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Frank Bennett

Executive Vice President, Chief Scientific Officer at IONIS PHARMACEUTICALSIONIS PHARMACEUTICALS
Executive

About Frank Bennett

Executive Vice President and Chief Scientific Officer at Ionis Pharmaceuticals; executive sponsor of the Board’s Medical and Science Committee . Recognized for 35 years of service in 2024 via the Commitment to Ionis Award, underscoring deep tenure and institutional knowledge . External leadership includes serving (not compensated) as Director and Chief Technical Officer at the n‑Lorem Foundation, a non-profit advancing RNA-targeted medicines for ultra-rare diseases . Company performance context during his recent tenure: 2024 revenue reached $705 million and year-end cash/short-term investments were $2.3 billion; executive pay programs emphasize long-term TSR-based PRSUs with tougher maximum thresholds (90th percentile) since 2023 and EVP-level cash MBO targets of 40% .

Past Roles

OrganizationRoleYearsStrategic Impact
Ionis PharmaceuticalsSVP, Research2013Senior R&D leadership; featured among executives in performance MBO evaluation (illustrates accountability to corporate objectives) .
Ionis PharmaceuticalsEVP & Chief Scientific Officer2024–2025 (current)Executive sponsor of the Medical & Science Committee, guiding key scientific and development issues .
Ionis PharmaceuticalsLong-tenure recognition2024Commitment to Ionis Award of $35,000 for 35 years of service; signals retention and institutional expertise .

External Roles

OrganizationRoleDisclosed YearsNotes
n‑Lorem FoundationDirector & Chief Technical Officer2021; 2023; 2025Non-profit role; no compensation from Ionis for this service .

Fixed Compensation

ElementPolicy/ValueNotes
EVP Target MBO %40%Applies to Executive Vice Presidents (EVPs); MBO awards are fully at-risk and formula-driven .
Company Performance Factor (Max)200%Caps company multiplier in MBO formula .
Individual Performance Factor (Max)160%Caps individual multiplier in MBO formula .
PerquisitesNoneCompany does not provide executive perquisites .
401(k) MatchUp to $17,250 (2024)100% match of first 5% of compensation; applies to all employees .

Performance Compensation

ProgramMetric/StructureTarget/ThresholdsPayout Mechanics
EVP MBO (cash, at-risk)Base Salary × Target MBO % × Company Performance Factor × Individual Performance FactorEVP Target MBO %: 40%; Company Max 200%; Individual Max 160% Awards can be zero; committee may reduce factors based on 1-, 3-, 5-year TSR; 2024 Company Performance Factor set at 125% based on objective achievements .
PRSUs (from 2023 grants onward)Relative TSR vs peer group over single 3-year periodThreshold 25th percentile = 50%; Target 50th = 100%; 60th = 125%; 75th = 150%; Maximum 90th = 200% No guaranteed vest; if TSR is negative over the period, payout capped at 100% even if percentile >50th .
Options/RSUs (time-based)Vesting schedulesOptions: 25% at year 1, then 2.08% monthly for 36 months; RSUs: 25% per year over 4 years Designed for retention and alignment; exec officers collectively had 637,243 options expire underwater over the last three years (illustrates no repricing and performance linkage) .

Equity Ownership & Alignment

TopicDetailImplication
Ownership Guidelines (Executives)2× base salary for all non-CEO executive officers Strong alignment via required holdings.
Compliance Status (as of 3/31/2025)All executive officers met guidelines except Mr. Baroldi, Ms. Devers, Mr. Jenne, and Dr. Monia (Bennett not listed among exceptions) Bennett meets ownership requirement, reinforcing alignment.
Hedging/PledgingExplicitly prohibited for all directors and employees Reduces misalignment and leverage risk.
Rule 10b5‑1 PlansRequired for executive officers and VPs; no discretionary trades outside plans (except ESPP purchases and automatic RSU/PRSU releases) Systematic selling reduces headline risk, informs trading pattern analysis.
Historical Beneficial Ownership129,882 shares reported for C. Frank Bennett as of March 31, 2014 (historical) Historical snapshot only; current individual holdings not disclosed in 2025 proxy.

Employment Terms

ProvisionNon‑Change‑in‑Control (EVP)Change‑in‑Control (EVP)Notes
Cash Severance12 months of then‑current monthly base salary 18 months of then‑current monthly base salary Double‑trigger framework applies to CIC .
BonusNot specified for EVP (CEO receives prorated target) Payment of then‑current target bonus EVP bonus paid in CIC scenario only.
Equity VestingAccelerated vesting of options/RSUs that would have vested during severance period Accelerated vesting of all outstanding options and RSUs Aligns with retention while protecting in CIC.
Health BenefitsContinued group health/dental coverage for 12 months Continued coverage for 18 months Standardized by level.
ClawbackDodd‑Frank/Rule 10D‑1 compliant; recoupment on restatements regardless of fault SameEnhances governance.
Tax Gross‑upNone; payments may be reduced for better after‑tax outcome None Shareholder‑friendly stance.
ConditionsRelease with non‑solicit & non‑disparagement; confidentiality reaffirmation Same Typical protective covenants.

Investment Implications

  • Alignment: Bennett meets executive ownership guidelines; hedging/pledging is banned, and trading must occur via 10b5‑1 plans—signals disciplined alignment and reduced discretionary selling risk .
  • Incentive design: A meaningful share of EVP pay is performance-based (MBO and PRSUs), with stringent three-year TSR hurdles and negative-TSR payout caps—this supports longer-dated execution and shareholder value creation .
  • Retention: 35-year service recognition and EVP severance/CIC protections suggest low near-term retention risk while avoiding aggressive “golden” provisions (no tax gross-ups; double-trigger only) .
  • Trading signals: Required 10b5‑1 plans imply pre-scheduled sales; monitor plan adoptions/modifications and RSU/PRSU vesting calendars for supply overhang rather than discretionary timing .
  • Governance/Shareholder sentiment: 2024 say‑on‑pay support was ~96%, indicating broad shareholder endorsement of pay practices that also apply to EVPs like Bennett .

Note: Bennett was not a named executive officer in the 2024 disclosure set; individual base salary, annual bonus paid, and current share counts were not separately disclosed in the 2025 proxy. Analysis reflects EVP‑level policies and company-wide pay structures applicable to his role, with specific historical disclosures included where available .