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Bryan Giraudo

Chief Operating Officer and Chief Financial Officer at Gossamer BioGossamer Bio
Executive

About Bryan Giraudo

Chief Operating Officer (since September 2021) and Chief Financial Officer (since May 2018) of Gossamer Bio. Age 50; B.A. from Georgetown University . 2024 business execution included advancing the Phase 3 PROSERA study and signing a global collaboration with Chiesi for seralutinib . Pay-versus-performance disclosures show challenging shareholder returns and losses over 2022–2024: TSR value of a $100 initial investment was $22 (2022), $9 (2023), $8 (2024), while net losses were $(229.4)M (2022), $(179.8)M (2023), $(56.5)M (2024) .

Metric202220232024
TSR – Value of $100 Investment ($)22 9 8
Net Income (Loss) ($)(229,378,000) (179,817,000) (56,528,000)

Past Roles

OrganizationRoleYearsStrategic Impact
Leerink PartnersSenior Managing Director2009–Apr 2018 Led western North America and APAC biotech/medtech banking
Merrill Lynch (Global Healthcare IB)Managing DirectorNot disclosed Senior investment banking leadership in healthcare

External Roles

OrganizationRoleYears
Protagonist Therapeutics, Inc.DirectorSince May 2018
Onxeo S.A.DirectorSince Nov 2021

Fixed Compensation

Metric20232024
Base Salary ($)485,624 502,645
Target Bonus (% of Base)45% (unchanged from 2023) 45%
Actual Bonus Paid ($)218,467 232,977
Option Awards (Grant-Date Fair Value, $)579,791 (includes $283,292 incremental fair value from May 2023 repricing) 432,281

Performance Compensation

2024 annual incentive plan mechanics (corporate and individual factors):

ComponentWeightingTargetActualPayout Impact
Corporate performance70% 100%95% Drives 70% of payout based on company score
Individual performance (Giraudo)30% 100%120% Drives 30% of payout based on individual factor
Target bonus %45% of base salary
Actual bonus paid ($)232,977 Reflected in SCT

2024 corporate goals and measured results:

2024 Corporate GoalWeightAchievementWeighted Performance
PROSERA patient enrollment40% 87.5% 35%
PDCO agreement on Pediatric Plan10% 100% 10%
FDA feedback on PH-ILD Phase 3 and EMA feedback timing10% 100% 10%
Commercial readiness gap assessment5% 100% 5%
Joint U.S. commercial plan under partnership10% 100% 10%
Global partnership execution20% 100% 20%
Global development plan under partnership5% 100% 5%
Total corporate performance95%

Equity instruments and vesting:

  • Annual options vest 25% after 1 year, then monthly over the next 36 months; certain grants vest over three years; 2023 included a CEO performance option with price hurdles, not applicable to Mr. Giraudo .

Equity Ownership & Alignment

MetricAmount
Total beneficial ownership (shares)2,181,602
Ownership (% of outstanding)1.0%
Direct/common shares (incl. family trust)572,747
Options exercisable within 60 days1,595,350
Warrants exercisable within 60 days13,505
  • Insider trading policy prohibits pledging, hedging, margin purchases, short sales, and derivatives on company stock .
  • Stock ownership guidelines were not disclosed; compliance status not stated .

Outstanding Equity Awards (as of 12/31/2024)

Grant DateExercisable (#)Unexercisable (#)Exercise Price ($)Expiration
1/2/2024543,750 0.97 1/2/2034
11/20/202349,088 132,162 0.84 11/20/2033
3/20/202392,531 118,969 1.21 3/20/2033
12/7/2022140,647 70,853 2.16 12/7/2032
1/6/2022171,742 4,933 1.36 1/6/2032
9/16/202181,251 18,753 1.36 9/16/2031
2/25/202157,500 2,502 1.36 2/25/2031
2/14/202047,668 1.36 2/14/2030
3/25/201996,671 1.36 3/25/2029
12/10/2018155,555 10.71 12/10/2028
5/21/2018405,666 2.61 5/21/2028

Notes:

  • Certain options were repriced on May 5, 2023, reflected in exercise prices and incremental fair value accounting in 2023 .

Employment Terms

ScenarioCash SeveranceBonusHealth (COBRA)Equity AccelerationTrigger Type
Termination without cause/for good reason (pre‑CIC or >12 months post‑CIC)9 months base salary Not specified Up to 9 months paid premiums Death/disability: greater of 50% of unvested awards or awards vesting over next 9 months Single termination (no CIC)
Termination without cause/for good reason within 12 months after CIC12 months base salary Target annual bonus paid Up to 12 months paid premiums Full vesting/exercisability of unvested awards Double trigger (CIC + termination)
ClawbackApplies per SEC/Nasdaq rules; recovery of erroneously paid incentive comp
Tax gross‑upsNone; no post‑employment tax gross‑ups
280G cutback“Better‑off” cutback applies
Hedging/pledgingProhibited per policy

Historical promotion terms:

  • Upon promotion to COO/CFO (Sept 2021): base salary $460,000; target bonus 45%; severance included salary continuation, pro‑rated target bonus (non‑CIC), and extended benefits; enhanced severance and bonus without proration in CIC; plus a 150,000‑share option grant on 9/16/2021 .

Compensation Structure Analysis

  • Cash vs equity: Target total cash around 50th percentile of peers; annual equity awards around the 62nd percentile per Alpine Rewards benchmarking; peer group updated in 2024 to reflect market cap, stage, and headcount .
  • Options repricing: Company permits option/SAR repricing without shareholder approval under the plan; Mr. Giraudo’s options were repriced in May 2023 (incremental fair value $283,292) . Repricing is a governance red flag and can increase perceived insider value protection .
  • Pay-for-performance: 2024 corporate performance set at 95% with individual factor 120%, yielding an SCT-reported bonus of $232,977 for Mr. Giraudo .
  • Equity dilution and overhang: The Restated Plan increases the share reserve and extends the evergreen through 2035; overhang and burn rates are monitored, but added authorization increases potential dilution .

Risk Indicators & Red Flags

  • Option repricing allowed and used (2023) .
  • Full single-trigger prohibition: Plan indicates no single-trigger vesting on CIC (awards accelerate if not assumed, otherwise double-trigger applies) .
  • Hedging/pledging ban reduces alignment risk; no pledging disclosed for Mr. Giraudo .
  • Indemnification agreements in place for directors and executive officers .

Equity Ownership & Alignment Details

  • Beneficial ownership: 2,181,602 shares (1.0% of outstanding). Composition: 572,747 common shares (incl. family trust), 1,595,350 options exercisable within 60 days, and 13,505 warrants exercisable within 60 days .
  • Ownership guidelines: Not disclosed; policy prohibits hedging/pledging .

Expertise & Qualifications

  • Investment banking background (Leerink, Merrill Lynch) with regional and sector leadership; director experience at Protagonist Therapeutics and Onxeo S.A.; formal finance and operations credentials through COO/CFO roles .

Investment Implications

  • Retention risk appears moderate: double-trigger severance with full acceleration post-CIC and meaningful unvested equity provide retention and CIC incentives; pre‑CIC severance excludes target bonus under current letter, lowering windfall risk .
  • Potential selling pressure from option vesting: substantial blocks from recent grants (e.g., 543,750 options granted 1/2/2024 begin vesting on first anniversary and monthly thereafter), and multiple prior grants are already exercisable .
  • Governance signal: option repricing in 2023 and plan-level repricing authority are noteworthy and may be viewed negatively by some investors .
  • Alignment: 1.0% beneficial ownership, hedging/pledging bans, and performance-linked cash incentives support alignment; however, ongoing dilution risk from expanded plan reserves and evergreen extension should be monitored .