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Samuel Barker

Director at LEXICON PHARMACEUTICALSLEXICON PHARMACEUTICALS
Board

About Samuel L. Barker, Ph.D.

Independent Class II director of Lexicon Pharmaceuticals since March 2000; former Chairman of the Board (2005–2012). Age 82. Career includes senior operating roles at Bristol‑Myers Squibb (EVP Worldwide Franchise Management & Strategy; President, U.S. Pharmaceuticals; President, Intercontinental Commercial Operations) and co‑founder/CEO of Clearview Projects. Holds a B.S. (Henderson State College), M.S. (University of Arkansas), and Ph.D. (Purdue University). Designated “audit committee financial expert” by the Board .

Past Roles

OrganizationRoleTenureCommittees/Impact
Lexicon Pharmaceuticals, Inc.Chairman of the Board2005–2012Board leadership during company development stage
Bristol‑Myers Squibb CompanyEVP, Worldwide Franchise Mgmt & Strategy; President, U.S. Pharmaceuticals; President, Intercontinental Commercial OperationsThrough retirement in 1999Led global/commercial operations across multiple franchises
Clearview Projects, Inc.Co‑founder, President & CEONot disclosedPartnering/transaction services for biopharma clients

External Roles

OrganizationRoleTenureCommittees/Notes
Cyclacel Pharmaceuticals, Inc.DirectorCurrentPublic company board service

Board Governance

AttributeDetail
Board statusIndependent director (Nasdaq standards)
CommitteesAudit Committee (Chair); Compensation Committee (Member)
Financial expertBoard determined Dr. Barker is an “audit committee financial expert”
Board structureClassified board; Class II (current Class II term ends at 2026 annual meeting)
AttendanceIn 2024, no incumbent director attended fewer than 75% of Board/committee meetings during period served

Fixed Compensation (Non‑Employee Director; 2024)

ComponentCompany ScheduleDr. Barker – 2024 Actual ($)
Annual Board retainer50,00050,000
Audit Committee (member / chair)10,000 / 20,00020,000 (Chair)
Compensation Committee (member / chair)7,500 / 15,0007,500 (Member)
Corporate Governance Committee (member / chair)5,000 / 10,000
Total cash fees77,500

Notes:

  • Non‑executive Chairman of the Board retainer: $75,000 (not applicable to Barker) .

Performance Compensation (Non‑Employee Director; 2024)

Award TypeGrant DateQuantityExercise Price / Per‑Share FVGrant Date Fair Value ($)
Stock Options05/13/202444,906$1.7966,161
RSUs05/13/202436,810$1.79 (per‑share grant FV)65,890

Additional equity context:

  • Unexercised stock options held as of 12/31/2024: 114,503 (aggregate) .
  • Non‑employee director plan cap: aggregate grant date fair value of stock awards plus cash fees ≤ $500,000 per calendar year .
  • 2024 director pay mix for Barker: Cash $77,500 vs. Equity $132,051 (approx. 37% cash / 63% equity), aligning incentives with shareholders .

Other Directorships & Interlocks

ItemDetail
Public company boardsCyclacel Pharmaceuticals, Inc. – Director
Compensation committee interlocksNone reported for 2024 (committee members: Amouyal (Chair), Barker, Swain)

Expertise & Qualifications

  • Deep biopharma operating experience across R&D, manufacturing, commercial, and BD from Bristol‑Myers Squibb and Clearview Projects .
  • Board‑designated audit committee financial expert; chairs Audit Committee .
  • Advanced scientific training (Ph.D.) and leadership across global commercial operations .

Equity Ownership

MeasureAmount
Shares beneficially owned (4/3/2025)87,649 (<1% of outstanding)
Shares issuable within 60 days (options exercisable or RSUs scheduled to vest)114,300
Unexercised stock options (12/31/2024)114,503
Hedging/pledging policyCompany policy prohibits hedging and discourages trading options on company stock by directors/officers/employees

Governance Assessment

  • Strengths

    • Independent director; chairs Audit Committee; designated audit committee financial expert—supports robust financial oversight .
    • Solid engagement record: no director (including Barker) fell below 75% attendance in 2024 .
    • Director compensation emphasizes equity (≈63% equity in 2024), and company prohibits hedging—favorable alignment with shareholders .
    • No related‑party transactions involving Barker disclosed; audit committee excludes Invus designees, mitigating conflicts given Invus’ ~49.7% stake and governance rights .
  • Considerations

    • Long tenure (on Board since 2000; former Chairman 2005–2012) can draw investor scrutiny on independence refresh, though the Board affirms independence under Nasdaq standards .
    • Individual ownership is <1% of outstanding shares; while typical for small‑cap biopharma directors, some investors prefer higher personal ownership for enhanced alignment .
    • Broader governance environment: company sought authority for a reverse split to address Nasdaq bid‑price non‑compliance—macro signal relevant to overall investor confidence (not specific to Barker) .
  • Shareholder feedback signals

    • Say‑on‑pay support exceeded 97% in 2024—suggests general shareholder confidence in compensation governance .
  • Compensation process hygiene

    • Non‑employee director compensation benchmarked with independent consultant (Pearl Meyer) in 2023; non‑employee director plan caps annual value; mix of options/RSUs used .