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Robert J. Gould

Director at Fulcrum Therapeutics
Board

About Robert J. Gould

Robert J. Gould, Ph.D., age 70, has served on Fulcrum Therapeutics’ board since July 2016, including roles as President & CEO (2016–2021) and interim CEO (Jan–Jun 2023). He is currently an operating partner at Khosla Ventures, with prior leadership at Epizyme (CEO) and senior roles at Merck, plus scientific leadership at the Broad Institute. He holds a B.A. from Spring Arbor University, a Ph.D. from the University of Iowa, and completed postdoctoral studies at Johns Hopkins University .

Past Roles

OrganizationRoleTenureCommittees/Impact
Fulcrum TherapeuticsDirectorJul 2016–presentLong-tenured director; deep company knowledge from prior CEO service
Fulcrum TherapeuticsPresident & CEOJul 2016–Mar 2021Led company through clinical and corporate milestones
Fulcrum TherapeuticsInterim President & CEOJan–Jun 2023Transitional leadership before appointment of current CEO
Epizyme, Inc.President & CEO; DirectorMar 2010–Sep 2015; Director 2010–2016Grew a clinical-stage biopharma; board oversight
Broad Institute (MIT/Harvard)Director of Novel TherapeuticsDec 2006–Mar 2010Led translational science initiatives
MerckVice President, Licensing & External Research (after 23-year tenure)Various (culminating in VP role)Business development and external innovation leadership

External Roles

OrganizationRoleTenureCommittees/Impact
Khosla VenturesOperating PartnerSep 2021–presentEarly-stage company formation and portfolio support
Turnstone Biologics CorpDirectorCurrentPublic company board; oncology biotechnology focus
Epizyme, Inc.Director2010–2016Governance during growth and clinical progress

Board Governance

  • Committee assignments: Chair, Science & Technology Committee; member alongside Colin Hill and Alan Ezekowitz .
  • Independence status: Not independent under Nasdaq rules due to interim CEO service through June 2023 .
  • Board and committee attendance: Board met 7 times in 2024; each director attended ≥75% of board and committee meetings while serving . All then-serving directors attended the 2024 annual meeting .
  • Executive sessions: Independent directors meet in executive session at least twice a year; board chair (Kate Haviland) is independent .

Fixed Compensation

Component2024 Amount ($)Notes
Cash fees50,000 Consistent with board member retainer ($40k) plus Science & Technology Committee member ($5k) and chair increment ($5k)
Option awards (grant-date fair value)167,559 Equity compensation under 2019 Plan; time-based vesting
Total217,559 2024 director compensation summary

Director fee schedule (policy-level):

Role/CommitteeMember Annual Fee ($)Chair Incremental Annual Fee ($)
Board of Directors40,000 30,000
Audit Committee7,500 7,500
Compensation & HCM Committee5,000 5,000
Nominating & Governance Committee4,000 4,000
Science & Technology Committee5,000 5,000

Performance Compensation

Equity ProgramGrant SizeVestingNotes
Initial director grant (pre-2025 program)60,000 options 2.7778% monthly over 36 monthsTime-based; granted upon initial appointment/election
Annual director grant (pre-2025 program)30,000 options Full cliff vest at 1 year or before next AGMGranted after annual meeting if ≥6 months of service
Revised program (effective Jan 24, 2025)Initial 72,000 options; Annual 36,000 options Initial: monthly over 36 months; Annual: 1-year cliffChange enhances equity alignment; options accelerate on specified change-in-control

2024 equity metrics (Robert J. Gould):

  • Options outstanding (12/31/2024): 655,532 shares .
  • 2024 option grant fair value recognized: $167,559 .
  • Program mechanics: All director options issued at fair market value on grant date and accelerate upon specified change-in-control .

Other Directorships & Interlocks

CompanyRolePublic/PrivateInterlocks/Conflicts Noted
Turnstone Biologics CorpDirectorPublic biopharmaNo interlocks disclosed with Fulcrum’s comp committee; none reported
Epizyme, Inc.Former DirectorPublic biopharmaHistorical role; no current interlocks

Compensation committee interlocks: None reported among current or 2024 committee members; no Fulcrum executives served on other companies’ boards/comp committees creating interlocks .

Expertise & Qualifications

  • Deep biopharma leadership (CEO Epizyme; VP Merck; Broad Institute translational science) .
  • Long-tenured Fulcrum insider with prior CEO and interim CEO service, offering domain and company-specific expertise .
  • Scientific governance leadership as Science & Technology Committee chair overseeing R&D strategy and pipeline reviews .

Equity Ownership

MetricValueAs-of Date
Total beneficial ownership (shares)1,125,396 Mar 31, 2025
Ownership (% of outstanding)2.1% Mar 31, 2025
Breakdown: common shares499,864 Mar 31, 2025
Breakdown: options (exercisable ≤60 days)625,532 Mar 31, 2025
Options outstanding (policy disclosure)655,532 Dec 31, 2024

Policy alignment:

  • Anti-hedging and anti-pledging policy prohibits hedging and pledging, with rare exceptions requiring demonstrable repayment capacity; applies to directors .
  • Compensation recovery (clawback) policy effective Nov 2023; administered by the Compensation & HCM Committee; applies per Nasdaq Rule 10D-1 framework .

Governance Assessment

  • Board effectiveness and engagement: As Science & Technology Committee chair, Gould provides strong R&D oversight and strategic input; board attendance thresholds were met in 2024 (≥75%) and directors attended the 2024 annual meeting, supporting engagement .
  • Independence and potential conflicts: Gould is not independent under Nasdaq rules due to interim CEO service in 2023—this can be perceived as a governance risk for roles requiring independence; he is appropriately not seated on audit or compensation committees, mitigating independence-sensitive conflicts .
  • Ownership alignment: Material beneficial ownership (2.1%) enhances “skin-in-the-game”; no pledging or hedging disclosed, consistent with policy .
  • Director compensation mix: Balanced cash retainer plus at-risk equity via options; vesting is time-based (no performance metrics), and options only have value with share price appreciation, aligning incentives with shareholder outcomes .
  • Compensation process and safeguards: Use of independent consultant (Aon) with no conflicts identified; policies include anti-hedging/pledging and clawback, reinforcing investor protections .

RED FLAGS

  • Non-independence classification due to recent interim CEO role (per Nasdaq rules) .
  • Time-based equity for directors lacks explicit performance metrics; while common for boards, it reduces direct pay-for-performance linkage versus performance-based units .

Potential related-party/transactions

  • No related person transactions involving Gould disclosed in 2023–2025; RA Capital and other holder transactions noted but unrelated to Gould .