Regulatory CMCMay 2017 – Aug 2018Quality/CMC leadership in gene therapy; late-stage CMC rigor
Juno TherapeuticsVP, QualityMay 2015 – Apr 2017Established cell therapy quality systems
Intermune Inc.VP, Quality & Regulatory CMCJan 2013 – Mar 2015Advanced regulatory CMC frameworks for biotech pipeline

Fixed Compensation

Metric20232024
Base Salary (paid) ($)489,389 546,273
Base Salary Rate ($)536,000 effective Feb 18, 2024 (prior $498,837)
Target Bonus (%)45% 45%
All Other Compensation ($)7,731 (cash paid in lieu of accrued/unused vacation tied to HR transition)
Total Compensation ($)4,544,260 734,607

Performance Compensation

Annual Cash Bonus (2024)

MetricWeightingTargetActualPayout ($)Vesting/Payment
Corporate performance90%100% of target75% achievementIncluded in $180,603 Non-Equity IncentivePaid early 2025
Individual performance10%DiscretionaryAssessed by BoardIncluded in $180,603 Non-Equity IncentivePaid early 2025
Target bonus45% of base salary

Notes: 2024 total bonus paid (non-equity incentive) to Kamal was $180,603; Board determined corporate achievement of 75% and applied weighting of 90% corporate/10% individual .

Equity Options (Grant Practices and 2023/2024 Snapshot)

AttributeDetails
Grant cadenceLarge 2023 Q4 grants intended to capture 2024 annual grants; no new NEO equity grants in 2024
Exercise price policyOptions granted at closing trading price on grant date
Vesting mechanicsMost options vest 1/48 monthly; certain grants vest 25% at 1-year then 1/48 monthly thereafter
2023 Kamal grant size260,000 options (Dec 11, 2023)

Equity Ownership & Alignment

Beneficial Ownership

As-of DateShares OwnedOptions/RSUs Exercisable Within 60 DaysTotal Beneficial Ownership% of Shares Outstanding
Apr 3, 20245,942 458,170 464,112 <1% (asterisk denotes <1%)
Apr 21, 20255,942 608,800 614,742 1.3% (outstanding shares 46,324,642)

Outstanding Options (as of Dec 31, 2024)

Vesting Commencement DateExercisable (#)Unexercisable (#)Strike ($)Expiration
10/12/2018214,887 0 8.27 10/11/2028
12/20/201871,930 0 8.27 12/19/2028
03/08/202156,250 3,750 41.66 03/07/2031
02/01/202249,583 20,417 15.78 01/31/2032
09/01/202233,750 26,250 8.04 08/31/2032
09/23/20228,437 6,563 8.06 09/22/2032
02/10/202334,375 40,625 20.24 02/09/2033
12/11/202365,000 195,000 14.42 12/10/2033

Vesting schedules: generally 1/48 monthly; 2018 grants and certain 2023 new-hire structures vest 25% at one year then monthly thereafter . Hedging transactions are prohibited by policy; no pledging policy disclosure found in proxy .

Employment Terms

ProvisionOutside CIC PeriodWithin CIC Period (Double Trigger: termination without cause/for good reason)
Cash severance9 months base salary (Kamal) 12 months base salary
Bonus treatmentPro-rated portion of target annual bonus at 100% assumption; plus any earned but unpaid prior-year bonus 12 months of target bonus plus pro-rated portion; plus any earned but unpaid prior-year bonus
COBRA9 months 12 months
Equity vestingFull acceleration for each equity award; performance-vesting governed by award agreements
ConditionsEffective release; compliance with confidentiality and non-disparagement obligations

Agreements are change-in-control severance agreements separate from offer letters; no non-compete/non-solicit specifics disclosed in proxy . Company adopted an exchange-act Rule 10D-1 clawback policy covering incentive-based compensation received on/after Oct 2, 2023 with recovery over three-year lookback upon restatement .

Compensation Structure Observations

  • Front-loaded equity: Committee granted large options in Q4 2023 intended to cover 2024 annual grants; no NEO equity grants in 2024, indicating emphasis on long-term equity alignment with monthly vesting cadence .
  • Pay mix shift YoY: 2023 compensation for Kamal was equity-heavy ($3.76m option grant-date fair value) versus 2024’s primarily cash mix (salary + $180,603 performance bonus), reducing near-term dilution but sustaining retention via 2023 grants .
  • Bonus mechanics emphasize corporate milestones: 2024 payout set at 75% achievement level, with 90% corporate weighting for Kamal, aligning cash incentives to program execution rather than financial metrics (consistent with clinical-stage profile) .

Related Party and Governance Considerations

  • Related party employment: Kamal’s son employed in IT; 2024 compensation ~$0.1m and granted RSUs/options with aggregate grant-date fair value ~$0.04m; transactions reviewed under related person policy (Audit Committee oversight) .
  • Hedging prohibition: Insider Trading Compliance Policy prohibits hedging (e.g., zero-cost collars, forward sale contracts) .
  • Stock ownership guidelines: No disclosure on executive ownership guidelines in the 2025 proxy; not found in 2024 proxy search either .

Investment Implications

  • Alignment: Kamal’s significant vested and unvested option holdings (614,742 beneficially owned with 608,800 exercisable within 60 days as of April 21, 2025) align incentives with equity value creation; monthly vesting across grants smooths vesting events, potentially diffusing episodic selling pressure .
  • Retention: Double-trigger CIC protections with full equity acceleration and 12 months base + COBRA are competitive but not excessive; outside CIC severance is nine months base + pro-rated bonus and COBRA, balancing retention with shareholder protections via clawback policy .
  • Governance risk: The familial employment is modest in scale and disclosed; hedging is prohibited, reducing misalignment risk; absence of disclosed pledging policy or ownership guidelines is a monitoring item rather than an immediate red flag .