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Jean-Jacques Bienaimé

Lead Independent Director at Keros Therapeutics
Board

About Jean‑Jacques Bienaimé

Jean‑Jacques Bienaimé, age 71, joined the Keros Therapeutics Board in June 2024 and has served as Lead Independent Director since July 2024 . He previously served as CEO of BioMarin Pharmaceutical (2005–Dec 2023) and Chairman (2015–Dec 2023), and earlier was Chairman/CEO/President of Genencor (2002–2005) and Sangstat (1998–2002), with senior roles at Rhône‑Poulenc Rorer and earlier work at Genentech . He currently serves on the boards of Incyte Corporation and Immunome, Inc., and two private biotechnology companies; he holds an MBA from Wharton and a degree in economics from École Supérieure de Commerce de Paris .

Past Roles

OrganizationRoleTenureCommittees/Impact
BioMarin Pharmaceutical Inc.Chief Executive Officer; ChairmanCEO: May 2005–Dec 2023; Chair: Jun 2015–Dec 2023 Led growth of rare‑disease portfolio (biotech operator experience)
Genencor, Inc.Chairman, CEO, PresidentNov 2002–Apr 2005 Industrial bioproducts and targeted cancer biotherapeutics focus
Sangstat Medical CorporationChairman, CEO, President (President in 1998; CEO in 1999)1998–late 2002 Immunology‑focused biotechnology
Rhône‑Poulenc Rorer (now Sanofi‑Aventis)Senior Vice President, Worldwide Marketing & Business Development1992–1998 Global commercial leadership
Genentech, Inc.Executive (product launch contributor)Early career (date not specified) Involved in launch of t‑PA

External Roles

OrganizationRoleStart (if disclosed)Committees/Impact
Incyte CorporationDirectorNot disclosed in KROS proxy
Immunome, Inc.DirectorNot disclosed in KROS proxy
Two private biotech companiesDirectorNot disclosed

Board Governance

  • Lead Independent Director: Appointed July 2024; responsibilities include presiding over meetings without the Chair, serving as liaison between independent directors and CEO/Chair, and consulting on agendas/materials and scheduling .
  • Committee assignments (2024): Nominating & Corporate Governance (member); not on Audit or Compensation in 2024; Nominating & Corporate Governance met 6 times, Audit 4, Compensation 8 .
  • Independence: Board determined Bienaimé is independent under Nasdaq rules (eight of nine directors independent) .
  • Attendance/engagement: Board met nine times in 2024; each Board member attended ≥75% of Board/committee meetings for the period served (Bienaimé joined June 2024) .
  • Board leadership: KROS combines CEO and Chair roles; appointment of Bienaimé as Lead Independent Director provides counterbalance and facilitates independent oversight .

Fixed Compensation

Non‑Employee Director Cash Compensation PolicyAnnual Cash Retainer ($)
Annual director retainer 40,000
Additional retainer – Chair 30,000
Additional retainer – Lead Independent Director (effective Jul 1, 2024) 25,000
Audit Committee Chair / member 15,000 / 7,500
Compensation Committee Chair / member 12,000 / 6,000
Nominating & Corporate Governance Chair / member 10,000 / 5,000
2024 Non‑Employee Director Compensation (Actual)Fees Earned or Paid in Cash ($)Option Awards – Grant Date FV ($)Total ($)
Jean‑Jacques Bienaimé (joined June 2024) 38,709614,224652,933

Notes: Cash retainers are paid quarterly and prorated for partial service; Lead Independent Director retainer effective July 1, 2024 . 2020 equity plan caps director total value (cash + equity) at $500,000 per annual period, or $700,000 in the year first appointed/elected—Bienaimé’s first year total equity grant FV falls within the $700,000 cap .

Performance Compensation

Non‑Employee Director Equity ProgramTerms
Instrument Stock options (10‑year term)
Initial award on joining Board Option to purchase 20,000 shares; vests in equal quarterly installments over 3 years
Annual award (each annual meeting) Option to purchase 10,000 shares; vests quarterly over 12 months; fully vested by next annual meeting
Change in control Options vest in full upon a change in control
Post‑termination exercise (non‑death/disability/cause) 12 months after service ends
Bienaimé – Option Positioning as of 12/31/2024Value / Shares
Aggregate grant date FV of 2024 option awards ($) 614,224
Shares underlying outstanding options 17,600

Clawback and equity grant controls: Keros maintains a Dodd‑Frank‑compliant recoupment policy (Oct 5, 2023) and has established equity award grant timing safeguards to avoid MNPI timing issues .

Other Directorships & Interlocks

  • Current public company boards: Incyte Corporation; Immunome, Inc. .
  • Independence and conflicts: The Board found no material or disqualifying relationships for independent directors, including Bienaimé .
  • Related‑party transactions: Keros’ related‑party policy governs review/approval; no related‑party transactions involving Bienaimé are disclosed in the proxy .

Expertise & Qualifications

  • Executive leadership: Former CEO/Chairman of BioMarin; prior CEO roles at Genencor and Sangstat; senior commercial roles at Rhône‑Poulenc Rorer; product launch experience at Genentech .
  • Industry expertise: Deep biotech/pharma operating and board experience .
  • Education: MBA (Wharton); Economics degree (École Supérieure de Commerce de Paris) .

Equity Ownership

Beneficial Ownership (as of April 11, 2025)Shares / %
Common shares owned 200
Options exercisable within 60 days 5,866
Total beneficial ownership (SEC definition) 6,066; “*” less than 1% of outstanding
Shares outstanding basis 40,611,414 shares outstanding (for % calc)
Options outstanding (12/31/2024) 17,600
Hedging/pledgingCompany policy prohibits hedging, short sales, options, margin and pledging by directors

Governance Assessment

  • Strengths

    • Lead Independent Director role provides robust counterweight to combined CEO/Chair structure; responsibilities explicitly defined to enhance independent oversight .
    • Confirmed independence and absence of disqualifying relationships; board maintains regular executive sessions without management .
    • Strong engagement indicators: Board met 9 times in 2024; directors (including Bienaimé for his period of service) met or exceeded the 75% attendance threshold .
    • Director equity is option‑based with long vesting and full acceleration on change‑in‑control; first‑year grant value within plan cap; aligns director incentives with shareholder value creation .
    • Hedging/pledging prohibited, supporting alignment and risk controls; clawback policy in place .
  • Watch‑items

    • Combined CEO/Chair structure generally concentrates power; mitigated by a clearly empowered Lead Independent Director (Bienaimé) .
    • Multiple external public boards (Incyte; Immunome) increase time commitments; Board nonetheless determined Bienaimé is independent and qualified .
  • Conflicts/Related‑party

    • No related‑party transactions disclosed involving Bienaimé; Board and committee independence affirmed .
  • Compensation mix and transparency

    • 2024 director pay was predominantly equity (options), consistent with Keros’ policy to align director interests; Bienaimé’s higher first‑year equity value reflects onboarding grant mechanics and remains within the first‑year cap .