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Ruoyu Chen

Chief Financial Officer at GYRE THERAPEUTICS
Executive

About Ruoyu Chen

Ruoyu Chen, age 55, is Chief Financial Officer of Gyre Therapeutics (appointed October 2023) and a director of Gyre Pharmaceuticals (since 2018). She brings 20+ years across global finance, audit, internal control, tax, and M&A, with prior roles at GNI USA/GNI Group, Protiviti, BDO, Arthur Andersen, and MUFG Consulting; she holds a BA from Nankai University, an MA in Economics from Kyoto University, is a Washington State CPA, and a CFA Level II candidate . During her tenure as CFO, Gyre reported 2024 revenues of $105.8M and net income of $17.9M, and guided 2025 revenues to $118–$128M; the company’s cumulative TSR metric per Item 402(v) shows $134 on a $100 base for 2024 (methodology per proxy) . Ms. Chen signed multiple SEC current reports in her capacity as CFO, reflecting her role overseeing reporting and controls .

Past Roles

OrganizationRoleYearsStrategic impact
Gyre TherapeuticsChief Financial OfficerOct 2023–presentExecutive officer responsible for finance and SEC reporting .
Gyre Pharmaceuticals (subsidiary)Director2018–presentBoard oversight at operating subsidiary in PRC .
GNI USA (GNI Group)SVP Finance2021–Oct 2023Managed GNI Japan’s U.S. business operations .
GNI Group (Japan)Director of Finance & Accounting2014–2021Led investments, financing, financial reporting, public company disclosure; budget and financial analysis .
Protiviti JapanManager, Internal Audit2012–2014Internal audit management .
BDO International JapanAuditor2007–2011External audit .
Arthur Andersen JapanConsultant1999–2003Strategic consulting including ERP implementations for Japanese multinationals .
MUFG Consulting & Research JapanCorporate Strategy Consultant1997–1999Strategy consulting .

External Roles

OrganizationRoleYearsStrategic impact
Gyre Pharmaceuticals (PRC)Director2018–presentBoard role at majority indirectly owned operating company .

Fixed Compensation

YearBase Salary ($)Target Bonus (% base)Actual Cash Bonus ($)Other Compensation ($)
2024250,000 10% 25,000 10,000 (401k company contribution)
202320,833

Notes:

  • As of 12/31/2024, Ms. Chen’s base salary rate was $250,000 .
  • For 2024, NEOs were eligible for annual bonuses based on business and personal goals established by the Compensation Committee; Ms. Chen’s target was 10% of base, and her approved bonus was $25,000 .

Performance Compensation

Annual Incentive Plan (Cash)

MetricWeightingTargetActual/PayoutVesting/Timing
Company and individual goals (Compensation Committee-set) Not disclosed 10% of base salary (implied $25,000 on $250,000 base) $25,000 approved Cash bonus (timing not disclosed)

Equity Awards (Options)

Grant DateTypeSharesExercisableUnexercisableExercise Price ($)ExpirationVesting Schedule
8/14/2024Stock option50,000050,0009.988/14/203425% on 1st anniversary, then monthly over next 3 years
10/31/2023Stock option34,38034,38006.9310/31/2033Vests in equal installments on each of first 3 anniversaries
10/30/2023Stock option (replacement)578,540578,54000.7510/29/2030Fully vested replacement award post-business combination

Equity compensation accounting values:

  • 2024 “Option Awards” grant-date fair value (ASC 718): $365,516 .
  • 2023 “Option Awards” grant-date fair value (ASC 718): $187,329 .

Equity Ownership & Alignment

CategoryDetail
Total beneficial ownership972,527 shares; 1.0% of outstanding .
Composition detail (per footnote)Includes 612,920 options held by Ms. Chen exercisable within 60 days and 359,607 options held by spouse (director Thomas Eastling) exercisable within 60 days; Ms. Chen and Mr. Eastling are married .
Vested vs. unvested (as of 12/31/2024)Vested/exercisable options: 612,920; Unexercisable options: 50,000 .
Upcoming vesting cadence8/14/2024 grant: 25% vests on 8/14/2025, then monthly over 36 months; 10/31/2023 grant: equal tranches on 10/31/2024, 10/31/2025, 10/31/2026 .
Insider trading policyProhibits short-term trading, short sales, and transactions in publicly traded options/derivatives; prohibits hedging .

Implication: A large pool of already vested, low-strike options (612,920 at $0.75 and $6.93) and a separate unvested grant (50,000) could create episodic selling capacity when trading windows open, subject to policy and personal decisions .

Employment Terms

TermMs. Chen – Key terms
Employment agreement date/roleEntered upon appointment as Interim CFO on 10/30/2023; CFO since October 2023 .
Base salary$250,000 initial base .
Annual bonus eligibilityPerformance bonus based on targets/milestones set by Board/Compensation Committee .
Restrictive covenantsNon-solicitation (employees/consultants) for 12 months post-termination; perpetual non-disparagement; perpetual confidentiality .
Severance (termination without Cause or for Good Reason)12 months’ salary continuation; up to 12 months partially subsidized COBRA; accelerated vesting of equity awards scheduled to vest in the 12 months post-termination (subject to release) .
Definitions“Cause” and “Good Reason” defined (including material reduction in duties/comp, certain misconduct, and cure periods) .
Change-of-control economicsNot specifically disclosed; general severance above applies to qualifying terminations (no separate CoC multiple disclosed) .
ClawbackCompany will recover incentive-based compensation after Oct 30, 2023 if a restatement is required, consistent with Nasdaq Rule 5608/Rule 10D-1 .

Performance & Track Record (Company context during CFO tenure)

Metric20232024
Revenue ($M)113.5 105.8
Net income ($M)(85.5) 17.9
Company TSR (per Item 402(v) methodology; $100 base)398 134

2025 outlook: Company guides total revenue to $118–$128M, driven by ETUARY plus planned launches of nintedanib and avatrombopag in the PRC .

Compensation Committee & Governance Context

  • Compensation Committee: Renate Parry (Chair), David M. Epstein, Gordon Carmichael; all determined independent under Nasdaq/Exchange Act rules .
  • Consultant: Aon/Radford engaged in 2024 for executive and director compensation advice .
  • Controlled company: GNI Group-affiliated entities control ~77.9% voting power; the Company relies on controlled-company exemptions for certain governance requirements .
  • Family relationship disclosure: Ms. Chen (CFO) and director Thomas Eastling are spouses .

Investment Implications

  • Pay-for-performance alignment: 2024 cash comp was modest (base $250k, bonus $25k) while equity is the primary at-risk component (2024 option grant fair value $365.5k), aligning incentives with equity value creation and guided revenue growth initiatives .
  • Retention vs. liquidity: Unvested 50,000 options vest through 2028, offering retention hooks; however, 612,920 vested low-strike options afford liquidity flexibility that could translate into selling capacity during open windows, subject to policy and personal decisions .
  • Severance and risk posture: Severance provides 12 months’ salary, 12 months COBRA subsidy, and 12 months’ forward vesting upon a qualifying termination—moderate protection without disclosed CoC multiples, limiting “golden parachute” risk while ensuring continuity .
  • Governance considerations: Controlled company status and a spousal relationship between the CFO and a board member warrant continued monitoring of independent oversight; the Company notes all Section 16 reports were timely filed for 2024 and has adopted a compliant clawback policy and strict hedging/derivatives prohibitions .