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Ian Clark

Chairperson of the Board at Kyverna Therapeutics
Board

About Ian Clark

Ian Clark (age 64) is an independent director and the Chairperson of the Board at Kyverna Therapeutics (KYTX). He has served on the KYTX board since 2021 (Class II; term ends at the 2026 annual meeting) and brings 35+ years in biopharma, including as former CEO of Genentech; he holds a B.Sc. in Biological Sciences and an Honorary Doctorate of Science from the University of Southampton (UK) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Genentech, Inc.Chief Executive Officer and Director~2009–Dec 2016 (CEO 7 years)Brought 11 new medicines to market across RA, IPF, oncology
Roche GroupEVP, Head of Global Product StrategyApr 2009–Dec 2009Global product strategy leadership
Genentech (prior roles)EVP Commercial Ops; SVP, GM BioOncology2003–2009Led commercial/BioOncology growth
Novartis, Sanofi, Ivax, SearleVarious senior roles (US, UK, Canada, E. Europe, France)Prior 23 years pre-2003International commercial leadership

External Roles

OrganizationRoleTypeNotes
Takeda Pharmaceutical Company Limited (TAK)DirectorPublicCurrent board service
Corvus Pharmaceuticals (CRVS)DirectorPublicCurrent board service
Guardant Health (GH)DirectorPublicCurrent board service
Olema Pharmaceuticals (OLMA)DirectorPublicCurrent board service
GoodRx Holdings (GDRX)DirectorPublicCurrent board service
KKR & Co. Inc.AdvisorPrivate equityCurrent advisor

Board Governance

  • Structure and independence:
    • Board leadership separated: Warner Biddle is CEO; Ian Clark serves as independent Chairperson, a structure the board deems appropriate to balance oversight and management focus .
    • Independence: Board determined Ian Clark and six other directors are independent under Nasdaq rules; independent directors meet in regular executive sessions .
  • Committees and roles:
    • Nominating & Corporate Governance Committee: Chair (members: Ian Clark (Chair), Christi Shaw, Beth Seidenberg, M.D.) .
    • Not a member of Audit, Compensation, or Science & Technology Committees per board composition table .
  • Board/committee activity and attendance:
    • 2024 meetings: Board (10), Audit (6), Compensation (5), Nominating (2), Science & Tech (4); each director attended at least 75% of applicable meetings; no annual meeting held in 2024 .
  • Tenure: Director since 2021; Class II term ends at the 2026 annual meeting .

Fixed Compensation

Component2024 Program DetailIan Clark 2024 Actual
Annual board retainer (cash)$40,000 per non-employee director (paid quarterly) Included in total below
Independent Chair retainer (cash)+$35,000 per year Included in total below
Committee chair – Nominating & Corp Gov+$10,000 per year (chair); members +$5,000 Included in total below
Other committee retainersAudit: Chair $20k; member $10k. Comp: Chair $15k; member $7.5k. Sci & Tech: Chair $15k; member $7.5k N/A (not a member)
2024 fees earned (cash)Paid quarterly; directors could elect to convert retainers to RSUs $88,750 cash

Performance Compensation

ElementGrant Value/TypeVesting2024 Grants to Ian ClarkNotes
Initial equity (pre-3/25/25 design)$350,000 option for new directors after 2/12/24 1/36 monthly over 3 years NoneApplies to new appointees in period
Annual equity (pre-3/25/25 design)$175,000 option at each annual meeting (if ≥4 months service) Full on earlier of 1 year or next annual meeting NoneNo annual meeting held in 2024
Restated program (effective 3/25/25)Initial: $262,500 option + $87,500 RSUs Option monthly over 3 yrs; RSUs 1/3 per year over 3 yrs N/A in 2024Structure for new appointees after 3/25/25
Annual (from 2025 meeting onward)Choice of $131,250 option or $43,750 RSUs each annual meeting Full vest by 1 year/next annual meeting N/A in 2024From 2025 annual meeting
Change-in-control accelerationAll outstanding director equity vests in full upon change-in-control ImmediateN/AApplies to all non-employee directors

No performance metrics apply to director equity; grants are time-based; directors may elect to convert cash retainers into fully vested RSUs and can defer settlement .

Other Directorships & Interlocks

CompanyRelationship to KYTXPotential Interlock/Conflict
Takeda, Corvus, Guardant, Olema, GoodRxUnrelated to KYTX per proxy disclosuresNo disclosed related-party transactions involving Ian Clark; no supplier/customer ties disclosed

Expertise & Qualifications

  • Former Genentech CEO (7 years) and global biopharma executive; led launches across oncology, RA, IPF; deep commercial and global operating experience .
  • Board leadership: Independent Chair at KYTX; chairs Nominating & Corporate Governance; extensive public company board experience (Takeda, Guardant, GoodRx, etc.) .
  • Education: B.Sc. Biological Sciences; Honorary D.Sc., University of Southampton (UK) .

Equity Ownership

ItemDetail
Beneficial ownership (as of 3/15/2025)285,951 shares beneficially owned, all via options exercisable within 60 days; no common shares reported directly held
Options outstanding (12/31/2024)364,398 shares underlying options
Hedging/pledgingCompany prohibits hedging, short sales, derivative transactions, margin purchases, and pledging by directors; no pledging permitted (policy-wide)
Ownership guidelinesNot disclosed in proxy for directors; directors can elect to receive RSUs for retainers (fully vested at grant; deferrable)

Governance Assessment

  • Strengths
    • Independent Board Chair with extensive operating experience; independent status affirmed by Board .
    • Chairs the Nominating & Corporate Governance Committee; committee independence confirmed .
    • Attendance: Board indicates all directors met ≥75% threshold in 2024; robust meeting cadence across committees .
    • Shareholder-aligned practices: hedging/pledging prohibited; director equity accelerates on change-in-control; option/RSU mix introduced in 2025, allowing equity deferral .
    • Compensation advisor (Aon Radford) assessed independent by the Compensation Committee, reducing consultant conflict risk .
  • Potential Risk Indicators
    • Board service load: simultaneously serves on at least five other public company boards (Takeda, Corvus, Guardant, Olema, GoodRx), which some governance frameworks consider “overboarding” risk for a public-company chair .
    • Securities litigation: KYTX and certain directors, including Ian Clark, named in a December 2024 shareholder class action regarding the IPO registration statement; outcome unknown as of proxy filing .

Related-Party & Conflicts Check

  • Related-party transactions disclosed involve other directors’ affiliated funds (Vida Ventures, Westlake BioPartners, Northpond) and certain executives; no Ian Clark-specific related-party transactions disclosed .
  • Insider trading and clawback frameworks are in place company-wide (clawback policy effective 2/7/2024; insider trading policy prohibits hedging/pledging) .

Director Compensation (Detail)

YearFees Earned (Cash)Option Awards (Grant Date FV)OtherTotal
2024$88,750 $0 $88,750
  • Program mechanics:
    • Cash retainers per role (Board and committees) as outlined in Fixed Compensation above (paid quarterly; pro-rated in 2024; retainer-to-RSU election available) .
    • No 2024 annual option grants due to no annual meeting; new 2025 program adds RSUs and mixed grant choices .

Other Notable Governance Policies

  • Emerging Growth Company (EGC): reduced compensation disclosures and no advisory say-on-pay vote while EGC status persists .
  • Clawback: SEC- and Nasdaq-compliant policy to recover incentive-based pay tied to financial reporting measures in the event of restatements (3-year lookback) .

RED FLAGS

  • Overboarding risk: simultaneous service on five other public company boards may constrain time/attention, especially given KYTX is transitioning to late-stage development and commercialization .
  • Securities litigation naming director: inclusion in class action over IPO disclosures (filed Dec 2024) can be an overhang for investor confidence until resolved .

Overall implication: Governance structures (independent chair, strong committee independence, risk/ethics policies) are solid, but investors should monitor workload/overboarding optics and the status of the securities litigation for potential reputational or time-allocation impacts .