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Darya Chudova

Chief Technology Officer at Guardant HealthGuardant Health
Executive

About Darya Chudova

Chief Technology Officer (CTO) at Guardant Health since May 8, 2023; at Guardant since August 2015. Age 51; Ph.D. in Computer Science from UC Irvine. Led development of Guardant’s Shield blood-based colorectal cancer screening technology to FDA approval and commercial launch in July–August 2024, earning a one-time $25,000 bonus for this milestone . Company performance under her tenure as CTO: revenue grew 25% in 2023 and 31% in 2024; non-GAAP adjusted EBITDA loss improved from $344.2M (2023) to $257.5M (2024); say-on-pay support rose to 93.6% in 2024, signaling investor endorsement of pay design tied to growth and product launches .

Past Roles

OrganizationRoleYearsStrategic Impact
Guardant HealthSVP, Technology2015–2023Led technical development of Guardant360 LDT/CDx and Shield; improved precision, robustness, accessibility of liquid biopsy tests
IlluminaTechnology lead (NIPT)2013–2015Developed non‑invasive prenatal testing (NIPT) capabilities
VeracyteGenomic tools developer2008–2013Built tools for clinical diagnostics and interpretation of genomic data in molecular cytology

External Roles

Not disclosed for Dr. Chudova in company filings .

Fixed Compensation

Metric20232024
Base Salary ($)424,462 487,308
Target Bonus (%)50% (blended from 40% pre‑promotion) 50%
Actual Annual Incentive (Cash/PSU) ($)279,281 375,000
Bonus (One‑time spot/achievement) ($)35,000 (25k spot + 10k achievement)
Stock Awards ($)2,222,397 1,479,151
Option Awards ($)1,817,482 1,078,577
All Other Compensation ($)11,919 20,487
Total ($)4,755,541 3,475,523

Performance Compensation

ComponentWeightTargetActualPayout/Achievement
Revenue excluding screening ($M)30%670 733.9 200%; weighted 60%
Non‑GAAP Gross Margin % excl screening5%60% 64% 200%; weighted 10%
Adjusted EBITDA ($M)10%(306) (257.5) 200%; weighted 20%
Oncology Product Milestones (launches, data)25%Set by committee Mixed above‑target/below‑threshold Weighted 32.5%
Screening R&D (Shield launch, device validation)25%Set by committee Target/below‑target Weighted 22.5%
Employee Engagement5%Target TargetWeighted 5%
Total Achievement150% company‑wide payout factor

2024 PSU grants for NEOs (performance equity): Darya target $600,000; 17,063 PSUs. One‑year revenue growth component earned at 200% on 31% revenue growth; vests 1/3 on Mar 1, 2025, remainder on Jan 1, 2026 and Jan 1, 2027. Three‑year revenue CAGR component subject to a relative TSR modifier with a negative TSR cap; targets disclosed post‑period .

Equity Ownership & Alignment

  • Beneficial Ownership: 108,394 shares (<1% of outstanding; 121,885,230 shares outstanding on Apr 15, 2024). Approximate ownership = 0.089% .
  • Stock Ownership/Trading Policies: Executive stock ownership and retention guidelines; strict prohibition on hedging, pledging, margin, and short sales of company securities .
InstrumentGrant DateStatus (FY‑end 2024)UnitsTerms
RSUs11/8/2024Unvested39,689; $1,212,499 MV Annual RSUs vest 1/3 after 1 year, then quarterly over 3 years (2024 cycles)
RSUs12/13/2023Unvested13,338; $407,476 MV 2023 RSUs vest over 4 years
RSUs8/7/2023Unvested26,116; $797,844 MV 4‑year vest
RSUs11/7/2022Unvested10,714; $327,313 MV 4‑year vest
PSUs (2024 one‑year revenue)2/26/2024Earned/UnvestedEarned: 17,062; $521,244 MV; Unvested tranche: 8,532; $260,653 MV Vest 1/3 Mar 1, 2025; 1/3 Jan 1, 2026; 1/3 Jan 1, 2027
PSUs (2023 program)6/7/2023Unvested10,714; $327,313; Unvested 5,357; $163,656 Three‑year CAGR + 2023 one‑year revenue component; service‑based vesting
PSUs (2020 program)11/4/2020Earned21,863; $667,915 MV Earned upon hitting $600M run‑rate revenue and Shield Medicare‑reimbursable order; vested in Q1 2025 (6 months after second milestone)
Options11/8/2024Unexercisable59,534 @ $28.61; exp 11/8/2034 10‑year; options vest over 3 years (1/3 year 1; monthly thereafter)
Options12/13/2023Exercisable/Unexercisable11,521 / 18,340 @ $28.37; exp 12/13/2033 Same vest schedule
Options8/7/2023Exercisable/Unexercisable20,675 / 31,557 @ $37.50; exp 8/7/2033 Same vest schedule
Options11/7/2022Exercisable/Unexercisable23,212 / 19,642 @ $47.20; exp 11/7/2032 Standard vesting
Options11/2/2021Exercisable/Unexercisable8,206 / 1,894 @ $117.61; exp 11/2/2031 Standard vesting
Options8/1/2019Exercisable17,442 @ $94.47; exp 8/1/2029 Standard vesting
Options8/22/2018Exercisable2,356 @ $8.80; exp 8/22/2028 Standard vesting
Options3/30/2018Exercisable4,328 @ $4.6625; exp 3/30/2028 Standard vesting

Vesting cadence implies regular RSU/PSU delivery events (Mar and Jan tranches; plus quarterly RSUs), which can create periodic liquidity windows; anti‑hedging/pledging policies mitigate misalignment risks .

Employment Terms

ProvisionNon‑CIC TerminationCIC Termination (Double Trigger)
Tier classificationTier 2 (CTO) Tier 2
Cash severance12 months base salary (lump sum) 18 months base salary (lump sum)
BonusPro‑rated target bonus for year of termination Target bonus for year of termination
Health benefits (COBRA)Company‑paid up to 12 months Company‑paid up to 18 months
Equity accelerationTime‑based RSUs/options vest fully upon CIC termination; PSUs vest at greater of target or actual as of CIC Same
ClawbackCompany clawback policy adopted Nov 2023; Compensation Committee administers
Anti‑hedging/pledgingProhibited for employees and directors

Performance & Track Record

  • Shield FDA approval and national launch in July–August 2024; Medicare pricing secured in November 2024; credited with spot/achievement bonuses for foundational contributions .
  • Led Smart Platform and Infinity AI integration to drive multimodal (genomic + epigenomic) insights, scaling automation and cost efficiency; expanded phenotypic biomarker readouts via Guardant360 and supported therapy selection upgrades .

Company Performance (context for pay‑for‑performance)

MetricFY 2022FY 2023FY 2024
Revenues ($)449,538,000 ]563,948,000 ]739,016,000 ]
EBITDA ($)-508,416,000*-438,444,000*-401,207,000*

*Values retrieved from S&P Global.

Risk Indicators & Red Flags

  • Late Section 16 filings: Two late Form 4s for June 1, 2023 and August 1, 2023 RSU vesting/tax withholding due to administrative error (company disclosed) .
  • Governance protections: Clawback policy (Nov 2023); robust anti‑hedging/pledging; double‑trigger CIC vesting; no excise tax gross‑ups; annual compensation risk assessment .

Compensation Peer Group (benchmarking alignment)

  • 2024/2025 peer sets include: 10x Genomics, Natera, NeoGenomics, EXACT Sciences, Blueprint Medicines, Exelixis, Penumbra, Repligen, Veracyte, Myriad Genetics, iRhythm, Novocure, Glaukos, Lantheus, Twist Bioscience, Ultragenyx, ACADIA; updated for size/revenue comparability and market evolution .

Say‑on‑Pay & Shareholder Feedback

  • Say‑on‑Pay approval: ~86.5% (2023) and 93.6% (2024). Board engaged top holders to refine incentives; shift to balanced cash/equity and PSU emphasis tied to revenue growth and TSR .

Investment Implications

  • Alignment: CTO compensation is meaningfully at‑risk, with large PSU components tied to one‑year revenue growth (earned at 200% in 2024) and three‑year revenue CAGR with a TSR modifier—linking payouts to growth and shareholder returns .
  • Supply overhang timing: Earned PSUs vest across Mar 2025/Jan 2026/Jan 2027; RSUs vest quarterly (recent annual RSUs begin cliff vesting one year post‑grant), implying recurring insider liquidity windows, albeit constrained by anti‑hedging/pledging and retention guidelines .
  • Retention and CIC economics: Tier 2 severance (18 months base + target bonus + full equity vesting on double trigger) is competitive, reducing retention risk while potentially increasing CIC‑related dilution if performance awards are deemed at target upon termination .
  • Execution signal: The 2024 payout factor (150%) was driven by 31% revenue growth, margin improvement, and product milestones, with the CTO’s Smart Platform/Shield advances likely underpinning sustained growth trajectory .