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Graham Cooper

Chairman at Kezar Life SciencesKezar Life Sciences
Board

About Graham Cooper

Independent Chairman of the Board at Kezar Life Sciences (KZR), age 55, serving as director since 2017 and elevated to Chairman in May 2022. He is a seasoned biotech finance executive and audit committee financial expert, currently CFO of Tavo Biotherapeutics; prior roles include CFO/COO at Assembly Biosciences, CFO at Receptos and Geron, with earlier healthcare banking experience at Deutsche Bank and a CPA earned at Deloitte; education includes a BA in Economics (UC Berkeley) and MBA (Stanford) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Assembly Biosciences, Inc.Chief Financial Officer & Chief Operating OfficerMar 2018 – Apr 2019Operational and financial leadership
Receptos, Inc.Chief Financial OfficerFeb 2013 – Aug 2015Took company through growth phase
Geron CorporationCFO & EVP Finance & Business DevelopmentJan 2012 – Dec 2012Corporate development and finance
Orexigen Therapeutics, Inc.Chief Financial OfficerPrior to 2012Finance leadership
Deutsche Bank SecuritiesDirector, Health Care Investment BankingPrior to DeloitteTransaction advisory in biotech
Deloitte & Touche LLPAccountant (CPA)Early careerEarned CPA credential

External Roles

OrganizationRoleTenureNotes
Tavo Biotherapeutics, Inc.Chief Financial OfficerCurrentOperating CFO role
Beam Therapeutics, Inc. (public)DirectorSince Oct 2019Current public company directorship
Celladon Corporation (public)DirectorPriorFormer public board
Unity Biotechnology, Inc. (public)DirectorPriorFormer public board
Applied Molecular Transport, Inc. (public)DirectorPriorFormer public board

Board Governance

  • Independence: Board affirmatively determined Cooper is independent under Nasdaq rules; KZR maintains an independent Board Chair model, with Cooper serving as independent Chair .
  • Committee assignments (FY2024): Audit Committee Chair (financial expert), Compensation Committee member; not on Nominating/Governance .
  • Board/committee activity and attendance: Board met 10 times in FY2024; each incumbent director attended at least 75% of Board and committee meetings; independent directors held four executive sessions without management .
CommitteeRoleMeetings (FY2024)
AuditChair; Financial Expert4
CompensationMember5
Nominating & Corporate GovernanceNot a member1
BoardIndependent Chair10 (Board meetings)

Fixed Compensation

ComponentAmount (USD)Notes
Board Chair annual cash retainer$70,000Non-employee Chair
Audit Committee Chair retainer$15,000Additional annual
Compensation Committee member retainer$5,000Additional annual
Fees earned (2024 actual)$90,000Reflects Chair + Audit Chair + Comp member

Performance Compensation

KZR compensates directors primarily with stock options; no PSUs/RSUs or cash performance bonuses disclosed for non-employee directors. Hedging/pledging of company stock is prohibited under the insider trading policy, which supports alignment and risk control .

Equity ElementGrant SizeVestingExercise Price Basis2024 Option Awards ExpensedOutstanding Options (12/31/2024)
Initial director option grant10,000 sharesMonthly over 3 years (service-based)Fair market value on grantN/A (policy) N/A
Annual director option grant5,000 shares12 months cliff (service-based)Fair market value on grant$24,375 22,709

Other Directorships & Interlocks

CompanyMarket StatusRolePotential Interlock/Notes
Beam Therapeutics, Inc.PublicDirectorCooper sits on Beam’s board; another KZR director (Wallace) previously served as Beam executive (Chief Business Officer), not a director; monitor information flow
Tavo Biotherapeutics, Inc.Private (implied)CFOConcurrent executive role may impact time commitments; no related-party transactions disclosed with KZR

Expertise & Qualifications

  • Financial expert: Designated audit committee financial expert; deep CFO experience across biotech and investment banking .
  • Capital markets and M&A: Deutsche Bank healthcare investment banking background; multiple CFO roles through funding cycles .
  • Governance leadership: Independent Board Chair structure enhances oversight; leads executive sessions .
  • Credentials: CPA (Deloitte), BA Economics (UC Berkeley), MBA (Stanford) .

Equity Ownership

HolderShares Beneficially Owned% of Shares OutstandingComposition / Notes
Graham Cooper17,709<1%Shares issuable upon exercise of stock options exercisable within 60 days of April 1, 2025; no direct common stock listed; pledging/hedging prohibited by policy
Shares Outstanding (reference)7,305,800Shares outstanding at record date for 2025 proxy

Governance Assessment

  • Positives:
    • Independent Chair model with Cooper leading Board oversight; separation from CEO strengthens accountability .
    • Audit Chair and financial expert designation; oversight of financial reporting and risk management processes .
    • Attendance at least 75% for all incumbents; independent directors held four executive sessions (FY2024), indicating active oversight .
    • Prohibition on hedging/pledging and robust governance policies (Code of Conduct, Corporate Governance Guidelines) .
  • Concerns/RED FLAGS:
    • 2024 Say-on-Pay approval of 42% indicates shareholder dissatisfaction with compensation practices; Board acknowledged feedback that the July 2023 option repricing (without shareholder approval) may misalign pay and performance—future repricings to consider shareholder concerns. This is a governance signal requiring continued monitoring .
    • Low personal ownership: Beneficial ownership is entirely option-based and <1%, which may suggest limited “skin in the game” versus cash retainer and service-based options .
    • Multiple external commitments: Concurrent CFO role at Tavo Biotherapeutics and board service at Beam could present time constraints; no KZR-related party transactions disclosed, but monitor for interlock/information flow risks .
  • Compensation oversight:
    • Cooper sits on Compensation Committee alongside an independent consultant (Semler Brossy) engagement and peer benchmarking, which supports process rigor; however, the 2023 option repricing controversy underscores the need for enhanced shareholder engagement and restraint on award modifications .

Overall, Cooper’s independent Chairmanship and audit expertise are strengths for board effectiveness; the 2023 option repricing and weak 2024 say-on-pay outcome are governance headwinds requiring visible remediation and improved pay-for-performance alignment .