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Shalom Z. Hirschman

Director at Klotho Neurosciences
Board

About Shalom Z. Hirschman

Independent director at Klotho Neurosciences, age 88. Academic physician-scientist with leadership at NIH and Mount Sinai; later biotech CEO and senior academic roles at Touro College/University System. Currently serves on KLTO’s board, which is a single class of directors elected annually until the next stockholder meeting .

Past Roles

OrganizationRoleTenureCommittees/Impact
Mount Sinai School of Medicine & HospitalDirector, Division of Infectious Diseases; Professor of Medicine; Vice-Chair, Department of Medicinec. three decadesDiscovery of HBV DNA polymerase, HBV replication, characterized viral DNA; first description of AIDS as an immunologic disease
National Institutes of Health (NIH)Molecular biology/virology researcherNot disclosedFoundational research experience
Advanced Viral Research Corp.CEO, President, Chief Scientific OfficerNot disclosedBuilt FDA-approved manufacturing facility; advanced peptide drug into IND clinical trials
Touro College / Touro University SystemSenior VP roles; Co-founder; Board memberBoard service > three decadesNegotiated purchase of New York Medical College for Touro

External Roles

OrganizationRoleCurrent/PastNotes
Sunrise Securities CorporationConsultantPast 5 yearsAlso consulted to educational institutions, biotech companies and investment funds

Board Governance

  • Committee assignments: Member, Compensation Committee; Member and Chair, Nominating & Corporate Governance Committee .
  • Chair roles: Chair of the Nominating & Corporate Governance Committee .
  • Independence: Compensation Committee and Nominating & Corporate Governance Committee members, including Dr. Hirschman, satisfy Nasdaq/SEC independence requirements .
  • Director terms: Single class of directors; each serves until the next annual meeting or until a successor is elected .
  • Governance policies: Code of Ethics adopted for all directors/officers/employees ; Insider Trading Policy on file ; Clawback policy on file ; Indemnification and D&O insurance authorized by charter .

Fixed Compensation

Component2024 AmountNotes
Annual cash retainer$120,000Fees earned/paid in cash to Shalom Z. Hirschman

No meeting fees, committee chair fees, or equity grants are disclosed for Dr. Hirschman in the 2024 director compensation table .

Performance Compensation

Performance metric tied to director payStatusNotes
Any performance-based metrics (TSR, revenue, ESG)Not disclosedNo performance-linked director compensation metrics disclosed for Dr. Hirschman in 2024

Other Directorships & Interlocks

CompanyTypeRoleInterlock/Conflict Considerations
Advanced Viral Research Corp.Biotech (prior)CEO/President/Chief Scientific Officer (prior)Historical operating role; no current public board disclosed
Touro College / Touro University SystemHigher educationSenior VP; Co-founder; long-time Board member (prior)Educational governance; no vendor/customer interlocks disclosed with KLTO

No current public company directorships are disclosed for Dr. Hirschman .

Expertise & Qualifications

  • Clinical/scientific credentials: NIH researcher; Director of Infectious Diseases at Mount Sinai; extensive published contributions including HBV DNA polymerase discovery and AIDS immunologic characterization .
  • Biotech operating experience: Led AVRC as CEO/President, built FDA-compliant manufacturing, advanced IND trials .
  • Academic governance: Co-founder and long-serving board member at Touro, with senior administrative leadership and major acquisition execution (NYMC) .

Equity Ownership

HolderShares Beneficially Owned% of OutstandingNotes
Shalom Z. Hirschman488,7241.7%As of March 26, 2025; footnotes do not indicate options for Dr. Hirschman, unlike other directors
All directors and executive officers (7 individuals)7,684,18226.7%Concentration among insiders
Pledging statusNot disclosed/none indicatedCompany notes no arrangements including pledges that may result in change in control

Governance Assessment

  • Board effectiveness: Dr. Hirschman brings deep scientific and clinical expertise and chairs Nominating & Corporate Governance, supporting board refreshment and policy oversight .
  • Independence and alignment: Independent status on key committees and meaningful equity stake (1.7%) support shareholder alignment .
  • Compensation structure: Cash-only director pay disclosed for 2024; absence of equity grants to Dr. Hirschman reduces long-term alignment relative to equity-heavy structures common in biotech boards .
  • Controls and oversight risk indicators:
    • Material weakness in internal controls and ineffective disclosure controls reported by management, increasing oversight demands on Audit and Governance committees .
    • Going-concern uncertainty and low cash ($63,741 at year-end 2024) heighten capital-raising and strategic risk, requiring active board engagement .
    • Nasdaq listing deficiencies noted in 2024–2025 (market value and bid-price notices), with reverse split authority sought; board compliance plans will be a focal area for governance .
  • Related-party/Conflict review: Company disclosed several related-party notes to management; no specific related-party transactions involving Dr. Hirschman were disclosed . His consulting to Sunrise Securities should be monitored for any potential engagements with KLTO to avoid conflicts .
  • Shareholder rights and policies: Code of Ethics, Insider Trading Policy, and Clawback Policy are in place; as an emerging growth company, KLTO is exempt from say-on-pay and certain compensation disclosures, limiting shareholder feedback channels on pay practices .

RED FLAGS

  • Material weaknesses in ICFR and ineffective disclosure controls .
  • Going-concern doubt and minimal cash balance at FY2024 end .
  • Nasdaq compliance issues (market value and bid price), reverse split authorization .
  • High insider/5% holder concentration (62.7% combined), potential governance entrenchment risk .