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Kaouthar Lbiati

Interim Chief Executive Officer and Interim Chief Financial Officer at Hepion PharmaceuticalsHepion Pharmaceuticals
CEO
Executive
Board

About Kaouthar Lbiati

Dr. Kaouthar Lbiati is Interim Chief Executive Officer of Hepion Pharmaceuticals effective June 16, 2025, under an initial three‑month term; her annual base salary is $350,000 with $50,000 deferred until the earlier of a ≥$3 million equity financing, her departure, or a change in control, and she is eligible for a performance bonus equal to 35% of base contingent on mutually agreed milestones; if terminated without cause before term end, a pro‑rated bonus may be payable . She has served on Hepion’s Board since June 2022 and, as of April 24, 2025, was 47 years old; her background spans strategy and launches at Amgen, GSK, Sanofi, and leadership roles at Cytovia Therapeutics; education includes an M.D. (Mohammed V University), oncology fellowship (Gustave Roussy), executive master’s (ESSEC), and an M.S. (LSE), with corporate governance (Columbia) and finance (Harvard) certifications in 2022 . She also serves on the board of Theralase Technologies and is leading Hepion’s strategic repositioning toward precision diagnostics in celiac disease, respiratory multiplex testing, H. pylori, and HCC . As of the February 2025 proxy, the Board classified Dr. Lbiati as independent; upon assuming the executive role, typical practice is that independence status is suspended while serving as an officer (the filing does not separately restate independence post‑appointment) .

Past Roles

OrganizationRoleYearsStrategic Impact
Cytovia TherapeuticsAdvisor to CEO (May 2020, 3 months); VP Product Strategy (to Jul 2021); VP Strategy & Corporate Development (to Nov 2022)2020–2022Helped optimize platform, prioritize pipeline, and position company with investors and partners .
Amgen; GlaxoSmithKline; SanofiGlobal/regional leadership roles~10+ years (prior decade)Supported registration, launch/indication extensions, and reimbursement for Blincyto, Jevtana, Votrient across U.S./EU/MENA; medical affairs, HEOR, market access .
Consulting to early/late‑stage biotechsStrategy advisor (e.g., Steba, Immune Pharmaceuticals)Since Nov 2017Corporate strategy, portfolio growth, funding readiness and deal execution .

External Roles

OrganizationRoleYearsNotes
Theralase Technologies Inc.DirectorCurrent (as of Jun 2025)Clinical‑stage oncology company; concurrent board service noted by Hepion .

Fixed Compensation

ComponentTermsPeriod/Notes
Base Salary (Interim CEO)$350,000 annualized; $50,000 deferred until earlier of ≥$3M equity financing, departure, or change in controlInitial 3‑month term effective Jun 16, 2025 .

Performance Compensation

Metric/InstrumentWeighting/TargetActual/PayoutVesting/Notes
Cash bonus (Interim CEO)Target 35% of base; milestones mutually agreedNot disclosed; pro‑rata bonus if terminated without cause before term endApplies to 3‑month interim term starting Jun 16, 2025 .

Equity award design context: Hepion’s equity plans provide for stock options/RSUs, with options generally vesting annually over four years and 10‑year terms once vested; clawback provisions apply to executives for restatements per the 2023 Omnibus Equity Incentive Plan .

Director Compensation

YearCash Fees ($)Equity/Option Awards ($)Total ($)
202485,543 188,424 273,967
202375,375 0 75,375
2022 (partial)30,923 0 30,923

Committee fee schedule (non‑employee directors, 2022 framework): $60,000 annual board retainer; chairs: Audit $11,000, Compensation $8,000, Nominating/Gov $6,400; members: Audit $6,000, Compensation $6,500, Nominating/Gov $3,500 .

Equity Ownership & Alignment

As‑Of DateBeneficial Ownership DetailAmount% Outstanding
Dec 31, 2024Options exercisable within 60 days (pre‑split figures)87,000 <1%
Apr 24, 2025 (Record Date)Options exercisable within 60 days (post 1‑for‑50 reverse split)1,760 <1%
Dec 31, 2024 (breakdown)Options outstanding (of which exercisable)1,760 (1,740 exercisable) n/a
  • Ownership guidelines: Company encourages equity ownership but discloses no specific share retention/ownership guidelines for executives outside of its equity plan .
  • Pledging/hedging: Plan restricts transfers/pledges of awards without prior written consent; no separate anti‑hedging policy disclosed in the cited materials .
  • Reverse split mechanics: On March 17, 2025, Hepion effected a 1‑for‑50 reverse split; option share counts and strikes were adjusted proportionally .

Employment Terms

  • Appointment: Interim CEO effective June 16, 2025; initial term three months .
  • Compensation: $350,000 annual base; $50,000 of base deferred until earlier of ≥$3M equity financing, her departure, or a change in control; eligible for 35% target bonus tied to mutually agreed milestones; pro‑rated bonus if terminated without cause before term end .
  • Severance/CoC: Beyond the pro‑rata bonus clause and deferred salary triggers, no additional severance or CoC multipliers specific to Dr. Lbiati are disclosed in the cited filings .
  • Clawback: Executive incentive compensation subject to recoupment in event of accounting restatements under the 2023 plan and applicable rules .

Board Governance

  • Service history: Director since June 2022; nominated for continued board service in 2025 proxy .
  • Committee roles:
    • Audit Committee member; 2025 Audit Committee Report lists Purcell (Chair), Lbiati, Block .
    • Corporate Governance/Nominating Committee member; Block (Chair), Lbiati, Purcell .
    • 2023 proxy also listed her as an Audit Committee member .
  • Attendance: In 2023, Board met 11 times; Audit 4; Compensation 6; Nominating/Gov 2; all directors and committee members had 100% attendance .
  • Independence: As of the Feb 7, 2025 proxy, Board considered Drs. Block and Lbiati and Mr. Purcell independent under Nasdaq rules; independence status typically ceases while serving as an executive (post‑June 16, 2025) .
  • Dual‑role note: She is both director and Interim CEO; on June 30, 2025, she signed an 8‑K as Interim Chief Financial Officer following the CFO/director resignation, indicating temporary assumption of additional officer responsibilities for filing purposes .

Performance Compensation (Director Equity Grants)

YearInstrumentGrant Date/Fair ValueVesting Notes
2024Options/RSUs$188,424 fair valuePlan‑based equity; individual award vesting schedules not specified in proxy; company plan generally uses multi‑year vesting .
2023Options$0 (no grants)No equity awards to non‑employee directors in 2023 .

Governance Policies Relevant to Pay Alignment

  • Equity plan design and vesting: Options/RSUs under the 2013 and 2023 plans; options generally vest annually over four years and are exercisable up to 10 years once vested, aligning value with stock appreciation .
  • Clawback: Three‑year lookback for executive incentive compensation upon financial restatements, irrespective of fault, with recoupment in cash or equity forfeiture per committee discretion .
  • Ownership guidelines: No specific executive share ownership/retention guidelines beyond equity plans; encourages, but does not mandate, holdings .

Track Record, Achievements, and Context

  • Strategic pivot: Under her leadership appointment announcement, Hepion emphasized repositioning to precision diagnostics and near‑term revenue generation via CE‑marked tests in Europe/UK and U.S. submissions .
  • Corporate actions context: Reverse stock split 1‑for‑50 announced March 14, 2025 and effective March 17, 2025, intended to regain Nasdaq minimum bid compliance; options/warrants adjusted proportionally .
  • Background: Led or contributed to multiple therapy launches (Jevtana, Votrient, Blincyto, Filgotinib, Symbicort) across oncology/respiratory/immunology markets .

Risk Indicators & Red Flags

  • Listing/price risk context: Reverse split to address compliance with Nasdaq minimum bid requirement; mechanical adjustments to equity awards may affect optics of equity holdings and potential liquidity events .
  • Dual‑hat governance risk: Interim CEO while also a director (and signed as Interim CFO on 6/30/25 filing), which may raise independence/oversight considerations until permanent roles are set .
  • Clawback coverage: Robust restatement‑based clawback reduces windfall risk from misstated results .
  • Ownership alignment: Beneficial ownership consists primarily of options; direct common stock ownership not disclosed in 2024–2025 tables for Dr. Lbiati, and stake is <1% .

Compensation Structure Analysis

  • Mix shift: Non‑employee director compensation for Dr. Lbiati increased equity component materially in 2024 ($188,424 fair value) versus zero equity in 2023, signaling stronger equity‑based alignment that year .
  • Interim CEO pay design: High at‑risk component via milestone‑based 35% bonus and cash‑preservation via $50k deferred salary contingent on financing/change‑in‑control suggests near‑term liquidity sensitivity and performance‑linked cash outflow .
  • Ownership requirements: Absence of explicit executive ownership guidelines may limit enforced “skin‑in‑the‑game,” though options align upside with shareholders .

Equity Ownership & Beneficial Holdings Detail

Date ReferenceShares/OptionsNotes
Dec 31, 202487,000 options exercisable within 60 days (pre‑split) Less than 1% ownership .
Dec 31, 20241,760 options outstanding; 1,740 exercisable (post‑split presentation) Post‑split disclosure reconciliation.
Apr 24, 20251,760 options exercisable within 60 days (post‑split) Less than 1% ownership .

Employment & Contracts (Key Economics)

TermProvisionSource
AppointmentInterim CEO from Jun 16, 2025; term 3 months
Base Salary$350,000 annual; $50,000 deferred until ≥$3M equity financing or departure/CoC
Bonus Target35% of base; milestones mutually agreed; pro‑rated if terminated without cause before term end
Clawback3‑year lookback for executive incentive recoupment on restatement

Board Service Summary and Independence

  • Committees: Audit (member; 2025 Audit Committee Report: Purcell, Chair; Lbiati; Block) and Nominating/Corporate Governance (member; Block, Chair; Lbiati; Purcell) .
  • Attendance: 100% meeting attendance for Board and committees in 2023 .
  • Independence: Independent as of Feb 7, 2025 proxy; independence changes upon executive appointment Jun 2025 (not separately re‑stated in filings) .
  • Director election: Nominated for 2025 annual meeting slate .

Investment Implications

  • Alignment and liquidity: Dr. Lbiati’s economic exposure at Hepion currently skews to options rather than direct share ownership, and the 1‑for‑50 reverse split compresses counts while preserving proportional exposure; watch for any new executive equity awards and Form 4 activity post‑appointment to gauge selling pressure/retention signals .
  • Near‑term catalysts/risks: Interim CEO term and milestone‑based bonus design suggest a focus on financing (>=$3M trigger tied to deferred salary) and execution of the diagnostics pivot; financing outcomes and regulatory/commercial milestones may directly influence cash compensation realization and retention .
  • Governance watchpoints: Dual‑role dynamics (Interim CEO and director; signed as Interim CFO on 6/30/25 8‑K) elevate oversight considerations until permanent appointments are made; committee membership and attendance history support engagement, but independence status is suspended during executive service .
  • Policy backstops: Clawback and transfer/pledge restrictions on awards mitigate certain governance risks, but absence of formal stock ownership guidelines may limit enforced alignment during a critical strategic transition .