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Alison Silva

President and Chief Business Officer at JUPITER NEUROSCIENCES
Executive
Board

About Alison Silva

Alison D. Silva is President and Chief Business Officer of Jupiter Neurosciences (JUNS) and a director since 2018. She is 47 years old, with a B.A. in Biology from Clark University (2001) and a graduate degree from the University of Massachusetts Medical Center (2002), and previously served as CEO of Cotinga Pharmaceuticals; she also held senior operating roles at Synlogic Therapeutics and other biotech companies . She has served as President and CBO since September 1, 2021, bringing extensive leadership across biotech commercialization and operations . The proxy does not disclose TSR or operating performance metrics for her tenure; executive compensation philosophy emphasizes Board discretion and has not included formal performance-based stock option grants to date .

Past Roles

OrganizationRoleYearsStrategic Impact
Cotinga Pharmaceuticals (formerly Critical Outcome Technologies)Chief Executive Officer2016–2021Led turnaround and governance; continued board service since 2015
The Microbiome Company → Synlogic TherapeuticsEVP & Chief Operating Officer2013–2016Co-founded platform; scaled operations in synthetic biology therapeutics
Marina BiotechCo-founder & VP, DevelopmentNot disclosedEarly-stage development leadership in RNA/biotech
The Orphan GroupCo-founder & DirectorNot disclosedFocus on rare disease strategy and advocacy
Cequent PharmaceuticalsDirector, Drug DevelopmentNot disclosedPipeline development responsibilities
SLA PharmaChief Operating OfficerNot disclosedOperational management in specialty pharma

External Roles

OrganizationRoleYearsNotes
Cotinga PharmaceuticalsDirectorSince 2015Ongoing board service
EMA WellnessManagement ConsultantNot disclosedAdvisory role
The Orphan GroupManagement ConsultantNot disclosedAdvisory role

Fixed Compensation

Metric ($)FY 2023FY 2024
Base Salary96,250
Bonus
All Other Compensation35,000 42,294
Total Compensation545,083 138,544
  • 2023 salary was deferred and effective October 1, 2023 reduced to $60,000; no interest accrued on deferred amounts .

Performance Compensation

Award TypeFY 2023 ($)FY 2024 ($)
Stock Awards (RSUs)146,602
Option Awards363,481
  • Executive Compensation Philosophy: Bonuses are at Board discretion based on business objectives and revenue; the Board has not granted performance-based stock options to date, and reserves the right to do so in the future .
  • 12/18/2023 amendment: Cash bonuses previously promised were forgiven, options related to the forgiveness vested fully on the effective date, and RSUs tied to that program were replaced to vest upon IPO or change of control (aggregate program-wide amounts) .

Equity Ownership & Alignment

Ownership & Awards (as of dates noted)Value/AmountDetails
Beneficial Ownership (as of Oct 24, 2025)983,648 shares; 2.8% of classIncludes exercisable derivatives within 60 days of 10/24/2025; based on 34,426,355 shares outstanding
Options Exercisable (as of Dec 31, 2024)0None exercisable at year-end
Options Unexercisable (as of Dec 31, 2024)870,871Exercise price $1.20; expirations 2028–2033
Unvested Stock Awards (as of Dec 31, 2024)$110,227 market valueRSUs not vested at year-end
Ownership GuidelinesNot disclosedNo stock ownership guideline disclosure in proxy
Pledging/HedgingNot disclosed; Insider Trading Policy and blackout periods applyCompany has an Insider Trading Policy; Plan contemplates blackout periods and other restrictions

Employment Terms

TermProvisionSource
Role startPresident & CBO since 9/1/2021
Agreement termThree years with automatic one-year renewals unless 30-day prior notice
Employment statusAt-will; either party may terminate at any time subject to agreement provisions
Fringe benefits & expensesExecutives entitled to fringe benefits consistent with Company practices; reimbursement for reasonable business expenses
ClawbackAwards subject to Company clawback policy and applicable laws
Change-of-controlRSUs issued in the 9/29/2023 forgiveness program replaced to vest upon IPO or change of control (aggregate program)
2023 compensation changeSalary deferred; reduced to $60,000 effective 10/1/2023

Board Governance

  • Service history and status
    • Director since 2018; current age 47 .
    • Non-independent director (employee) alongside CEO and CSO; majority of board is independent .
  • Committee roles
    • Audit Committee comprises Weis (Chair), Brady, Hemmerly; Silva is not listed on standing committees .
  • Director compensation
    • Employees serving as directors (CEO, CSO, Silva) received no additional director compensation in 2024 .
    • Non-employee director policy post-IPO: $30,000 annual board retainer plus committee fees; initial director option grant 67,500 options at $1.33 vesting ratably over 36 months (policy context) .
  • Governance structure
    • CEO and Chairman roles combined (Christer Rosén), with periodic review and executive sessions of independent directors to mitigate risks .

Compensation Structure Analysis

  • Year-over-year shift from equity-heavy (2023 RSUs/options totaling $510,083) to cash-light 2024 (salary $96,250; no new equity awards), reflecting capital conservation and reduced guaranteed pay .
  • Discretionary, non-formula bonuses; absence of disclosed performance metrics and no performance-based stock options to date—limited pay-for-performance transparency .
  • 12/18/2023 modification accelerated vesting of options tied to forgiveness and converted RSUs to IPO/change-of-control vesting—potential red flag for award repricing/modification and event-driven supply .

Risk Indicators & Red Flags

  • Non-independent dual role (President/CBO + Director) may constrain board independence, though overall board maintains independent majority .
  • Award vesting modifications (full vesting upon amendment; RSUs vest on IPO/CiC) increase event-driven selling pressure risk .
  • Combined CEO/Chair structure (not Silva’s role, but overall governance context) elevates concentration risk; mitigated by executive sessions of independent directors .
  • Insider trading controls present; blackout and plan restrictions noted, but no explicit hedging/pledging prohibitions disclosed .

Performance Compensation – Award Detail and Vesting

Metric/FeatureWeightingTargetActualPayoutVesting
Executive cash incentiveNot disclosedNot disclosedNot disclosedBoard discretionNot disclosed
2023 RSUsNot disclosedNot disclosedNot disclosed$146,602 grant-date FVProgram RSUs (forgiveness) replaced to vest on IPO/CiC
2023 OptionsNot disclosedNot disclosedNot disclosed$363,481 grant-date FVOptions tied to forgiveness fully vested upon amendment date

Director Compensation (Context)

ComponentAmount
Board Annual Retainer (non-employee)$30,000
Audit Committee Member$5,000; Chair $10,000
Compensation Committee Member$5,000; Chair $10,000
Nominating & Governance Member$4,000; Chair $7,500
Initial Director Option Grant67,500 options @ $1.33; vest over 36 months
Employee Directors (incl. Silva)No additional director pay (2024)

Equity Award Inventory (As of Dec 31, 2024)

InstrumentExercisable (#)Unexercisable (#)Exercise PriceExpirationUnvested RSUs (MV $)
Stock Options0 870,871 $1.20 2028–2033 110,227

Employment & Contracts – Additional Terms

ClauseTerm
Auto-renewalAnnual extensions unless 30-day notice pre-expiration
At-willTermination by either party at any time, subject to agreement terms
ClawbackAwards subject to Company clawback policy and applicable laws
Expense policyReimbursement per Company practices for necessary business expenses

Investment Implications

  • Alignment: Silva’s ~2.8% beneficial ownership indicates meaningful alignment; however, significant unvested options/RSUs and IPO/CiC vesting features create potential event-driven selling pressure as awards become liquid .
  • Pay-for-performance visibility: The absence of disclosed performance metrics and reliance on discretionary bonuses reduce transparency, limiting ability to tie pay outcomes to value creation; watch for future introduction of PSUs or metric-linked incentives .
  • Governance: Non-independent executive-director role and combined CEO/Chair structure elevate governance risk; independent majority and executive sessions partially mitigate, but continued monitoring of committee independence and board processes is warranted .
  • Award modifications: The 12/18/2023 vesting accelerations and RSU conversions may foreshadow further equity program changes; track subsequent proxy updates for any repricings or broadened acceleration provisions that could dilute shareholders .