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Paula HJ Cholmondeley

Director at Lexeo Therapeutics
Board

About Paula HJ Cholmondeley

Independent director (Class III) since November 2021; age 77; current term expires at the 2026 annual meeting . She is CEO of Sorrel Group (strategy and corporate governance consulting) since January 2004, NACD part‑time faculty since June 2008, a NACD Certified Director and in the NACD Directorship 100; former CFO of Independence Blue Cross and formerly a Certified Public Accountant; B.S. in Accounting (Howard University) and M.S. from the Wharton School of the University of Pennsylvania . LXEO’s board has determined she is independent under Nasdaq rules; she serves as Audit Committee chair and is designated an “audit committee financial expert” .

Past Roles

OrganizationRoleTenureCommittees/Impact
Sorrel GroupChief Executive OfficerJan 2004–presentStrategy and corporate governance advisor
National Association of Corporate Directors (NACD)Part‑time faculty; NACD Certified Director; Directorship 100Jun 2008–presentBoard governance expertise and director education
Independence Blue Cross LLCChief Financial OfficerFormerFinancial leadership; former CPA
Industrial products companiesExecutive rolesOperational and financial management experience

External Roles

OrganizationRoleTenureCommittees/Impact
Bank OZK (public, regional bank)DirectorSince May 2016
Terex Corporation (public manufacturing)DirectorSince 2004
Nationwide Mutual FundsDirector2002–2022

Board Governance

  • Committee assignments: Audit Committee (Chair; financial expert); Compensation Committee (Member) .
  • Independence: Board affirmed independence for seven of eight directors, including Ms. Cholmondeley, per Nasdaq and SEC criteria (Rule 10A‑3, Rule 10C‑1) .
  • Attendance: Board met 9 times in FY2024; each director attended at least 75% of board and applicable committee meetings; Audit Committee met 6 times; Compensation Committee met 4 times; Nominating & Corporate Governance Committee met 4 times .
  • Board structure: Independent chair (Dr. Altschuler) separate from CEO; majority independent board composition .

Fixed Compensation

ComponentFY 2024
Fees Paid or Earned in Cash ($)$61,000
Total Cash (context)Base Director Fee $40,000; Audit Committee Chair $15,000; Compensation Committee Member $6,000 (annual policy amounts)

Director Cash Retainer Policy (annual):

PositionAnnual Cash Retainer
Base Director Fee$40,000
Chair of the Audit Committee$15,000
Compensation Committee Member$6,000

Performance Compensation

CategoryFY 2024 / Policy Details
Option Awards (grant‑date fair value)$217,314
Initial Director Option Grant36,000 options; vests over 3 years in equal annual installments; exercise price at fair market value; accelerates on change‑in‑control
Annual Director Option Grant18,000 options each annual meeting (pro‑rated if mid‑year); vests by next annual meeting or one year; accelerates on change‑in‑control
Equity Awards Outstanding (12/31/2024)3,582 stock awards; 62,184 options outstanding

Performance Metrics Applied to Director Compensation:

Metric TypeDisclosure
Financial/TSR/ESG metricsNone disclosed; non‑employee director awards are time‑based options under the Director Compensation Policy

Other Directorships & Interlocks

CompanyRelationship to LXEOPotential Interlock/Conflict Notes
Bank OZKExternal board (financial services)No LXEO‑disclosed related‑party transactions with Ms. Cholmondeley; sector unrelated to biotech operations
Terex CorporationExternal board (industrial manufacturing)No LXEO‑disclosed related‑party transactions with Ms. Cholmondeley; sector unrelated to biotech operations
Nationwide Mutual FundsFormer external board (2002–2022)No LXEO‑disclosed related‑party transactions with Ms. Cholmondeley

Expertise & Qualifications

  • Audit committee financial expert; financial sophistication per Nasdaq and SEC definitions; former CFO and CPA strengthen oversight of reporting, controls and audit independence .
  • Governance practitioner and educator (NACD faculty; Certified Director; Directorship 100), signaling board process rigor and governance literacy .
  • Broad executive experience across industrial products and financial services, adding operating and risk management perspective .

Equity Ownership

Beneficial Ownership (as of April 15, 2025):

MetricValue
Shares Beneficially Owned (Number)74,811
Percentage of Shares Outstanding<1% of 33,196,997
Shares Outstanding Base33,196,997

Ownership Breakdown:

ComponentShares
Common shares owned30,627 (includes 1,628 restricted shares subject to company repurchase right >60 days)
Options exercisable within 60 days44,184 (includes 24,853 unvested shares eligible via early option exercise)
Stock awards outstanding (12/31/2024)3,582
Options outstanding (12/31/2024)62,184

Policies affecting alignment:

  • Policy prohibiting hedging or pledging by directors and employees (no short sales, options, hedges, margin accounts, or speculative transactions) .

Governance Assessment

  • Strengths:

    • Independent Audit Chair and designated “audit committee financial expert,” with six audit meetings in FY2024, indicating active oversight of reporting, auditor independence and risk, including cybersecurity oversight .
    • Board affirmed independence; majority independent board; separation of chair and CEO; attendance ≥75% across board and committees, supporting engagement .
    • Director compensation emphasizes equity options with clear vesting and market‑based exercise price; absence of hedging/pledging enhances alignment .
    • Compensation Committee uses an independent consultant (Alpine Rewards) and met four times, supporting rigor in pay oversight and peer benchmarking .
  • Watch items / RED FLAGS:

    • Change‑in‑control accelerates all director option awards (single‑trigger acceleration), which can be viewed as shareholder‑unfriendly in some governance frameworks if not performance‑conditioned. RED FLAG .
    • No explicit director stock ownership guidelines disclosed in the proxy (corporate governance guidelines and director compensation policy are disclosed but do not specify director ownership minimums), limiting formal “skin‑in‑the‑game” policy signaling .
    • Multiple external public boards could present time‑commitment risk, although FY2024 attendance thresholds were met; continued monitoring warranted .
  • Conflicts and related‑party exposure:

    • Proxy discloses related‑party transactions (e.g., milestone payment to CMO tied to a pre‑acquisition earn‑out; investor rights with certain holders), but none involve Ms. Cholmondeley; LXEO maintains a written policy for related person transactions overseen by the Audit Committee .
  • Compliance signals:

    • No Section 16(a) filing delinquencies for FY2024 among directors and officers, supporting controls around insider trading compliance .

Appendix: Committee Composition and Meetings (FY2024)

CommitteeMembershipRoleFY2024 Meetings
AuditPaula HJ Cholmondeley; Mette Kirstine Agger; Reinaldo DiazChair: Paula; all independent; Paula is financial expert6
CompensationReinaldo Diaz; Steven Altschuler, M.D.; Paula HJ CholmondeleyChair: Diaz; all independent4
Nominating & Corporate GovernanceMette Kirstine Agger; Tim Van Hauwermeiren; Brenda Cooperstone, M.D.Chair: Agger; all independent4
Science & Technology (formed Apr 22, 2024)Brenda Cooperstone, M.D. (Chair); Steven Altschuler, M.D.; Rajiv Patni, M.D.; Ronald G. Crystal, M.D.Oversight of R&D and IP— (charter disclosed)

Citations: Board composition and director details; Biography for Paula HJ Cholmondeley; Director independence determination; Board leadership, committees and attendance; Audit Committee composition, charter and meetings; Compensation Committee composition, consultant independence and meetings; Nominating & Corporate Governance and Science & Technology committees; Corporate governance guidelines and Director Compensation Policy; Director compensation table and outstanding equity awards; Policy prohibiting hedging or pledging; Beneficial ownership table; Footnote detailing Paula’s beneficial ownership components; Section 16(a) compliance; Related person transactions and investors’ rights agreement; Audit Committee report and financial expert designation.