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Catherine Friedman

Lead Independent Director at Lyell Immunopharma
Board

About Catherine Friedman

Catherine Friedman, 64, has served on Lyell Immunopharma’s board since August 2018 and as Lead Independent Director since July 2021. She is an Executive Venture Partner at GV Management Company, LLC and brings nearly 40 years of experience across finance, technology and healthcare; she holds a B.A. in economics from Harvard University and an MBA from UVA Darden . As Lead Independent Director, she presides over executive sessions, leads CEO performance evaluations and succession planning, and acts as liaison for the independent directors .

Past Roles

OrganizationRoleTenureCommittees/Impact
Morgan StanleyManaging Director; Head of West Coast Healthcare; Co-head, Biotechnology practiceNot disclosedSenior investment banking leadership in healthcare/biotech
Altaba Inc. (formerly Yahoo!)DirectorNot disclosedTechnology/finance board experience
Seer, Inc.Independent Director (prior)Not disclosedLife sciences governance
Revolution Healthcare Acquisition Corp.Independent Director (prior)Not disclosedSPAC/healthcare governance
GRAILIndependent Director (prior)Not disclosedOncology diagnostics governance
Vividion TherapeuticsIndependent Director (prior)Not disclosedBiotech governance; company acquired by Bayer
Radius HealthIndependent Director (prior)Not disclosedBiopharma governance

External Roles

OrganizationRoleTenureNotes
GV Management Company, LLCExecutive Venture PartnerCurrentSenior investing team; advises life sciences portfolio
UVA Darden School of BusinessFoundation trusteeCurrentAcademic board role

Board Governance

  • Independence: The Board determined all non-employee directors, including Ms. Friedman, are independent under Nasdaq rules; CEO Dr. Seely is not independent .
  • Board leadership: Chair is Dr. Rick Klausner; Ms. Friedman serves as Lead Independent Director with authority over executive sessions, agendas for independent directors, CEO evaluation, and succession .
  • Attendance: The Board met 8 times in FY2024; all current directors except Mr. Nelsen attended at least 75% of Board and committee meetings during their service periods .
  • Executive sessions: Independent directors typically meet in executive sessions outside of management’s presence at regular Board meetings .
  • Committee membership and 2024 meetings:
CommitteeChairMembersFY2024 Meetings
AuditWilliam RieflinCatherine Friedman; Elizabeth Nabel4
CompensationCatherine FriedmanRobert Nelsen; William Rieflin (Mr. Nelsen to cease at Annual Meeting)6
Nominating & Corporate GovernanceOtis BrawleyElizabeth Nabel; Sumant Ramachandra4
  • Audit committee qualifications: Friedman is designated an “audit committee financial expert” along with Rieflin and Nabel .

Fixed Compensation

  • Non-employee director compensation (FY2024 actual):
ItemAmount
Cash fees (retainers and committee roles)$102,507
Option awards (grant-date fair value)$205,335
Total$307,842
  • Director Compensation Policy (Updated Apr 2024):
ComponentAmount
Annual cash retainer (non-Chair/Lead)$50,000
Lead Independent Director annual retainer$80,000
Chair of Board annual retainer$85,000
Committee chair retainers (Audit/Comp/Nominating)$20,000 / $15,000 / $10,000
Committee member retainers (Audit/Comp/Nominating)$10,000 / $7,500 / $5,000
  • Meeting fees: Not disclosed; reimburse reasonable out-of-pocket expenses for Board/committee meetings .

Performance Compensation

  • Equity awards for directors are stock options under the 2021 Equity Incentive Plan, time-based only; no performance-based equity (RSUs/PSUs) is granted to directors .
Equity ComponentGrant detailsVestingPlanAcceleration
Annual option grant130,000 shares (cap or $300k Black-Scholes) granted on each annual meeting date; June 14, 2024 for FY2024 cohortVests fully by next annual meeting or first anniversary of grant, subject to continued service 2021 Plan Full vesting on Change in Control if in continuous service until immediately prior to closing
  • Risk signal: Company executed a one-time option repricing in Nov 2023 for options with exercise prices >$2.37, resetting to $1.87 and extending vesting schedules for senior executives; Board-approved repricing is often viewed as a governance red flag. No director-specific repricing disclosure, but policy-level action indicates a willingness to modify equity terms .

Other Directorships & Interlocks

CompanyRoleCurrent/PriorPotential Interlock/Notes
Altaba Inc.DirectorPriorTechnology investment vehicle; no Lyell transaction disclosed
Seer, Inc.Independent DirectorPriorNo Lyell related-party transactions disclosed
Revolution Healthcare Acquisition Corp.Independent DirectorPriorSPAC; no Lyell interlocks disclosed
GRAIL; Vividion Therapeutics; Radius HealthIndependent DirectorPriorNo Lyell related-party transactions disclosed
  • Related party transactions: Lyell reports no related person transactions requiring disclosure since Jan 1, 2023 beyond those noted; none involve Ms. Friedman .

Expertise & Qualifications

  • Finance and capital markets leadership (Morgan Stanley MD; biotech coverage) .
  • Board leadership across life sciences and tech, including Altaba/Yahoo! and multiple biopharma companies .
  • Recognized as audit committee financial expert; brings deep financial proficiency to audit oversight .
  • Academic and venture roles (UVA Darden trustee; Executive Venture Partner at GV) reinforcing strategic and governance acumen .

Equity Ownership

HolderShares/OptionsNotes
Catherine Friedman (beneficial)1,301,370<1% of outstanding shares
Breakdown965,000 options exercisable within 60 days; 100,000 shares (Duane Irrevocable Trust 2020); 236,370 shares (Duane Family Trust)Friedman is trustee of Duane Trusts and disclaims beneficial ownership except to any pecuniary interest
Director options outstanding (as of 12/31/2024)965,000For Ms. Friedman
  • Hedging/pledging: Company policy prohibits directors from hedging, pledging, short sales and derivative transactions in Lyell stock, supporting alignment and risk control .

Governance Assessment

  • Strengths:

    • Lead Independent Director role with robust authority (executive sessions, CEO evaluation, succession planning), reinforcing independent oversight .
    • Chair of Compensation Committee with structured processes, use of independent consultants (Aon until July 2024; Alpine thereafter), peer benchmarking, and clawback policy adoption in Sept 2023 .
    • Audit Committee membership and designation as financial expert, bolstering financial controls and risk oversight .
    • Attendance at least 75% in FY2024 for all current directors except one, indicating engagement; Board met eight times .
  • Watch items / RED FLAGS:

    • Board-approved option repricing (Nov 2023) for executives can signal misalignment risk if used to offset poor stock performance; merits monitoring of future equity adjustments .
    • Nasdaq minimum bid price deficiency and proposed reverse stock split (1-for-10 to 1-for-25) to maintain listing; governance should demonstrate credible turnaround and capital discipline to sustain investor confidence .
  • Independence and conflicts:

    • Board deems Ms. Friedman independent; no related-party transactions disclosed involving her; recusal precedent exists for other directors on specific tech matters, evidencing conflict management discipline .
  • Director pay and alignment:

    • Mix of cash retainers and time-based options; Lead Independent Director and Compensation Chair retainers elevate cash component; option vesting is short-dated to next annual meeting, supporting refresh but not performance linkage .
    • Beneficial ownership is <1%; policy restrictions on hedging and pledging support alignment despite low ownership percentage .