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Brian Markison

Brian Markison

Chief Executive Officer at Lantheus HoldingsLantheus Holdings
CEO
Executive
Board

About Brian Markison

Brian A. Markison is Chief Executive Officer and a Class III director at Lantheus, age 65, with more than 40 years of operational, marketing, commercial development and sales experience in pharmaceuticals; he holds a B.S. from Iona College . He joined the LNTH board in September 2012, served as Chair from January 2013 to March 1, 2024, became Executive Chairman on January 23, 2024, and CEO on March 1, 2024 . Company performance in 2024 included net revenue of $1,533.9 million and net income of $312.4 million; LNTH’s total shareholder return (value of $100 initial investment) reached $436.18 in 2024, reflecting strong pay-for-performance alignment used in LNTH’s incentive programs .

Metric202220232024
Net Revenue ($USD Millions)$935.1 $1,296.4 $1,533.9
Net Income ($USD Millions)$28.1 $326.7 $312.4
LNTH TSR (Value of $100)$248.46 $302.29 $436.18

Past Roles

OrganizationRoleYears (disclosed)Strategic Impact
King PharmaceuticalsCOO (March 2004), later President & CEO; Chairman (2007)Joined Mar 2004; Chairman from 2007 Led company through leadership transition and growth in multiple therapeutic areas
Fougera PharmaceuticalsPresident & CEO; DirectorPrior to sale to Sandoz (Novartis generics) Led specialty dermatology company to sale to Sandoz
Bristol-Myers SquibbPresident roles (Oncology, Virology, OTN; Neuroscience, Infectious Disease, Dermatology); SVP Operational ExcellencePrior to King tenure Senior leadership across therapeutic franchises and operations

External Roles

OrganizationRoleYearsNotes
RVL Pharmaceuticals plcDirectorCurrent Former Executive Chair at predecessor Vertical/Trigen
College of New JerseyDirectorCurrent Governance role
Cosette PharmaceuticalsFormer DirectorPriorBoard service concluded
ImmunomedicsFormer DirectorPriorBoard service concluded
Alere, Inc.Former DirectorPriorBoard service concluded

Fixed Compensation

Component2024 ValueNotes
Base Salary$950,000 (as of 12/31/2024) Established Jan 23, 2024 (Executive Chairman), maintained upon CEO appointment
Salary Paid (SCT)$855,000 Reflects actual 2024 paid amount per SCT
Target Bonus %100% of base salary CEO target bonus design
Actual Bonus (NEIP)$1,189,020 Derived from 119.2% corporate factor and 105% individual factor
All Other Compensation$250,525 Includes benefits/perquisites; LNTH adopted executive financial advisory and physical programs in 2024

Performance Compensation

2024 Executive Bonus Plan

MetricWeightingThresholdTargetActualPayout (% of Target)Weighted Payout
Net Revenue40%$1,319M $1,465M $1,533M 123% 49.4%
Bonus EPS30%$5.02 $5.91 $6.17 115% 34.4%
Strategic Objectives30%100% 100% 118% 118% 35.4%
Corporate Performance Factor119.2%
CEO Individual Performance Factor105%

CEO achievements cited included successful CEO transition, M&A prioritization (e.g., Life Molecular RM2 global rights, Meilleur Technologies acquisition), driving PYLARIFY and DEFINITY performance, and reinforcing a performance-based culture .

2024 Long-Term Incentives (granted March 1, 2024)

Award TypeMetricGrantDesign & Vesting
PSUsrTSR vs S&P 400 Health Care65,748 target PSUs; max 131,496 3-year performance period (1/1/2024–12/31/2026); payout: 200% at ≥75th percentile, 100% at 50th, 50% at 25th, 0% below; cliff vest at 3 years
RSUsTime-based65,748 RSUs Vest in equal installments over three years, service-based

PSU payout calibration remains 100% rTSR-based; beginning with 2025 grants, payout is capped at target if absolute TSR is negative over the period .

Equity Ownership & Alignment

ItemDetail
Beneficial Ownership68,434 shares; includes 7,866 options exercisable within 60 days; excludes 109,580 unvested RSUs/PSUs/options
Shares Outstanding Basis68,480,308 shares (record date Mar 3, 2025)
Ownership % of Outstanding~0.10% (68,434 / 68,480,308)
Outstanding Equity at 12/31/2024RSUs: 65,748 ($5,881,816 MV); PSUs (max basis): 131,496 ($11,763,632 MV)
Options Outstanding4,068 @ $64.20 (exp. 5/6/2032); 3,798 @ $99.38 (exp. 5/11/2033)
2024 Exercises/VestingOptions exercised: 32,768 shares, value realized $2,712,707; RSUs/PSUs vested: 2,012 shares, value $156,695
Ownership GuidelinesCEO must hold shares equal to 6x base salary; other execs 2x; 50% of after-tax shares from vest/exercise retained until compliance; 5-year compliance window
Hedging/PledgingProhibited for directors/employees; margin accounts and pledging disallowed; no exceptions

Employment Terms

TermKey Provision
Start and RoleExecutive Chairman effective January 23, 2024; CEO effective March 1, 2024
Severance (Non-COC)1× annual base salary + prorated target bonus + Company COBRA portion up to 12 months; paid over 12 months
Severance (Double-Trigger COC)2× annual base salary + 2× full-year target bonus + Company COBRA portion for 24 months; full vesting of unvested equity (PSUs at target); paid lump sum
Death/DisabilityProrated target annual bonus (elapsed portion), lump sum
280G/4999Modified cut-back; reduction to avoid excise tax unless after-tax amount is greater without reduction
Retirement Feature (Equity)At retirement ≥ age 55 with ≥10 years service (and required notices): vested options exercisable up to 3 years; unvested PSUs continue on original terms prorated; unvested RSUs forfeited; Markison meets qualifications as of 12/31/2024

Board Governance

  • Board service: Director since September 2012; Chair from January 2013 to March 1, 2024; currently CEO and director, Class III term expiring at 2027 annual meeting .
  • Committee roles: LNTH committees (Audit; Talent & Compensation; Nominating & Corporate Governance; Science & Technology) are 100% independent; Markison, as CEO, does not serve on committees .
  • Independence and leadership: Board has nine independent directors out of eleven; Chair (Mary Anne Heino) is not independent; Lead Independent Director (Julie McHugh) appointed with robust duties to balance non-independent Chair and CEO dual roles .
  • Meetings and attendance: In 2024, Board held 9 meetings; committees held 4–8 meetings; each director attended ≥75% of meetings; executive sessions occur at end of most meetings and at least twice per year under guidelines .
  • Director compensation policy: Employee directors (CEO) receive no additional director compensation .

Compensation Structure Analysis

  • Mix and design: CEO target compensation emphasizes variable pay; 2024 LTI mix for CEO was 50% PSUs and 50% RSUs per employment agreement, converging to standard mix in 2025; PSUs are 100% rTSR-based, supporting shareholder alignment .
  • Market positioning: Talent & Compensation Committee targets 50th percentile of market for target compensation, with discretion based on performance and role-specific factors .
  • Pay versus performance: 2024 Corporate Performance Factor 119.2% and CEO IPF 105% drove bonus payout; say-on-pay approval in 2024 was ~97%, indicating strong shareholder support .
  • Governance safeguards: Clawback policy compliant with Nasdaq/SEC for restatements; prohibition on hedging/pledging; ownership guidelines increased to 6× salary for CEO in Oct 2024 .

Equity Awards Detail (2024 Grants and Outstanding)

CategoryQuantityKey Dates/Terms
2024 PSUs granted65,748 target; max 131,496 Performance period 1/1/2024–12/31/2026; cliff vest at 3 years; rTSR vs S&P 400 Health Care
2024 RSUs granted65,748 Vest one-third annually over 3 years
Outstanding options (12/31/2024)4,068 @ $64.20 (exp. 5/6/2032); 3,798 @ $99.38 (exp. 5/11/2033) Prior director grants; one-year vest for director awards; otherwise standard three-year vesting applies

Say-on-Pay & Peer Group

  • Say-on-Pay: 2024 approval ~97% .
  • Peer group: 2024 peer group refreshed; LNTH positioned at $1,366M revenue and $8,568M market cap vs peer medians ($1,565M revenue; $8,323M market cap) .
  • Target percentile: Committee targets 50th percentile for target comp opportunities, with adjustments based on performance and contribution .

Investment Implications

  • Strong alignment and performance leverage: CEO incentives hinge on Net Revenue, Bonus EPS, strategic objectives, and multi-year rTSR PSUs; 2024 corporate factor at 119.2% and rTSR-only PSU design create direct linkage to shareholder returns .
  • Retention and selling pressure: Large unvested PSUs/RSUs (RSUs 65,748; PSUs max 131,496) and 6× salary ownership guideline with 50% retention rule reduce near-term selling and enhance alignment; hedging/pledging strictly prohibited, limiting adverse trading signals .
  • Change-of-control economics: Double-trigger COC provides 2× salary + 2× target bonus and full equity acceleration at target for performance awards—material economics that could influence deal negotiation incentives; 280G modified cut-back mitigates excise tax risk .
  • Retirement eligibility dynamics: Retirement feature allows continued PSU vesting on prorated basis while forfeiting unvested RSUs—implies sustained exposure to long-term performance even upon retirement; Markison meets retirement qualifications as of year-end 2024 .
  • Operational execution risk and track record: 2024 delivered $1.5339B revenue and strong TSR; CEO’s 2024 IPF highlights M&A execution and brand leadership in PYLARIFY/DEFINITY, but clinical catalysts (e.g., SPLASH interim analysis below expectations) underscore pipeline execution risks that feed into strategic bonus objectives .

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