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Judith Shizuru

Director at Jasper Therapeutics
Board

About Judith Shizuru

Judith Shizuru, M.D., Ph.D., age 69, is a Class II director whose current term expires at the 2026 annual meeting; she has served on Jasper’s boards since 2018 (pre-merger and post-merger continuity) and is the company’s scientific co‑founder . She is a Professor of Medicine (Blood and Marrow Transplantation) and Pediatrics (Stem Cell Transplantation) at Stanford, with a B.A. from Bennington College and M.D./Ph.D. from Stanford; she trained in internal medicine at UCSF and hematology at Stanford and has over 160 publications focused on immunology and transplant conditioning including translational anti‑CD117 antibody work .

Past Roles

OrganizationRoleTenureCommittees/Impact
Jasper (Pre‑Merger Board)DirectorMar 2018 – Sep 2021Scientific co‑founder; continuity into public listing
Jasper Scientific Advisory BoardChairDec 2019 – Sep 2021Led translational strategy; anti‑CD117 conditioning progressed to clinic

External Roles

OrganizationRoleTenureCommittees/Impact
Stanford UniversityProfessor of Medicine (BMT) and Pediatrics (Stem Cell Transplantation)OngoingMember: BMT‑CT faculty, Immunology Program, Stanford Cancer Institute, Institute for Stem Cell Biology & Regenerative Medicine

Board Governance

  • Board classification: Class II; current term expires 2026; board size eight directors with staggered terms .
  • Independence: Board determined Dr. Shizuru is not independent due to paid consulting services to the company .
  • Committee assignments: Member, Research & Development Committee; R&D Committee members are Dr. Brun (Chair), Dr. Shizuru, and Mr. von Emster; held four meetings in FY 2024 .
  • Other committees and chairs: Audit (members Nolet, von Emster, Kapoor; Chair Nolet; Nolet designated audit committee financial expert) ; Compensation (members von Emster, Nolet, Brun; Chair Nolet; four meetings and six written consents in FY 2024) ; Nominating & Corporate Governance (members von Emster, Lucas, Kapoor; Chair von Emster; two meetings and three written consents in FY 2024) .
  • Board meeting cadence and attendance: Six board meetings in FY 2024; each director attended at least 75% of board and committee meetings during their service period; independent directors generally meet in executive session after each regular board meeting .

Fixed Compensation

MetricFY 2023FY 2024
Fees Earned or Paid in Cash (USD)$46,300 $46,300
Other Compensation (Consulting) (USD)$250,000 $250,000
Total Cash (Fees + Consulting) (USD)$296,300 $296,300

Non‑Employee Director Cash Retainers (policy in effect during 2024):

RoleChairperson Annual Cash Retainer (USD)Each Other Member Annual Cash Retainer (USD)
Board of Directors$70,000 $40,000
Audit Committee$15,000 $7,500
Compensation Committee$10,000 $5,000
Nominating & Corporate Governance Committee$8,000 $4,000
Research & Development Committee$11,300 $6,300

Note: Dr. Shizuru’s 2024 cash fees of $46,300 align with the standard $40,000 board retainer plus $6,300 for R&D committee membership .

Performance Compensation

MetricFY 2023FY 2024
Option Awards – Grant Date Fair Value (USD)$61,410 $161,489
Aggregate Options Outstanding (shares, as of year‑end)27,120 34,620

Director Equity Award Policy Details:

Policy ElementBefore Apr 19, 2024Effective Apr 19, 2024
Initial Option Grant (new directors)9,400 shares; 25% vest at 1‑year; 1/48 monthly thereafter 15,000 shares; 25% vest at 1‑year; 1/48 monthly thereafter
Annual Option Grant4,700 shares; vest in full at 1‑year 7,500 shares; vest in full at 1‑year

No director PSUs/RSUs or performance metric‑based director awards disclosed; director equity is solely in the form of stock options with time‑based vesting .

Other Directorships & Interlocks

  • No other public company boards disclosed for Dr. Shizuru; profile emphasizes academic leadership and scientific expertise .
  • Compensation Committee interlocks: None; no cross‑appointments involving Jasper executives on external compensation committees .

Expertise & Qualifications

  • Immunology, antibody and cellular therapies, transplant conditioning agents; co‑founded Jasper and led translational science of anti‑CD117 conditioning from lab to clinic; 160+ publications .
  • Board qualifications cited by the company: deep domain expertise and knowledge of Jasper’s technology and product candidates .

Equity Ownership

Ownership Metric (as of Apr 30, 2025)Amount
Total Beneficial Ownership (shares)150,521
Ownership as % of Shares Outstanding1.0% (out of 15,022,122 shares)
Directly Held Shares115,901
Options Exercisable within 60 days34,620

Option Holdings Reference:

ItemShares
Aggregate options outstanding as of Dec 31, 202434,620

Policies:

  • Hedging and pledging of company stock are prohibited for directors, employees, and consultants under the Insider Trading Policy .

Insider Trades (recent):

DateTypeSharesPrice (USD)Source
Sep 22, 2025Open‑market purchase41,000$2.43
Jul 3, 2025 (filed)Annual director option grant7,500N/A

Governance Assessment

  • Independence and conflict risk: Board has formally determined Dr. Shizuru is not independent due to a longstanding consulting relationship ($20,833 per month; $250,000/year since Dec 16, 2019), creating potential conflict when advising on R&D or strategic decisions; this is a notable governance red flag .
  • Attendance and engagement: Board met six times in 2024; each director met at least the 75% attendance threshold; R&D Committee (where she serves) met four times, indicating active committee oversight .
  • Compensation mix and alignment: 2024 director pay comprised $46,300 cash fees, $161,489 option awards, and $250,000 consulting cash; the largest component was consulting, which reduces at‑risk alignment versus equity‑based compensation .
  • Equity alignment: 1.0% beneficial ownership (150,521 shares including 34,620 near‑term exercisable options) and recent open‑market share purchase signal some alignment; hedging/pledging prohibitions strengthen alignment .
  • Committee structure and oversight: Independent chairs lead key committees (Audit—Nolet; Compensation—Nolet; Nominating—von Emster), with executive sessions after regular board meetings; Shizuru’s role is confined to the R&D Committee, which fits her scientific expertise .

Related Party Transactions

  • Consulting Agreement: Entered Dec 16, 2019; services provided in exchange for $20,833 per month ($250,000 per year), disclosed as related party; the consulting fee also appears as “Other Compensation” in the director compensation table .

Compensation Structure Analysis

  • Shift in director equity value: Option grant fair value rose from $61,410 in 2023 to $161,489 in 2024, consistent with policy change increasing annual option awards from 4,700 to 7,500 shares and initial option awards from 9,400 to 15,000 shares effective April 19, 2024 .
  • Guaranteed vs at‑risk pay: The $250,000 consulting cash represents a guaranteed, non‑board service compensation component that can dilute pay‑for‑performance signals for a director role .
  • No evidence of repricing, tax gross‑ups, or director performance‑metric awards for 2023–2024 .

Director Compensation (Detail)

YearFees Earned (USD)Option Awards (USD)Other Compensation (USD)Total (USD)
2023$46,300 $61,410 $250,000 $357,710
2024$46,300 $161,489 $250,000 $457,789

Option award values represent grant date fair values under ASC 718 as disclosed .

RED FLAGS

  • Not independent due to paid consulting—ongoing related party arrangement; board explicitly classifies her as non‑independent .
  • Significant non‑board cash compensation ($250,000/year) alongside board service, which can present perceived conflicts in R&D oversight given committee membership .

Notes

  • Board meeting attendance specifics for Dr. Shizuru beyond “≥75%” were not individually disclosed for 2024; company reported aggregate compliance across directors .
  • Director stock ownership guidelines were not disclosed for non‑employee directors; hedging/pledging prohibitions apply to directors, employees, and consultants .