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David Feltquate

Chief Medical Officer at iTeos Therapeutics
Executive

About David Feltquate

David Feltquate, M.D., Ph.D. is Chief Medical Officer at iTeos Therapeutics, serving since August 2024 and age 56 as of April 24, 2025 . He holds a B.S. in biology from MIT and an M.D./Ph.D. in immunology from the University of Massachusetts Medical School . Prior roles include CMO of Palleon Pharmaceuticals (2021–2024), SVP Global Hematology Development at Novartis (2019–2021), and VP Early Clinical Development Oncology at Bristol-Myers Squibb (2016–2019) . iTeos has not disclosed TSR, revenue growth, or EBITDA growth metrics tied to his tenure; the company provides scaled EGC disclosures and has not conducted a say‑on‑pay vote while classified as an emerging growth company .

Past Roles

OrganizationRoleYearsStrategic impact
Palleon PharmaceuticalsChief Medical OfficerJun 2021 – Jul 2024Executive leadership of clinical development as CMO
Novartis AGSVP, Global Hematology DevelopmentNov 2019 – Jun 2021Led hematology development programs globally
Bristol-Myers SquibbVP, Early Clinical Development OncologySep 2016 – Oct 2019Led early-stage oncology development

External Roles

No current external directorships or board committee roles disclosed for Dr. Feltquate in the company’s proxy .

Fixed Compensation

Component2024Notes
Base salary (annual rate)$510,000Initial base per employment agreement entered July 2024
Salary paid (partial year)$214,2712024 actual paid given August 2024 start
Target bonus % of base40%2024 target; NEO bonus structure
Actual annual performance bonus (paid Mar-2025)$250,320Includes a $30,000 milestone bonus under his agreement
Additional milestone bonus eligibilityUp to $30,000 in 2024 and 20252024 milestone achieved and paid; 2025 eligibility noted

Performance Compensation

IncentiveMetricWeightingTargetActual/PayoutVesting/Timing
Annual cash bonus (2024)Company and functional objectives80% corporate / 20% individual40% of base salary$250,320 (includes $30,000 milestone component) Paid March 2025
Milestone bonus (2024)Prescribed milestones per employment agreementN/AUp to $30,000$30,000 paid for 2024 Paid in cash
Equity (time-based options)Service-based vestingN/A350,000 options at $17.46 strikeGrant date fair value $4,189,500 (2024) 25% vests on 8/1/2025; remainder monthly over 36 months; expires 8/1/2034
Equity (RSUs)Service-based vestingN/A47,000 RSUs (granted 12/6/2024)Grant date fair value $360,960 at 12/31/2024 price basis Cliff vests 12/6/2026

The company does not disclose detailed payout curves or financial performance metric weights for 2024 executive bonuses; structure described at a high level only .

Equity Ownership & Alignment

ItemDetail
Total beneficial ownership (as of 4/21/2025)47,000 shares (<1% of outstanding), consisting of RSUs as described; reported as beneficially owned in proxy table
Ownership as % of shares outstanding<1% (based on 38,273,795 shares outstanding)
Options outstanding (12/31/2024)350,000 unexercisable; strike $17.46; expiration 08/01/2034
RSUs outstanding (12/31/2024)47,000 unvested (granted 12/06/2024), cliff vest 12/06/2026
Vesting calendar (key dates)87,500 options vest 08/01/2025 (25%); remaining options vest monthly over 36 months thereafter; RSUs vest 12/06/2026
Hedging/derivativesProhibited (short sales, derivatives, hedging transactions banned for insiders)
PledgingPolicy highlights risks of margin/pledge; explicit ban covers hedging/derivatives and short sales; no explicit pledging ban stated
Ownership guidelinesNot disclosed for executives in the proxy

Employment Terms

TermCurrent economicsNotes
Employment startEmployment Agreement dated July 2024; CMO since August 2024
Non-compete/garden leaveIf company enforces non-compete post-termination, eligible to receive 50% of highest annualized base salary for up to 12 months; offsets severance/CIC payments
Severance (non‑CIC)12 months base salary continuation + employer COBRA premium reimbursement up to 12 months, subject to release
Change-in-control (double trigger)If terminated without Cause or resigns for Good Reason during CIC period: lump sum equal to Salary Continuation Benefit + 1.0x Target Bonus; COBRA reimbursement up to 12 months; full acceleration of time‑based equity upon termination and release effectiveness
Change-in-control definitionAs amended; a dissolution of the Company is not a CIC
Equity acceleration (CIC)Time-based awards accelerate on double-trigger; no single-trigger acceleration disclosed
Clawback policyCompany-wide clawback for incentive compensation (cash and equity) tied to financial goals, applicable for three completed fiscal years preceding an accounting restatement
Bonus structureTarget 40% of base; 80% company goals/20% individual for 2024

Compensation Structure Analysis

  • Mix and risk profile: 2024 pay was heavily equity-oriented at hire (options $4.19M grant-date value and RSUs $0.39M), with time-based vesting that promotes retention; cash elements included partial-year salary and a $250.3k bonus (including $30k milestone), aligning near-term incentives with defined objectives .
  • Contract enhancements amid strategic review: On May 27, 2025, CIC severance economics were enhanced to include 1.0x Target Bonus and COBRA for 12 months (double-trigger), while confirming that a dissolution is not a CIC—important given the company’s wind-down plans .
  • Hedging/derivatives prohibited: Policy bans short sales and hedging transactions, supporting alignment; no explicit pledging ban is stated (potential residual risk) .

Related Party Transactions

None disclosed specific to Dr. Feltquate; executive compensation is covered in the Executive Compensation section of the proxy -.

Risk Indicators & Red Flags

  • Strategic wind-down: The company announced an intention to wind down clinical and operational activities (5/28/2025), estimating $21.8–$24.7 million in severance/termination costs and ~$11.1 million for winding down other programs; dissolution is not a CIC, which could limit CIC-triggered benefits if a dissolution proceeds rather than a sale .
  • Tax gross-ups: No tax gross-ups disclosed for Dr. Feltquate; certain gross-ups were disclosed for the CEO/COO in 2024 .
  • Hedging/derivatives: Prohibited—reduces misalignment risk .
  • Clawback in place: Financial-goal-based incentive recoupment policy adopted, mitigating restatement risk .

Equity and Incentive Detail Tables

2024 Summary Compensation (Named Executive Officer)

YearSalary ($)Stock awards ($)Option awards ($)Non‑equity incentive ($)All other comp ($)Total ($)
2024214,271 391,040 4,189,500 250,320 9,874 5,055,005

Outstanding Equity (12/31/2024)

Grant/TypeVesting commencementExercisableUnexercisableStrikeExpiryRSUs unvestedRSU vest date
Stock options08/01/2024350,000$17.4608/01/2034
RSUs12/06/202447,00012/06/2026

Beneficial Ownership (as of 04/21/2025)

HolderShares% Outstanding
David Feltquate47,000 (underlying RSUs) <1%

Vesting Schedules and Insider Selling Pressure

  • Options: 25% of 350,000 options (87,500) vest on 08/01/2025; remaining 262,500 vest monthly over 36 months thereafter, creating continuous monthly vest releases through 2028; options carry a $17.46 strike and expire 08/01/2034 .
  • RSUs: 47,000 RSUs cliff vest on 12/06/2026, a single-date vest that can concentrate potential selling pressure around that date, subject to trading windows and policy restrictions .

Employment Contracts, Severance, and Change‑of‑Control Economics

  • Base agreement (July 2024): At‑will; base salary $510,000; target bonus 40%; Additional Bonus opportunity up to $30,000 for 2024 and 2025; initial stock option grant to purchase 350,000 shares with standard time‑based vesting .
  • May 27, 2025 amendments:
    • Non‑CIC termination: 12 months salary continuation + COBRA reimbursement up to 12 months .
    • CIC double‑trigger: Lump sum equal to Salary Continuation Benefit + 1.0x Target Bonus; COBRA reimbursement up to 12 months; acceleration of all time‑based equity on termination with effective release .
    • CIC definition excludes dissolution of the Company .

Expertise & Qualifications

  • Education: B.S. biology (MIT); M.D. and Ph.D. in immunology (UMass Medical School) .
  • Domain experience: Oncology/hematology development leadership across large biopharma (Novartis, BMS) and biotech CMO roles (Palleon) .

Investment Implications

  • Alignment and retention: Dr. Feltquate’s equity is primarily time-based (350,000 options at $17.46 and 47,000 RSUs), creating strong service-based retention incentives but limited explicit performance linkage; hedging is prohibited, supporting alignment .
  • Near-term vest milestones: A significant option vest (87,500) on 08/01/2025 and steady monthly vesting thereafter may create periodic supply overhangs, subject to window restrictions and policy .
  • Transaction dynamics: CIC benefits are double-trigger and explicitly do not cover a dissolution, which is notable given the company’s intent to wind down operations; a sale of assets or entity-level transaction would determine whether CIC terms are triggered, affecting realized executive payouts and potential overhang on shareholder proceeds .
  • Cash costs of wind‑down: Expected severance and program wind‑down costs ($21.8–$24.7 million and ~$11.1 million, respectively) frame the magnitude of cash outflows ahead, with executive arrangements amended to enhance CIC coverage—important for assessing liquidation vs. sale pathways and timing .