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Isaac Barchas

Lead Independent Director at Immunome
Board

About Isaac Barchas

Isaac Barchas, J.D., age 57, has served as Immunome’s lead independent director since October 2023 and as a Class II director since 2023. He holds a B.A. from Stanford University and an M.A. and J.D. from the University of Chicago. His background includes leadership at Research Bridge Partners (board member since 2017; CEO through January 2024), Director of the Austin Technology Incubator (2006–2016), and consulting at McKinsey & Company (1996–2006). He also serves on the board of Tetricus Labs, a private AI-enabled psychiatric diagnostics company.

Past Roles

OrganizationRoleTenureCommittees/Impact
Research Bridge PartnersPresident & CEO; DirectorJan 2017–Jan 2024 (CEO); Director since Jan 2017Led biotech acceleration; remains on board
Austin Technology IncubatorDirector2006–2016Directed incubation program; innovation ecosystem
McKinsey & CompanyConsultant1996–2006Strategy/operations advisory experience

External Roles

OrganizationRoleTenureCommittees/Impact
Research Bridge PartnersDirectorJan 2017–presentGovernance oversight at biotech accelerator
Tetricus Labs (private)DirectorCurrentAI-enabled psychiatric diagnostics focus

Board Governance

  • Current roles: Lead Independent Director; Chair, Nominating & Corporate Governance Committee; Member, Compensation Committee.
  • Independence: Board affirmatively determined Barchas is independent under Nasdaq and SEC rules (general board and compensation committee standards).
  • Lead Independent Director responsibilities: presides over meetings in Chair’s absence, liaises between Chair and independent directors, presides over independent director sessions, and consults on board agendas/schedules.
  • Attendance and engagement: In 2024, Board met 8x; Committees met Audit 4x, Compensation 6x, Nominating 4x; no director attended fewer than 75% of applicable meetings. Executive sessions of independent directors are held regularly (typically at each regular Board meeting).
CommitteeMembershipChairIndependence/Notes
Nominating & Corporate GovernanceBarchas, Boylan, SchaferBarchasAll members independent; oversees board independence, conflicts, succession, and board effectiveness
CompensationBoylan, Barchas, BienaiméBoylanAll independent; oversees exec/dir compensation, clawbacks, equity plans
AuditSchafer, Bienaimé, SwainSchaferNot a member; all members independent; Schafer is audit committee financial expert

Fixed Compensation

Component (FY2024)Amount (USD)
Fees Earned or Paid in Cash$82,500
Total Cash Director Fees$82,500
  • Director compensation framework (2024 policy): annual retainer $60,000 for Lead Independent Director; committee member retainers $7,500 (Audit), $5,000 (Compensation), $5,000 (Nominating); committee chair retainers $15,000 (Audit), $10,000 (Compensation), $10,000 (Nominating).

Performance Compensation

Equity Award TypeGrant Value BasisVestingChange-in-Control Treatment
Annual Non-Employee Director OptionTarget aggregate value $135,000Equal quarterly over one year; fully vested at first anniversaryUnvested director options vest fully upon Change in Control if director remains in service through the date
Initial Director Option (post-merger/new appointees)Target aggregate value $270,000Equal quarterly installments; fully vested at third anniversarySame as above
2024 Reported Option Grant Value (Barchas)$134,999Per policy schedule abovePer policy above
  • Clawback oversight: Compensation Committee approves and oversees application of clawback/recoupment of incentive compensation (executive-focused; applies to incentive comp).
  • Performance metrics tied to director compensation: None disclosed; director equity awards are time-based under the Non-Employee Director Compensation Policy.

Other Directorships & Interlocks

EntityNatureDetail
Enavate Sciences L.P. (5% holder)Investor director presenceJames Boylan (CEO of Enavate) serves on IMNM’s Board; he agreed to hold board equity grants for the benefit of Enavate Sciences, L.P.
Arsenal Bridge Venture II LLC and II-B LLCAffiliated holdings of BarchasBarchas co-founded ABV II and ABV II-B; beneficial ownership includes shares held by these entities (see Ownership section).

Expertise & Qualifications

  • Life sciences investment and business expertise; leadership experience across biotech acceleration and technology incubation; prior top-tier consulting experience.
  • Legal training (J.D.), with additional academic credentials (B.A., M.A.).
  • Board leadership: Lead Independent Director with responsibilities enhancing independent oversight.

Equity Ownership

HolderShares Beneficially Owned% of OutstandingComponents
Isaac Barchas, J.D.2,612,745 3.01% 92,211 common shares; 1,471,613 via Arsenal Bridge Venture II, LLC; 942,768 via Arsenal Bridge Venture II-B LLC; 106,153 options exercisable within 60 days (Feb 1, 2025)
Options outstanding (total)129,756 Aggregate options as of Dec 31, 2024 (vested/unvested mix not separately disclosed)
  • Hedging/pledging: Company policy prohibits directors from hedging, purchasing on margin, borrowing against, or pledging company stock.
  • Section 16 compliance: Directors/officers complied in 2024 except an automatic annual director equity award filing was one day late.

Governance Assessment

  • Board effectiveness: Barchas is Lead Independent Director, chairs Nominating & Corporate Governance, and sits on Compensation—positions aligned with oversight of independence, conflicts, succession, and pay governance.
  • Independence and attendance: Affirmed independent; no director under-attendance (<75%) in 2024, indicating engagement.
  • Ownership alignment: 3.01% beneficial ownership (including affiliated entities), plus director option holdings, suggests meaningful skin-in-the-game relative to non-employee directors.
  • Compensation mix: 2024 director comp comprised $82,500 cash fees and $134,999 option grant value per policy; equity awards are time-based, not performance-contingent for directors.
  • Potential conflicts/related-party exposure: Barchas co-founded ABV II/ABV II-B (significant holdings); Enavate (5% holder) has an affiliated director (Boylan). The Board’s Related Party Transactions Policy mandates Audit Committee review/approval of covered transactions, and the Board determined no material disqualifying relationships among independent directors.
  • Risk indicators: No legal proceedings or loans disclosed related to Barchas; hedging/pledging prohibited; minor compliance note (1-day late Section 16 filing for director automatic awards) acknowledged.