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Terrance McGuire

Director at IVVD
Board

About Terrance McGuire

Terrance McGuire (age 69) is an independent director of Invivyd (IVVD) serving since October 2020. He is co‑founder and a general partner of Polaris Partners, and currently serves on the boards of Seer, Inc. and Tectonic Therapeutic, Inc., with extensive prior board experience across biotech and technology. He holds a B.S. in physics and economics (Hobart College), an M.S. in engineering (Dartmouth’s Thayer School), and an M.B.A. (Harvard Business School) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Alector, Inc.DirectorNot disclosedNot disclosed
Acceleron Pharma, Inc.DirectorNot disclosedNot disclosed
Akamai Technologies, Inc.DirectorNot disclosedNot disclosed
Cubist, Inc.DirectorNot disclosedNot disclosed
Cyclerion Therapeutics, Inc.DirectorNot disclosedNot disclosed
Ironwood Pharmaceuticals, Inc.DirectorNot disclosedNot disclosed
Pulmatrix, Inc.DirectorNot disclosedNot disclosed

External Roles

OrganizationRoleTenureNotes
Polaris PartnersCo‑founder; General PartnerNot disclosedVenture capital leadership
Seer, Inc.DirectorNot disclosedCurrent public company directorship
Tectonic Therapeutic, Inc.DirectorNot disclosedCurrent public company directorship
Adimab, LLCDirectorNot disclosedPrivate company; material partner and 18.1% shareholder in IVVD
Whitehead Institute for Biomedical Research (MIT)Board memberNot disclosedNon‑profit governance
Arthur Rock Center for Entrepreneurship (HBS)Board memberNot disclosedAcademic governance
Thayer School of Engineering (Dartmouth)Board of AdvisorsNot disclosedAcademic governance
Brigham & Women's HospitalScientific Advisory BoardNot disclosedHospital advisory role

Board Governance

  • Independence: The Board affirmatively determined all current directors and nominees, including McGuire, are independent under Nasdaq rules; Audit and Compensation committees meet enhanced independence standards .
  • Committee assignments: Audit Committee members are Kevin F. McLaughlin (chair), Tamsin Berry, and Marc Elia (per committee report signatures), indicating McGuire is not on Audit . Compensation Committee members are Srishti Gupta, M.D. and Christine Lindenboom (with Kevin F. McLaughlin anticipated post‑meeting), indicating McGuire is not on Compensation . Nominating & Corporate Governance committee membership for McGuire is not specifically disclosed in the proxy’s text rendering .
  • Board leadership: Independent Board Chairperson is Marc Elia, separate from management .
  • Attendance: In 2024 the Board held 9 meetings; each director attended at least 75% of Board and applicable committee meetings. Five directors attended the 2024 Annual Meeting .
  • Committee activity (2024): Audit (5 meetings), Compensation (10), Nominating & Corporate Governance (7) .

Fixed Compensation

ComponentPolicy/Amount2024 McGuire Actual
Annual Board Cash Retainer$40,000 per non‑employee director $44,000 fees earned in cash
Committee Chair Cash RetainersAudit $15,000; Compensation $10,000; Nominating $8,000 Not disclosed for McGuire
Committee Member Cash RetainersAudit $7,500; Compensation $5,000; Nominating $4,000 Not disclosed for McGuire
Meeting FeesNot disclosedNot disclosed
Executive Committee Retainer$5,000/month (May 2024–Jan 2025) for designated members; Elia waived Not applicable to McGuire (not listed)

Performance Compensation

Equity Component2024 Value/TermsVesting/Other Terms
Option awards (grant‑date fair value)$65,270 (2024 director option award) Director annual option: 50,000 shares granted at each annual meeting; vests on earlier of first anniversary or next annual meeting
Initial director option (for new directors)100,000 shares at first appointment (policy, amended Mar 2023) 1/3 on first anniversary, then 1/36 monthly to full vest at 3 years
Exercise priceClosing price on grant date; 10‑year term Post‑termination exercise: 12 months unless for cause
Change‑in‑controlDirector options subject to accelerated vesting upon change in control Accelerates per policy

Other Directorships & Interlocks

EntityRelationship to IVVDMcGuire’s RolePotential Interlock/Conflict Notes
Adimab, LLC18.1% beneficial owner; strategic discovery/licensing partnerBoard memberMultiple material agreements (Assignment & License, Collaboration, Platform Transfer, Sequencing) and cash/milestone/royalty payments; reviewed under Related Person Transactions policy
Polaris‑affiliated funds5.7%+ holdings via Polaris entitiesGP/interest holder in GPsShared voting/dispositive power; McGuire has roles in GPs; options included in his total

Expertise & Qualifications

  • Venture capital leadership focused on biotech; prior and current public company board service across therapeutics and tech .
  • Education: B.S. physics/economics (Hobart), M.S. engineering (Dartmouth Thayer), M.B.A. (Harvard) .

Equity Ownership

MetricAmountNotes
Total beneficial ownership7,008,590 shares (5.8% of outstanding) Includes Polaris‑affiliated holdings; shared voting/dispositive powers as described
Options outstanding210,593 options (as of Dec 31, 2024) Included in director option rollforward; specific vest status not disclosed
Ownership guidelinesNot disclosed
Shares pledged as collateralNot disclosed
Hedging policyCompany prohibits hedging by directors and employees

Governance Assessment

  • Alignment and influence: Significant beneficial ownership (5.8%) via Polaris‑affiliated entities signals financial alignment, though shared control structures may complicate direct accountability .
  • Independence and attendance: Board determined independence; attendance threshold met (≥75%), supporting baseline effectiveness .
  • Committee positioning: Not on Audit or Compensation committees, reducing direct influence over financial reporting and pay design; committee memberships otherwise not specified in text rendering .
  • Director pay structure: Modest cash retainer with equity options consistent with market practice; change‑in‑control acceleration exists, which can be investor‑unfriendly if not coupled with strong performance rationale .
  • Related‑party exposure:
    • Adimab interlock is material. IVVD made milestone and royalty payments and maintains multiple agreements; Adimab is a major shareholder. Audit Committee oversees related‑party transactions under formal policy, mitigating but not eliminating conflict risk .
    • Polaris holdings create potential perceptions of influence over strategic direction; disclosures detail governance of GPs and McGuire’s roles .
  • Controls and policies: Insider trading and hedging prohibitions and a clawback policy exist, supporting governance hygiene; company is an emerging growth company and thus exempt from say‑on‑pay advisory votes at this time .

RED FLAG: Board interlock with Adimab (supplier/shareholder) given scale of payments and strategic agreements; requires sustained Audit Committee oversight under the Related Person Transactions Policy to protect minority shareholders .

Signal: Meaningful ownership and long biotech board tenure can enhance strategic guidance and investor confidence if conflicts are actively managed and committee governance remains robust .

Appendix: Director Compensation Detail (2024)

ItemAmount
Fees earned (cash)$44,000
Option awards (grant‑date fair value)$65,270
Total$109,270
Options held (as of 12/31/2024)210,593

Appendix: Board & Committee Activity (2024)

BodyMeetings
Board of Directors9
Audit Committee5
Compensation Committee10
Nominating & Corporate Governance Committee7

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