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Donald Nicholson

Director at Generation Bio
Board

About Donald Nicholson

Donald Nicholson, Ph.D., is an independent director of Generation Bio (GBIO) who has served on the board since December 2017. He earned a B.S. with honors and a Ph.D. in biochemistry from the University of Western Ontario and completed a Medical Research Council postdoctoral fellowship at the University of Munich; he previously spent 25 years at Merck in leadership roles and served as executive officer of Nimbus Therapeutics from August 2014 to October 2018 . The board determined in April 2025 that all directors other than the CEO are independent under Nasdaq rules, which includes Dr. Nicholson; board and committee attendance for all directors met or exceeded the 75% threshold in 2024 . Age: 67 .

Past Roles

OrganizationRoleTenureCommittees/Impact
Nimbus TherapeuticsExecutive officerAug 2014 – Oct 2018Executive leadership in biotech strategy and operations
Merck & Co., Inc.Various leadership, strategic and operational roles~25 yearsLarge-cap pharma experience and operating discipline

External Roles

OrganizationPublic/PrivateRoleTenureCommittees/Impact
Disc Medicine, Inc. (f/k/a Gemini Therapeutics)PublicDirectorSince Apr 2019Not disclosed
Kymera Therapeutics, Inc.PublicDirector (former)Nov 2017 – Nov 2022Not disclosed
Jnana Therapeutics Inc.PrivateDirectorSince Feb 2019Not disclosed
NodThera Inc.PrivateDirectorSince Apr 2019Not disclosed
Muna TherapeuticsPrivateDirectorSince Sep 2021Not disclosed
Matchpoint Therapeutics, Inc.PrivateDirectorSince Nov 2022Not disclosed

Board Governance

  • Committee assignments (2024): Talent Committee (member); not on Audit or Nominating & Governance. Talent Committee met 4 times in 2024; Audit 5; Nominating & Governance 2 . Independence: Board determined all non-employee directors (including Nicholson) are independent under Nasdaq rules (April 2025) .
  • Attendance: In 2024, each director, including committee service, attended at least 75% of aggregate meetings; full board met 5 times .
  • Talent Committee interlocks: During 2024, Talent Committee members (including Nicholson) were not officers/employees of GBIO; no compensation committee interlocks disclosed; no member (or immediate family) had a direct/indirect material interest in a company transaction >$120,000, except as otherwise disclosed under “Transactions with Related Persons” .
  • Oversight scope: Audit Committee reviews related person transactions, among other responsibilities .

Fixed Compensation

2024 Non‑Employee Director CompensationFees Paid in Cash ($)Option Awards ($)Total ($)
Donald Nicholson, Ph.D.47,500 166,476 213,976
Director & Committee Fee Schedule (effective 2024)Member Annual Fee ($)Chair Annual Fee ($)
Board of Directors40,000 30,000
Audit Committee7,500 7,500
Talent Committee7,500 7,500
Nominating & Corporate Governance4,000 4,000

Mix signal: In 2024, Nicholson’s equity award value materially exceeded cash retainer (166,476 vs. 47,500), indicating an equity-heavy pay mix that aligns director incentives with shareholder value .

Performance Compensation

Director Equity Program Terms (amended March 2024; effective April 1, 2024)Detail
Initial equity grantStock option for 60,000 shares at first election; vests 1/36 monthly over 3 years; 10‑year term; strike = FMV on grant date
Annual equity grantStock option for 30,000 shares on each annual meeting date (if ≥6 months of service); 100% vests on earlier of 1‑year anniversary or next annual meeting; 10‑year term; strike = FMV
Nicholson Equity Position (as of 12/31/2024)Amount (shares)
Options outstanding (aggregate)171,200

Committee context: The Talent Committee (serves as Compensation Committee) is independent and engages independent compensation advisors; it affirmed CD&A inclusion and governance controls in 2024 .

Other Directorships & Interlocks

CategoryDetail
Public company boardsDisc Medicine (current), Kymera Therapeutics (former)
Compensation interlocksNone disclosed for GBIO’s Talent Committee in 2024; no material related-person interests >$120,000 for members, except as otherwise disclosed
Related-party transaction policyTransactions reviewed/approved per policy; Audit Committee oversees related person transactions

Expertise & Qualifications

  • Scientific and operating depth: 25 years at Merck in leadership roles; executive officer at Nimbus Therapeutics .
  • Academic credentials: B.S. (honors) and Ph.D. in biochemistry (University of Western Ontario); MRC postdoctoral fellow (University of Munich) .
  • Board skills: Experience across multiple clinical-stage biopharma boards (public and private) supports Talent Committee service and compensation oversight .

Equity Ownership

Beneficial Ownership (Record Date; 67,013,359 shares outstanding)Shares% Outstanding
Donald Nicholson, Ph.D. – Total384,776 <1%
— Held directly213,576 n/a
— Options exercisable within 60 days171,200 n/a
  • Anti‑hedging/pledging policy: Insider Trading Policy prohibits hedging (short sales, options, swaps, collars) and generally prohibits purchasing on margin, borrowing against, or pledging GBIO securities; preclearance required for certain transactions .
  • Ownership guidelines: Not disclosed for directors in the 2025 proxy (no guideline details provided) .

Governance Assessment

  • Positives:
    • Independent director with strong life sciences operating and scientific background; current service on Talent Committee (compensation oversight) .
    • Attendance at or above required levels; board and committee engagement evident (≥75% in 2024) .
    • Equity-heavy director pay structure and option-only annual grants align director economics with shareholder outcomes; strike set at FMV; 10‑year term; time-based vesting .
    • No compensation committee interlocks; no material related-person transactions for Talent Committee members (including Nicholson) in 2024; related-party transactions overseen by Audit Committee .
    • Anti‑hedging and anti‑pledging policy strengthens alignment and mitigates governance risk .
  • Monitoring items:
    • Multiple external directorships (public and private) are common in biotech but warrant continued monitoring for time commitments and potential conflicts; no conflicts disclosed in the proxy .
    • Director ownership guidelines not disclosed; equity alignment is instead driven by option program design .

Summary signal: Nicholson’s independence, committee role in compensation oversight, attendance, and equity-aligned pay structure support investor confidence, with no red flags disclosed on interlocks, related-party transactions, hedging/pledging, or attendance .