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HARVARD BIOSCIENCE INC (HBIO)·Q1 2025 Earnings Summary

Executive Summary

  • Q1 2025 revenue was $21.8M, above S&P Global consensus $19.2M; adjusted diluted EPS came in at $(0.01) vs consensus $(0.04), representing modest beats on both top-line and adjusted EPS. Gross margin declined to 56.0% (from 60.3% YoY) on lower volume and fixed-cost absorption; GAAP EPS was $(1.14) driven by a $48.0M non-cash goodwill impairment . Consensus numbers: Revenue $19.2M, EPS $(0.04)*.
  • Management guided Q2 2025 revenue to $18–$20M and gross margin to 55%–57%, implying sequential softening tied to China tariff impacts and NIH funding uncertainty; operating cost actions are expected to reduce OpEx by ~$1M per quarter starting Q2 .
  • The call emphasized early momentum in MeshMEA organoid systems (academic/bio­pharma adoption) and SoHo telemetry platform, plus progress in BTX electroporation for bioproduction (consumables ~$1M run-rate with a top-5 pharma customer), supporting medium-term growth and recurring revenue mix .
  • Liquidity improved with $3.0M operating cash flow and net debt down to $30.8M; management is pursuing a debt refinancing expected to close per amendment timing (~4–5 year tenor; “more expensive than commercial debt”) .

What Went Well and What Went Wrong

What Went Well

  • Revenue and adjusted EPS beat light consensus: $21.8M actual vs $19.2M consensus; adjusted diluted EPS $(0.01) vs $(0.04) consensus, as cost actions helped offset lower volumes *.
  • Operating cash flow improved to $3.0M vs $1.4M YoY; net debt fell to $30.8M from $33.2M at year-end, aided by disciplined working capital .
  • Early product traction: “emerging adoption of our breakthrough MeshMEA organoid systems... [and] market reception of our new SoHo telemetry systems” (CEO) with academic, CRO, and biopharma customers; BTX consumables reached ~$1M annual run-rate with a top-5 pharma, and a CAR-T bioproduction opportunity with a U.S. biotech .

What Went Wrong

  • Gross margin compressed to 56.0% from 60.3% YoY due to lower fixed cost absorption and prior-year accounting benefit of ~1.6 points; adjusted EBITDA declined to $0.8M vs $1.6M YoY .
  • GAAP net loss of $(50.3)M and GAAP EPS $(1.14) were dominated by a non-cash goodwill impairment charge of $48.0M triggered by market cap decline; operating loss widened accordingly .
  • Regional demand headwinds: Europe down 29% sequentially, Americas down 5.4% sequentially, APAC down 17% YoY with tariff-related softening expected in Q2; NIH purchasing uncertainty slowed academic buying cycles .

Financial Results

MetricQ3 2024Q4 2024Q1 2025
Revenue ($USD Millions)$22.0 $24.6 $21.8
Gross Margin %58.1% 57.1% 56.0%
Adjusted EBITDA ($USD Millions)$1.31 $2.99 $0.81
GAAP Net Income (Loss) ($USD Millions)$(4.80) $0.02 $(50.34)
Diluted EPS (GAAP) ($USD)$(0.11) $0.00 $(1.14)
Diluted Adjusted EPS ($USD)$(0.02) $0.06 $(0.01)
Cash from Operations ($USD Millions)$(0.84) $1.73 $2.99
Net Debt ($USD Millions)$33.78 $33.24 $30.80

Segment/Region trends (Q1 2025):

RegionSequential Change vs Q4 2024YoY Change vs Q1 2024
Americas-5.4% -9.4%
Europe-29% -9%
APAC+6.6% -17%

Key KPIs (Q1 2025):

KPIQ1 2025 Value
Goodwill Impairment ($USD Millions)$47.95
Total Operating Expenses ($USD Millions)$61.85
Adjusted Operating Margin1.5%
Cash and Equivalents ($USD Millions)$5.55
Debt ($USD Millions)$35.96

Guidance Changes

MetricPeriodPrevious GuidanceCurrent GuidanceChange
RevenueQ1 2025$19M–$21M Actual: $21.8M Met at high end
Gross Margin %Q1 202556%–58% Actual: 56.0% In range (low end)
RevenueQ2 2025$18M–$20M New guidance (lower seq)
Gross Margin %Q2 202555%–57% New guidance (lower seq)
OpEx Run-Rate ReductionStarting Q4 2024~$1M/quarter beginning Q4 ~$1M/quarter beginning Q2 2025 Maintained magnitude; timing reiterated

Earnings Call Themes & Trends

TopicPrevious Mentions (Q3 2024)Previous Mentions (Q4 2024)Current Period (Q1 2025)Trend
NIH/Academic FundingStabilizing orders; CRO tightness; academic budgets tight Expect dip in Q1; academic “end-of-year bump” absent NIH uncertainty; purchasing slowed by staffing changes Pressure persists
China/APAC Tariffs/MacroAPAC weakness; expect stabilization APAC sequential improvement Q4; still down YoY APAC up 6.6% seq; tariff announcements caused softening in Q2 outlook Mixed; tariff headwind
ERP ConsolidationU.S. ERP unified; expected efficiencies Sequential margin stability; some inefficiencies; benefits expected in 2025 Continued ramp; margin gains anticipated later in year Execution ongoing
New Products (MeshMEA, SoHo, VivaMARS)Beta sites; initial shipments; up to 10 systems by Q4 10+ systems placed; strong interest; distributors expanding U.S. reach Adoption expanding; MeshMEA momentum; SoHo expanding to cardiac/neuro Positive adoption
BTX Electroporation/BioproductionTop pharma consumables ~$1M run-rate; CGMP AAA shipped Top-5 pharma vaccine; Novo Nordisk, CAR-T opportunity CAR-T domestic use case; strategy vs MaxCyte; recurring revenue focus Building pipeline
Refinancing/LeverageCredit agreement constraints; plan to refinance by March 2025 Amendment waiver; refinance by June 30; no revolver draws Multiple proposals; 4–5 year tenor; higher than commercial rates Progressing

Management Commentary

  • CEO on demand outlook and product traction: “We are excited by the emerging adoption of our breakthrough MeshMEA™ organoid systems... and encouraged by the market reception of our new SoHo™ telemetry systems.”
  • Interim CFO on impairment: “Due primarily to the decrease in our market capitalization in quarter 1, we performed additional impairment testing… [resulting in] a noncash goodwill impairment charge of $48 million.”
  • CEO on tariffs: “We were coming into this thinking… a $2 million a quarter kind of headwind. Hopefully, that’s not the case now” after U.S.-China news; China ~10% of revenue .
  • Product pipeline: MeshMEA “first in vitro… capable of monitoring neuro and cardiac organoids over much longer time periods measured in months, not days,” with early adopters Stanford and Mayo Clinic; BTX AgilePulse widely referenced in CAR-T literature .
  • Distribution expansion: extending Fisher/VWR distribution to North America to boost MeshMEA reach .

Q&A Highlights

  • Refinancing: Rate will be “more expensive than commercial debt”; tenor “4–5 years” with details pending negotiations .
  • CAR-T bioproduction: Domestic biotech adopting BTX for CAR-T bioproduction; AgilePulse cited broadly in peer-reviewed CAR-T research .
  • MeshMEA demand vs NIH: Strong inbound interest; NIH budgets exist but purchasing slowed by reductions in procurement staff; funnel growing despite longer cycles .
  • Competitive positioning vs MaxCyte: HBIO targeting earlier-stage adopters and razor/razorblade consumable model; high-volume would require further investment .
  • Impairment rationale: DCF reconciled to market cap triggered non-cash goodwill impairment of $48M in Q1 .

Estimates Context

MetricQ1 2025 ConsensusQ1 2025 Actual
Revenue ($USD)$19,200,000*$21,774,000
Primary EPS ($USD)$(0.04)*$(0.01)*
EBITDA ($USD)$(1,000,000)*$31,000*

Values retrieved from S&P Global. Coverage is thin (2 estimates for revenue and EPS)*. Actual adjusted EBITDA reported by the company was $0.814M ; S&P EBITDA figures may reflect a different basis.

Implications: modest top-line and adjusted EPS beats; estimate models likely need to reflect lower Q2 guide, margin compression from volume/mix, and non-GAAP add-backs vs GAAP impairment.

Key Takeaways for Investors

  • Results beat light consensus on revenue and adjusted EPS; however, margin headwinds and a large non-cash goodwill impairment dominated GAAP results—focus on cash generation and adjusted metrics for near-term assessment *.
  • Near-term guide is conservative (Q2 revenue $18–$20M; GM 55%–57%) due to China tariffs and NIH-related purchasing delays; expect sequential softness before new product contribution and cost reductions aid H2 trajectory .
  • Execution on MeshMEA and SoHo can shift mix toward recurring consumables and support multi-year growth; BTX bioproduction consumables already at ~$1M run-rate with a top-5 pharma, with CAR-T opportunity as an upside lever .
  • Liquidity posture improving: $3.0M CFO, net debt down to $30.8M; watch refinancing terms and timing by June 30 as a key catalyst/overhang .
  • Academic demand should normalize as NIH purchasing bottlenecks resolve; distribution expansion (Fisher/VWR in North America) could accelerate MeshMEA pipeline conversion .
  • Trading lens: beats vs light estimates are tempered by macro headwinds and GAAP impairment; stock may be sensitive to refinancing announcements, tariff developments in China, and incremental MeshMEA/BTX commercial milestones .

*All consensus estimate values are retrieved from S&P Global.