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Warner Biddle

Warner Biddle

Chief Executive Officer at Kyverna Therapeutics
CEO
Executive
Board

About Warner Biddle

Warner Biddle, 58, has served as Chief Executive Officer (CEO) and Director of Kyverna Therapeutics (KYTX) since September 2024 and holds a Bachelor’s Degree in Commerce (Honors) from the University of Saskatchewan . In 2024 (the company’s first year as a public company), Kyverna reported no product revenue and a net loss of $127.5M (vs. $60.4M in 2023) as R&D scaled into late-stage development for lead CAR-T KYV-101; cash, cash equivalents and marketable securities were $286.0M at year-end 2024, providing at least 12 months of runway from the 10-K issuance date . As an emerging growth company (EGC), Kyverna has not held a say‑on‑pay vote; executive bonuses are based on corporate and individual goals (metrics not itemized) .

Past Roles

OrganizationRoleYearsStrategic Impact
Kyverna TherapeuticsChief Executive Officer and DirectorSep 2024–presentLeads pivot to late‑stage development/commercialization of KYV‑101 in autoimmune CAR‑T .
Kite Pharma (Gilead)SVP, Global Head of CommercialAug 2020–Sep 2024Shaped global commercial strategy in cell therapy; leadership across corporate development peers on board .
GenentechVP & Franchise Head, Breast/Gyn & Skin CancersJan 2018–Aug 2020Led cross‑functional strategy and key launches; drove portfolio growth .
GenentechVP, Sales & Marketing, OphthalmologyNov 2013–Dec 2015Commercial leadership in ophthalmology franchise .
Novartis; GlaxoSmithKlineVarious global leadership rolesPrior years (Europe/Canada)Multi‑therapeutic leadership across geographies .

External Roles

  • No current public company directorships or external committee roles for Mr. Biddle are disclosed in the proxy .

Fixed Compensation

Component2024 Terms/Amounts
Base Salary$625,000 annualized (prorated for 2024 start in Sep 2024) .
Sign‑On Bonus$650,000 paid Oct 2024; repayable if terminated for Cause or resignation without Good Reason before Sep 16, 2025 .
RelocationUp to $150,000 reimbursement .
Legal Fee Reimbursement$25,000 related to offer letter .

Performance Compensation

IncentiveMetric(s)TargetActual (2024)Payout MechanicsVesting/Terms
Annual Bonus (2024)Corporate and individual goals (metrics not itemized) 60% of base salary $375,000 Determined Jan 2025 by Board/Comp Committee N/A
Long‑Term Equity (Inducement Option)Service‑based stock option (Inducement Plan)2,579,259 options; exercise price $6.89 Grant‑date fair value $13,760,605 Time‑based vesting (no performance conditions) 25% vests Sep 16, 2025; remainder monthly (1/48th) thereafter; expires 9/16/2034

Equity Ownership & Alignment

ItemDetail
Beneficial Ownership (as of Mar 15, 2025)0 shares reported beneficially owned by Warner Biddle .
Options Outstanding (12/31/2024)2,579,259 options unexercisable; exercise price $6.89; expiry 9/16/2034 .
Vesting Overhang / Supply Consideration25% tranche (≈644,815 options) scheduled to vest on Sep 16, 2025, with monthly vesting thereafter, subject to continued service .
Hedging/PledgingCompany policy prohibits hedging and pledging by covered persons, including NEOs .
ClawbackSEC/Nasdaq‑compliant clawback policy for incentive‑based compensation tied to financial reporting measures .
Ownership GuidelinesNot disclosed in proxy (no executive ownership multiple referenced) .

Employment Terms

TermSummary
Employment BasisAt‑will .
Target BonusUp to 60% of base salary (not prorated for 2024) .
Severance (Non‑CIC)If terminated without Cause or resigns for Good Reason: (a) 18 months base salary; (b) lump‑sum target bonus; (c) up to 18 months COBRA reimbursement; (d) 18 months vesting acceleration on unvested service‑based equity (performance awards, if any, at target) — payable on/after day 60 post‑separation subject to release .
Severance (CIC Double Trigger)If separation occurs within 12 months following a Change in Control: 100% acceleration of all unvested equity (performance at target) in addition to cash severance terms above .
Sign‑On ClawbackFull sign‑on ($650k) repayable if terminated for Cause or voluntary resignation without Good Reason before Sep 16, 2025 .
Restrictive CovenantsConfidentiality and inventions assignment; non‑compete during employment; non‑solicit during employment and one year post‑employment .

Board Governance and Board Service

  • Service: Class III director; term expires at the 2027 annual meeting; director since 2024 .
  • Independence: Board determined 7 of 8 directors are independent; the CEO (Biddle) is the sole non‑independent director .
  • Leadership structure: CEO and Chair roles are separated (Ian Clark serves as Chair), which the Board believes optimizes oversight .
  • Committees: Audit, Compensation, Nominating & Corporate Governance, Science & Technology are fully independent; no committee roles disclosed for Biddle as an executive director .
  • Attendance: In 2024, the Board met 10 times; each director attended ≥75% of Board/committee meetings to which they were appointed during the year .
  • Director Compensation: Employee directors receive no additional pay for board service; non‑employee director program summarized in proxy .

Additional Context: Company Performance and Risk

  • Financial trajectory: 2024 total operating expenses rose to $142.6M (from $62.4M in 2023), driven by R&D scaling for KYV‑101; net loss widened to $127.5M (from $60.4M) .
  • Liquidity: $286.0M in cash and marketable securities at 12/31/2024; management expects this funds operations for at least 12 months from 10‑K issuance .
  • Litigation: A shareholder class action was filed Dec 2024 naming certain current and former officers and directors (as listed in the proxy); the matter is disclosed in Corporate Governance, Legal Proceedings .

Compensation Structure Analysis

  • Heavy front‑loaded equity aligned to long‑term value creation: 2.58M inducement options with a one‑year cliff and monthly vest schedule support retention and alignment with equity upside; not performance‑based .
  • 2024 cash mix included a large sign‑on ($650k) and a full‑year target bonus not prorated, signaling priority on immediate retention and onboarding (note: sign‑on subject to clawback if early departure) .
  • Bonus metrics not itemized (EGC scaled disclosure), limiting visibility into pay‑for‑performance calibration beyond Board/Comp Committee discretion .
  • Robust severance and CIC provisions (18‑month cash and partial time‑based equity acceleration; full acceleration in CIC) reduce CEO turnover risk but may raise payout leverage in downside scenarios .

Director Compensation (for completeness)

ElementProgram Summary
Cash Retainers (Non‑Employee Directors)$40k annual; Chair +$35k; Committee chairs/members additional retainers (e.g., Audit Chair $20k) .
EquityInitial and annual grants under 2024 Plan; restated in Mar 2025 to blend Options and RSUs; full vest on change in control .
Employee DirectorsNo additional compensation for board service .

Investment Implications

  • Alignment and retention: The one‑year cliff on 2.58M options (25% vests on Sep 16, 2025) creates a near‑term retention tether; expect the first significant vesting tranche to occur in Q3 2025, with potential mechanical sell‑to‑cover activity depending on trading plans and tax needs .
  • Pay‑for‑performance visibility: Lack of disclosed bonus metric weightings and thresholds (EGC scaled disclosure) limits external assessment of incentive rigor; monitoring future proxy detail (as EGC status phases out) will be important .
  • Downside protection: CEO severance/CIC economics (18‑month cash; partial/full acceleration) mitigate leadership transition risk during pivotal development/commercialization milestones but increase potential costs in adverse outcomes .
  • Trading signals: Company policy prohibits hedging/pledging; Biddle reported zero beneficial ownership as of Mar 15, 2025, with all equity as unvested options—focus monitoring on 10b5‑1 adoptions, Form 4 activity around and after the Sep 2025 cliff, and any incremental inducement or refresh grants .
  • Balance sheet and execution: With $286.0M of liquidity and no product revenue, execution on KYV‑101 registrational path and timelines (SPS/MG Phase 2 and Phase 1/2 readouts in 2H25) is the key value driver; compensation design emphasizes retention through this catalyst window .