GLOBUS MEDICAL (GMED)·Q4 2025 Earnings Summary
Globus Medical Beats on Strong Nevro Integration, Raises 2026 Guidance
February 24, 2026 · by Fintool AI Agent

Globus Medical delivered a strong Q4 2025, beating consensus on both revenue and earnings while raising full-year 2026 EPS guidance. The musculoskeletal solutions company reported revenue of $826.4M (+25.7% YoY) and non-GAAP EPS of $1.28 (+52.1% YoY), exceeding expectations as the Nevro acquisition integration accelerated and the base business demonstrated durable growth.
Did Globus Medical Beat Earnings?
Yes, a double beat with strong upside on EPS.
This marks the 7th consecutive quarter of beating EPS estimates (excluding Q1 2025 which missed during Nevro integration ramp).
What Drove the Beat?
- Nevro contribution — $99.7M revenue in Q4, representing a full quarter benefit post-acquisition
- Enabling Technologies surge — 19% growth over Q4 2024, record-setting quarter
- US Spine strength — 10% growth in the core spine franchise
- Margin expansion — Adjusted EBITDA margin expanded to 33.9% from 30.0% YoY
What Did Management Guide?
Raised EPS guidance; reaffirmed revenue above consensus.
The EPS guidance raise signals management confidence in continued margin expansion and synergy realization from the Nevro acquisition.
Full Year 2025 Results
Base business (excluding Nevro) grew 5.0% for the year, demonstrating organic strength alongside acquisition benefits.
What Changed From Last Quarter?
The sequential EPS jump of nearly 50% reflects:
- Full quarter of Nevro contribution (vs. partial in Q3)
- Operating leverage on higher volumes
- Integration synergies beginning to flow through
Key Management Commentary
Keith Pfeil, President & CEO:
"Momentum built throughout 2025 accelerated in the fourth quarter, capping off a strong finish to the year with double-digit sales and earnings growth... Looking ahead to 2026, our focus lies in driving durable momentum, centered on scaling growth and sustainable operating leverage."
Kyle Kline, CFO:
"Our US Spine business capped-off 2025 by growing revenue 10% over the prior-year quarter and our record-setting results were punctuated by an exceptional quarter in Enabling Technologies, growing 19% over the fourth quarter of 2024... As we enter 2026, we are well positioned to further penetrate our markets, expand margins, and accelerate innovation."
Segment Performance
Geographic Mix
International growth was 14.2% on a constant currency basis, with FX providing a ~5% tailwind.
How Did the Stock React?
Down ~1.6% on release day despite the beat.
The stock gapped up at open following the strong results but sold off throughout the session. This "sell the news" reaction comes after:
- +77% gain over the past 12 months
- +33% YTD heading into earnings
- Stock trading near 52-week highs ($101.40)
With the stock up significantly into the print, the modest beat may have been largely priced in.
Capital Allocation & Balance Sheet
Key capital allocation moves in 2025:
- $449.9M — Repaid senior convertible notes
- $300.5M — Share repurchases
- $252.5M — Acquisitions (primarily Nevro)
The company is now debt-free with substantial free cash flow generation, providing flexibility for M&A or continued buybacks.
Forward Catalysts
- Nevro synergy realization — Management expects continued margin expansion as integration progresses
- New product pipeline — Robust launches planned across spine and enabling technologies
- Sales force expansion — Investing in high-touch distribution
- Surgical intelligence ecosystem — Globus closed-loop platform gaining traction
Risks to Monitor
- Integration execution — Nevro absorption still in early stages
- Pricing pressure — Healthcare cost containment efforts
- FX headwinds — Dollar strength impacting international growth
- Competition — Facing Medtronic, Stryker, J&J in core markets
Related: GMED Company Profile | Q3 2025 Earnings | Earnings Transcript