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Thomas Eastling

Director at GYRE THERAPEUTICS
Board

About Thomas Eastling

Independent director? No—Eastling is classified as not independent because he is married to Gyre’s CFO, Ruoyu Chen . Age 65 (as of April 21, 2025); director since October 2023 (served as a director of Catalyst from December 2022 until the business combination) . Core credentials: CFO and director at Cullgen Inc. since February 2018, prior CFO and representative executive officer at GNI Group Ltd. (GNI Japan) from 2013–2021; extensive executive management, global finance, and M&A experience across New York, London, Tokyo, Hong Kong; NACD.DC Certified Director; BA (USC) and master’s from the American Graduate School of International Management .

Past Roles

OrganizationRoleTenureCommittees/Impact
Gyre Therapeutics (Catalyst Biosciences pre-merger)DirectorOct 2023–present; Catalyst director Dec 2022–Oct 2023Class III director; governance involvement
Nikko Securities Co. International, Inc.Senior Vice President & General Manager, Investment Banking and SyndicateJun 1983–Nov 1999Led IB and syndicate divisions; Wall Street start
Duff & Phelps Credit Rating Co. (now Fitch Ratings)Company Representative in JapanMay 2000–Jun 2001Credit rating market presence in Japan
SoftBank Corp.Managing DirectorJul 2001–Jul 2003Corporate leadership role
American Appraisal (Asia)Director, Transaction Advisory Services2009–Aug 2013Led Asia transaction advisory; relocated to Hong Kong
GNI Group Ltd. (GNI Japan)CFO and Representative Executive Officer2013–2021Finance leadership at vertically integrated biopharma

External Roles

OrganizationRoleTenureNotes
Cullgen Inc.CFO and DirectorFeb 2018–presentBiopharma company; ongoing board and finance leadership
GNI Group Ltd. (GNI Japan)Outside Member; Advisor to Executive CommitteeSince Apr 2013; Advisor since Sep 2013Interlock with Gyre’s controlling shareholder group

Board Governance

  • Committee assignments: Chair, Nominating and Corporate Governance Committee; not on Audit or Compensation Committees .
  • Committee meetings: 2024 meetings—Audit 4, Compensation 4, Nominating 1 .
  • Independence: Not independent due to spousal relationship with Gyre’s CFO, Ruoyu Chen .
  • Board attendance: Board met four times in 2024; each director attended at least 75% of Board and applicable committee meetings; all but one attended the 2024 Annual Meeting .
  • Leadership structure: Controlled company (GNI Japan controls a majority); Chair and CEO roles separated; Chair is not independent; no Lead Independent Director designated; independent directors meet in executive session at every regular Board meeting .
  • Compensation Committee independence: Company elected not to use controlled company exemption; all Compensation Committee members are independent and satisfy Rule 10C .

Fixed Compensation

YearFees Earned or Paid in Cash ($)Committee Chair/Member Fees Included?Total Cash ($)
2023$7,500 Program provided annual retainers; 2023 service partial year post-merger $7,500
2024$57,167 Includes Board retainer and Nominating Chair fee; 2024 program shows Board Member $40,000 and Nominating Chair $10,000 $57,167
  • Non-employee director cash retainer schedule (as of 2025 proxy): Board Chair $75,000; non-Chair Board member $40,000; Audit Chair $18,000, member $9,000; Compensation Chair $14,000, member $7,000; Nominating Chair $10,000, member $5,000 .

Performance Compensation

YearEquity InstrumentGrant Details (shares/options)Grant DateFair Value ($)Vesting Schedule
2023Stock options (initial + special)1,866 initial; 341,652 Business Combination recognition; total referenced in footnoteOct 2023 $1,872,169 Initial option grants vest monthly over 3 years; 2023 annual grants vest monthly over 1 year or until next annual meeting
2024Stock options (annual)Outstanding options at 12/31: 369,518; prior year 343,518; change +26,000 consistent with annual grant2024 Annual Meeting cycle $191,436 Annual stock option grants vest in equal monthly installments over one year
  • 2025 director equity program: initial grant 52,000 options vesting monthly over 3 years; annual grant 26,000 options vesting monthly over 1 year .

Other Directorships & Interlocks

EntityRelationship to GyreEastling’s RolePotential Interlock/Conflict
GNI Group Ltd. (GNI Japan)Controls majority of Gyre voting power via affiliatesOutside member; Advisor to Executive CommitteeGovernance influence risk; nomination dynamics as controlled company
Cullgen Inc.Separate biopharmaCFO and DirectorOverlapping industry exposure; director time commitments

Expertise & Qualifications

  • Financial, global finance, and M&A expertise; senior postings in NY, London, Tokyo, Hong Kong; CFO experience at GNI Japan and Cullgen .
  • Education: BA from University of Southern California; master’s from American Graduate School of International Management .
  • Governance credentials: Graduated from Board Director Training Institute of Japan; NACD.DC Certified Director .

Equity Ownership

HolderForm of OwnershipAmount% of OutstandingNotes
Thomas EastlingOptions exercisable within 60 days359,607 Part of 1.0% totalAs of March 12, 2025
Spouse (Ruoyu Chen) attributed to EastlingOptions exercisable within 60 days612,920 Included in Eastling lineBeneficial attribution due to marriage
Thomas Eastling total (incl. spouse-attributed)Beneficial ownership972,527 1.0% No direct share count disclosed; entirely options within 60 days
  • Anti-hedging: Directors, officers, employees prohibited from short-term trading, short sales, options/derivatives trading in Company securities, and hedging transactions .
  • Ownership guidelines: Not disclosed in proxy; no director ownership guideline details provided .

Board Governance Signals and Compensation Structure Analysis

  • Controlled company governance: Gyre relies on Nasdaq controlled company exemptions; Board does not have a majority of independent directors; director nominees are not selected entirely by independent directors .
  • Independence and conflicts: Eastling is not independent due to spousal relationship with CFO; also holds roles at GNI Japan (controlling shareholder), elevating potential influence and information-flow interlocks; he chairs Nominating despite non-independence—material governance risk .
  • Committee quality: Audit and Compensation Committees are fully independent and comply with SEC/Nasdaq independence criteria; Compensation Committee employed Aon/Radford in 2024 .
  • Attendance: Board met four times; ≥75% attendance for all directors; Nominating met once in 2024 .
  • Director pay mix shift: Eastling’s option award value dropped from $1,872,169 (2023, reflecting Business Combination grants) to $191,436 (2024), with cash rising to $57,167—normalization of equity compensation post-merger .
  • Equity plan and clawback: 2023 Omnibus Incentive Plan administers options; Incentive Compensation Clawback Policy compliant with Nasdaq Listing Standard 5608 .

Say-on-Pay & Shareholder Feedback

ProposalVotes ForVotes AgainstAbstentionsBroker Non-Votes
2025 Say-on-Pay69,505,961 39,318 1,936 2,778,540
  • Frequency: Gyre holds say-on-pay annually; next advisory vote expected in 2026 per Board policy .
  • Auditor ratification 2025: 72,175,754 For; 3,738 Against; 146,263 Abstentions .

Related Party Transactions

  • R&D services: $0.2 million paid to GNI Japan in 2024; related parties payable $0.2 million at 12/31/2024 .
  • Receivables: CPI restructuring and other receivables from GNI Japan—$0.2 million recorded at 12/31/2024 (incl. CPI restructuring), down from $1.3 million at 12/31/2023 (including $0.8 million CPI restructuring and $0.5 million Business Combination cost sharing) .
  • Policy: Audit Committee reviews and approves related-person transactions >$120k; conflicted directors excluded from deliberations/votes .

Governance Assessment

  • Strengths: Independent Audit and Compensation Committees; formal clawback and anti-hedging policies; regular executive sessions of independent directors; strong say-on-pay support in 2025 .
  • Risks/RED FLAGS:
    • Not independent: Eastling’s marital tie to CFO disqualifies independence; he still chairs Nominating—elevated entrenchment risk in director succession and nomination process .
    • Controlled company structure: Majority control by GNI Japan; nominations not fully led by independent directors—potential for shareholder-unfriendly governance decisions .
    • Interlocks: Eastling’s ongoing roles with GNI Japan (controller) and Cullgen may create information-flow or prioritization conflicts; continued monitoring warranted .
  • Alignment: Eastling’s beneficial ownership is entirely via options (including spouse-attributed), totaling 1.0%—provides some alignment, but absence of direct share ownership and hedging prohibition suggests guardrails; no ownership guideline disclosure for directors .