Kaouthar Lbiati
About Kaouthar Lbiati
Dr. Kaouthar Lbiati is Interim Chief Executive Officer of Hepion Pharmaceuticals effective June 16, 2025, under an initial three‑month term; her annual base salary is $350,000 with $50,000 deferred until the earlier of a ≥$3 million equity financing, her departure, or a change in control, and she is eligible for a performance bonus equal to 35% of base contingent on mutually agreed milestones; if terminated without cause before term end, a pro‑rated bonus may be payable . She has served on Hepion’s Board since June 2022 and, as of April 24, 2025, was 47 years old; her background spans strategy and launches at Amgen, GSK, Sanofi, and leadership roles at Cytovia Therapeutics; education includes an M.D. (Mohammed V University), oncology fellowship (Gustave Roussy), executive master’s (ESSEC), and an M.S. (LSE), with corporate governance (Columbia) and finance (Harvard) certifications in 2022 . She also serves on the board of Theralase Technologies and is leading Hepion’s strategic repositioning toward precision diagnostics in celiac disease, respiratory multiplex testing, H. pylori, and HCC . As of the February 2025 proxy, the Board classified Dr. Lbiati as independent; upon assuming the executive role, typical practice is that independence status is suspended while serving as an officer (the filing does not separately restate independence post‑appointment) .
Past Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| Cytovia Therapeutics | Advisor to CEO (May 2020, 3 months); VP Product Strategy (to Jul 2021); VP Strategy & Corporate Development (to Nov 2022) | 2020–2022 | Helped optimize platform, prioritize pipeline, and position company with investors and partners . |
| Amgen; GlaxoSmithKline; Sanofi | Global/regional leadership roles | ~10+ years (prior decade) | Supported registration, launch/indication extensions, and reimbursement for Blincyto, Jevtana, Votrient across U.S./EU/MENA; medical affairs, HEOR, market access . |
| Consulting to early/late‑stage biotechs | Strategy advisor (e.g., Steba, Immune Pharmaceuticals) | Since Nov 2017 | Corporate strategy, portfolio growth, funding readiness and deal execution . |
External Roles
| Organization | Role | Years | Notes |
|---|---|---|---|
| Theralase Technologies Inc. | Director | Current (as of Jun 2025) | Clinical‑stage oncology company; concurrent board service noted by Hepion . |
Fixed Compensation
| Component | Terms | Period/Notes |
|---|---|---|
| Base Salary (Interim CEO) | $350,000 annualized; $50,000 deferred until earlier of ≥$3M equity financing, departure, or change in control | Initial 3‑month term effective Jun 16, 2025 . |
Performance Compensation
| Metric/Instrument | Weighting/Target | Actual/Payout | Vesting/Notes |
|---|---|---|---|
| Cash bonus (Interim CEO) | Target 35% of base; milestones mutually agreed | Not disclosed; pro‑rata bonus if terminated without cause before term end | Applies to 3‑month interim term starting Jun 16, 2025 . |
Equity award design context: Hepion’s equity plans provide for stock options/RSUs, with options generally vesting annually over four years and 10‑year terms once vested; clawback provisions apply to executives for restatements per the 2023 Omnibus Equity Incentive Plan .
Director Compensation
| Year | Cash Fees ($) | Equity/Option Awards ($) | Total ($) |
|---|---|---|---|
| 2024 | 85,543 | 188,424 | 273,967 |
| 2023 | 75,375 | 0 | 75,375 |
| 2022 (partial) | 30,923 | 0 | 30,923 |
Committee fee schedule (non‑employee directors, 2022 framework): $60,000 annual board retainer; chairs: Audit $11,000, Compensation $8,000, Nominating/Gov $6,400; members: Audit $6,000, Compensation $6,500, Nominating/Gov $3,500 .
Equity Ownership & Alignment
| As‑Of Date | Beneficial Ownership Detail | Amount | % Outstanding |
|---|---|---|---|
| Dec 31, 2024 | Options exercisable within 60 days (pre‑split figures) | 87,000 | <1% |
| Apr 24, 2025 (Record Date) | Options exercisable within 60 days (post 1‑for‑50 reverse split) | 1,760 | <1% |
| Dec 31, 2024 (breakdown) | Options outstanding (of which exercisable) | 1,760 (1,740 exercisable) | n/a |
- Ownership guidelines: Company encourages equity ownership but discloses no specific share retention/ownership guidelines for executives outside of its equity plan .
- Pledging/hedging: Plan restricts transfers/pledges of awards without prior written consent; no separate anti‑hedging policy disclosed in the cited materials .
- Reverse split mechanics: On March 17, 2025, Hepion effected a 1‑for‑50 reverse split; option share counts and strikes were adjusted proportionally .
Employment Terms
- Appointment: Interim CEO effective June 16, 2025; initial term three months .
- Compensation: $350,000 annual base; $50,000 of base deferred until earlier of ≥$3M equity financing, her departure, or a change in control; eligible for 35% target bonus tied to mutually agreed milestones; pro‑rated bonus if terminated without cause before term end .
- Severance/CoC: Beyond the pro‑rata bonus clause and deferred salary triggers, no additional severance or CoC multipliers specific to Dr. Lbiati are disclosed in the cited filings .
- Clawback: Executive incentive compensation subject to recoupment in event of accounting restatements under the 2023 plan and applicable rules .
Board Governance
- Service history: Director since June 2022; nominated for continued board service in 2025 proxy .
- Committee roles:
- Audit Committee member; 2025 Audit Committee Report lists Purcell (Chair), Lbiati, Block .
- Corporate Governance/Nominating Committee member; Block (Chair), Lbiati, Purcell .
- 2023 proxy also listed her as an Audit Committee member .
- Attendance: In 2023, Board met 11 times; Audit 4; Compensation 6; Nominating/Gov 2; all directors and committee members had 100% attendance .
- Independence: As of the Feb 7, 2025 proxy, Board considered Drs. Block and Lbiati and Mr. Purcell independent under Nasdaq rules; independence status typically ceases while serving as an executive (post‑June 16, 2025) .
- Dual‑role note: She is both director and Interim CEO; on June 30, 2025, she signed an 8‑K as Interim Chief Financial Officer following the CFO/director resignation, indicating temporary assumption of additional officer responsibilities for filing purposes .
Performance Compensation (Director Equity Grants)
| Year | Instrument | Grant Date/Fair Value | Vesting Notes |
|---|---|---|---|
| 2024 | Options/RSUs | $188,424 fair value | Plan‑based equity; individual award vesting schedules not specified in proxy; company plan generally uses multi‑year vesting . |
| 2023 | Options | $0 (no grants) | No equity awards to non‑employee directors in 2023 . |
Governance Policies Relevant to Pay Alignment
- Equity plan design and vesting: Options/RSUs under the 2013 and 2023 plans; options generally vest annually over four years and are exercisable up to 10 years once vested, aligning value with stock appreciation .
- Clawback: Three‑year lookback for executive incentive compensation upon financial restatements, irrespective of fault, with recoupment in cash or equity forfeiture per committee discretion .
- Ownership guidelines: No specific executive share ownership/retention guidelines beyond equity plans; encourages, but does not mandate, holdings .
Track Record, Achievements, and Context
- Strategic pivot: Under her leadership appointment announcement, Hepion emphasized repositioning to precision diagnostics and near‑term revenue generation via CE‑marked tests in Europe/UK and U.S. submissions .
- Corporate actions context: Reverse stock split 1‑for‑50 announced March 14, 2025 and effective March 17, 2025, intended to regain Nasdaq minimum bid compliance; options/warrants adjusted proportionally .
- Background: Led or contributed to multiple therapy launches (Jevtana, Votrient, Blincyto, Filgotinib, Symbicort) across oncology/respiratory/immunology markets .
Risk Indicators & Red Flags
- Listing/price risk context: Reverse split to address compliance with Nasdaq minimum bid requirement; mechanical adjustments to equity awards may affect optics of equity holdings and potential liquidity events .
- Dual‑hat governance risk: Interim CEO while also a director (and signed as Interim CFO on 6/30/25 filing), which may raise independence/oversight considerations until permanent roles are set .
- Clawback coverage: Robust restatement‑based clawback reduces windfall risk from misstated results .
- Ownership alignment: Beneficial ownership consists primarily of options; direct common stock ownership not disclosed in 2024–2025 tables for Dr. Lbiati, and stake is <1% .
Compensation Structure Analysis
- Mix shift: Non‑employee director compensation for Dr. Lbiati increased equity component materially in 2024 ($188,424 fair value) versus zero equity in 2023, signaling stronger equity‑based alignment that year .
- Interim CEO pay design: High at‑risk component via milestone‑based 35% bonus and cash‑preservation via $50k deferred salary contingent on financing/change‑in‑control suggests near‑term liquidity sensitivity and performance‑linked cash outflow .
- Ownership requirements: Absence of explicit executive ownership guidelines may limit enforced “skin‑in‑the‑game,” though options align upside with shareholders .
Equity Ownership & Beneficial Holdings Detail
| Date Reference | Shares/Options | Notes |
|---|---|---|
| Dec 31, 2024 | 87,000 options exercisable within 60 days (pre‑split) | Less than 1% ownership . |
| Dec 31, 2024 | 1,760 options outstanding; 1,740 exercisable (post‑split presentation) | Post‑split disclosure reconciliation. |
| Apr 24, 2025 | 1,760 options exercisable within 60 days (post‑split) | Less than 1% ownership . |
Employment & Contracts (Key Economics)
| Term | Provision | Source |
|---|---|---|
| Appointment | Interim CEO from Jun 16, 2025; term 3 months | |
| Base Salary | $350,000 annual; $50,000 deferred until ≥$3M equity financing or departure/CoC | |
| Bonus Target | 35% of base; milestones mutually agreed; pro‑rated if terminated without cause before term end | |
| Clawback | 3‑year lookback for executive incentive recoupment on restatement |
Board Service Summary and Independence
- Committees: Audit (member; 2025 Audit Committee Report: Purcell, Chair; Lbiati; Block) and Nominating/Corporate Governance (member; Block, Chair; Lbiati; Purcell) .
- Attendance: 100% meeting attendance for Board and committees in 2023 .
- Independence: Independent as of Feb 7, 2025 proxy; independence changes upon executive appointment Jun 2025 (not separately re‑stated in filings) .
- Director election: Nominated for 2025 annual meeting slate .
Investment Implications
- Alignment and liquidity: Dr. Lbiati’s economic exposure at Hepion currently skews to options rather than direct share ownership, and the 1‑for‑50 reverse split compresses counts while preserving proportional exposure; watch for any new executive equity awards and Form 4 activity post‑appointment to gauge selling pressure/retention signals .
- Near‑term catalysts/risks: Interim CEO term and milestone‑based bonus design suggest a focus on financing (>=$3M trigger tied to deferred salary) and execution of the diagnostics pivot; financing outcomes and regulatory/commercial milestones may directly influence cash compensation realization and retention .
- Governance watchpoints: Dual‑role dynamics (Interim CEO and director; signed as Interim CFO on 6/30/25 8‑K) elevate oversight considerations until permanent appointments are made; committee membership and attendance history support engagement, but independence status is suspended during executive service .
- Policy backstops: Clawback and transfer/pledge restrictions on awards mitigate certain governance risks, but absence of formal stock ownership guidelines may limit enforced alignment during a critical strategic transition .