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John Milligan

Executive Chairman at 4D Molecular Therapeutics
Board

About John F. Milligan, Ph.D.

John F. Milligan serves as Executive Chairman of 4D Molecular Therapeutics’ (FDMT) Board (Class III), age 64 as of April 29, 2025, and has been on the board since August 2020 . The Board has affirmatively determined he is an “independent” director under Nasdaq rules, even while serving as Executive Chairman . He earned a B.A. in Chemistry from Ohio Wesleyan University (1983) and a Ph.D. from the University of Illinois at Urbana‑Champaign (1988), and completed postdoctoral work at UCSF . As Executive Chairman, he presides over Board meetings and executive sessions and serves as liaison between management and the Board .

Past Roles

OrganizationRoleTenure (Dates)Committees/Impact
Gilead Sciences, Inc.President & CEO; President & COO; DirectorCEO Mar 2016–Feb 2019; COO May 2008–Feb 2019; Director Mar 2016–Dec 2018; 29 years at Gilead in totalSenior leadership roles at a major biopharma; extensive operating and board experience
UCSF Medical CenterPostdoctoral Research FellowPrior to joining GileadScientific training relevant to biotech R&D

External Roles

OrganizationRoleTenure (as disclosed)Committees/Impact
Pacific Biosciences of California (PACB)DirectorSince July 2013Public company board experience
TurnCare, Inc. (private)DirectorSince Dec 2023Med‑tech governance exposure
Kailera Therapeutics (private)DirectorSince Oct 2024Clinical‑stage biopharma governance
Ohio Wesleyan UniversityChair, Board of TrusteesCurrentHigher‑ed board leadership

Board Governance

  • Board/committee structure: FDMT maintains Audit, Compensation, Nominating & Corporate Governance, and Science & Technology committees; Milligan is not listed as a member of these committees .
  • Executive Chairman responsibilities: Presides over Board meetings and executive sessions; liaison between management and the Board .
  • Independence: The Board deems all directors other than the CEO (Kirn) to be independent; this includes Milligan .
  • Attendance: In 2024, the Board met 7 times; each director attended at least 75% of Board and assigned committee meetings .
  • Board classes/tenure: Class III; current term expires at the 2026 annual meeting .

Fixed Compensation (Director)

Component2024 Amount (USD)Notes
Executive Chair annual retainer (cash)$150,000Paid in lieu of standard director cash retainers/committee fees .
  • 2024 total reported director compensation for Milligan: $646,807 (Fees Earned in Cash $150,000; Option Awards grant‑date fair value $496,807) .

Performance Compensation (Director Equity)

Grant TypeGrant TimingShares/OptionsGrant‑Date Fair Value (USD)VestingExercise Price
Stock OptionAutomatically on 2024 annual meeting date (per policy)26,791$496,80733.3% vests on first anniversary; 1/36th monthly thereafter; unvested accelerates on change in controlFMV on grant date (policy)
  • Director annual equity policy for 2024: non‑employee directors received 22,500 options; Executive Chairman received 26,791 options; unvested director options accelerate in full upon change in control (single‑trigger for director grants) .

Other Directorships & Interlocks

CompanyTypeRoleInterlocks/Notes
Pacific Biosciences of CaliforniaPublicDirectorNo FDMT compensation committee interlocks disclosed for 2024 .
TurnCare, Inc.PrivateDirector
Kailera TherapeuticsPrivateDirector
Ohio Wesleyan UniversityNon‑profit/EducationChair, Board of Trustees
  • Compensation Committee interlocks and insider participation: None of FDMT’s Compensation Committee members were FDMT employees or had interlocks in 2024 .

Expertise & Qualifications

  • Strategic/operating leadership: Former CEO/COO of Gilead with 29 years at the company, bringing deep scaling and execution experience in biopharma .
  • Governance: Longstanding public company directorship at PACB; current Executive Chairman at FDMT presiding over meetings and executive sessions .
  • Education/technical: Ph.D. in Chemistry; scientific training (UCSF), supporting oversight of R&D‑intensive programs .

Equity Ownership

MetricAmountAs of/Notes
Shares beneficially owned (total)534,1741.1% of outstanding shares .
Of which: outstanding shares held directly (trust)100,000John F. Milligan & Kathryn Bradford Milligan Trust .
Of which: options exercisable within 60 days434,174Included in beneficial ownership per SEC rules .
Options outstanding (exercisable + unexercisable)463,284As of 12/31/2024 (director total option awards outstanding) .
Hedging/Pledging disclosureHedging transactions prohibited by policy; no pledging disclosure notedInsider Trading Compliance Policy prohibits hedging; pledging not mentioned .

Governance Assessment

  • Positives

    • Independence and separation from management: Board deems Milligan independent despite Executive Chairman title; independent directors meet in executive session, and he presides as Executive Chairman .
    • Attendance and engagement: Board met 7 times in 2024; each director met the ≥75% attendance threshold, indicating baseline engagement .
    • Pay structure alignment: Majority of director compensation is equity‑based (options), aligning interests with shareholders; 2024 mix for Milligan was ~$497k option grant vs $150k cash .
  • Watch items / potential red flags

    • Single‑trigger equity acceleration for directors: Any unvested director options vest in full upon a change in control, which some investors view as less aligned than double‑trigger constructs .
    • Executive session leadership: While he is independent, having the Executive Chairman preside over executive sessions (rather than a Lead Independent Director) is atypical; however, the Board confirms all directors other than the CEO are independent .
  • No identified conflicts/related‑party exposure tied to Milligan: 2023–2024 related‑party transactions disclosed involve other insiders (e.g., CEO Kirn/Reignite; CSO Kasahara service; employment of COO’s family member) and do not implicate Milligan .

  • No compensation committee interlocks: FDMT disclosed none for 2024, reducing conflict risk in pay decisions .

Director Compensation Detail (2024)

ComponentMilligan (USD)
Cash (Executive Chair retainer)$150,000
Option Awards (grant‑date fair value)$496,807
Total$646,807

Board Committee Involvement (2024 reference)

CommitteeMembers (as disclosed)Chair
AuditChacko; Gray; TheuerChacko
CompensationGray; Miller‑Rich; TomaselloGray
Nominating & Corporate GovernanceChacko; Theuer; TomaselloTomasello
Science & TechnologyTheuer; Miller‑Rich; TomaselloTheuer

Milligan is not listed on any committee; he serves in the Executive Chairman role .

Change‑in‑Control and Clawback Context

  • Director equity: Unvested director option grants accelerate in full upon a change in control (single‑trigger for director awards) .
  • Company clawback policy: FDMT adopted a Dodd‑Frank/Nasdaq‑compliant compensation recovery policy applicable to current/former executive officers for erroneously awarded incentive pay after Oct 2, 2023; as a director, Milligan’s director equity is not within the executive‑officer clawback scope described .

Meeting/Shareholder Engagement

  • Board/Committee meetings held in 2024: Board (7), Audit (5), Compensation (8), Nominating & Corporate Governance (3), Science & Technology (2); each director ≥75% attendance .
  • Annual meeting attendance: Encouraged but not mandatory; five directors attended the 2024 annual meeting .

Summary Implications for Investors

  • Milligan brings seasoned large‑cap biopharma operating and governance experience and is deemed independent, supporting board effectiveness and oversight .
  • Equity‑heavy director pay and meaningful option holdings promote alignment, though single‑trigger acceleration is a governance watch item some investors may flag in change‑in‑control scenarios .
  • No disclosed related‑party transactions or compensation committee interlocks involving Milligan, reducing conflict risk .