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Robert Nelsen

Director at Lyell Immunopharma
Board

About Robert Nelsen

Independent director of Lyell Immunopharma since September 2018; age 60 as of March 31, 2024. Co‑founder and Managing Director of ARCH Venture Partners (since 1986), with extensive board experience across biotech; current boards include Brii Biosciences, Prime Medicine, Sana Biotechnology, and Vir Biotechnology; Chairman of Hua Medicine. Education: MBA (University of Chicago); BS (University of Puget Sound, Economics and Biology) .

Past Roles

OrganizationRoleTenureCommittees/Impact
ARCH Venture PartnersCo‑founder, Managing DirectorSince 1986Led investments; extensive board-building in life sciences
Adolor; Agios; Beam; Bellerophon; Denali; Fate; Gossamer; Illumina; Juno; Karuna; Kythera; NeurogesX; Receptos; Revolution Healthcare Acquisition; Sage; Sienna; Syros; UnityDirector (prior)Various years (as disclosed)Broad biotech governance experience
Fred Hutchinson Cancer Research Center; Institute for Systems BiologyTrustee (prior)Not disclosedNon-profit governance in biomedical research
National Venture Capital AssociationDirector (prior)Not disclosedIndustry advocacy and governance

External Roles

OrganizationRolePublic/PrivateNotes
Altos Labs, Inc.DirectorPrivateAffiliation triggered LYEL board recusals on specific topics
Brii BiosciencesDirectorPublicCurrent board service
Prime MedicineDirectorPublicCurrent board service
Sana BiotechnologyDirectorPublicCurrent board service
Vir BiotechnologyDirectorPublicCurrent board service
Hua MedicineChairmanPublicCurrent chair role

Board Governance

  • Committee memberships: Compensation Committee member in FY2024; effective as of the May 15, 2025 annual meeting, Nelsen will cease serving on the Compensation Committee .
  • Independence: Board determined all non-employee directors (including Nelsen) are independent under Nasdaq rules; only CEO is non‑independent in 2025 (previously CEO and former Executive Chair were non‑independent in 2024) .
  • Attendance: Board met eight times in FY2024; all current directors except Nelsen attended at least 75% of board/committee meetings—indicates sub‑threshold attendance for Nelsen (red flag) .
  • Conflicts management: Nelsen and Board Chair Klausner recused from board/committee discussions related to T‑cell rejuvenation technology due to Altos Labs affiliations .

Fixed Compensation

YearCash Fees ($)Committee Fees IncludedTotal Cash ($)
202456,820Yes (member fees embedded in total director cash)56,820
202356,000Yes56,000
  • Non‑Employee Director Compensation Policy: Annual cash retainers—$50,000 for directors; $80,000 for Lead Independent Director; Committee chair/member cash retainers increased in April 2024 to $15,000/$7,500 (Comp), $20,000/$10,000 (Audit), $10,000/$5,000 (Nom/Gov) .

Performance Compensation

YearEquity TypeGrant DateSharesGrant‑Date Fair Value ($)Vesting
2024Stock OptionsJun 14, 2024130,000205,335100% vest by next annual meeting or 1st anniversary, subject to service
2023Stock OptionsJun 16, 202365,000Part of 230,745Standard annual grant under prior policy
2023 (supplemental)Stock OptionsSep 8, 202355,000Part of 230,745To align with updated 2023 policy; same vesting schedule
  • Change‑of‑control terms for directors: All outstanding director equity vests fully immediately prior to closing (single‑trigger acceleration) if the director remains in continuous service until immediately prior to the change‑in‑control .
  • No performance‑based equity disclosed for directors (PSUs/RSUs not part of director program) .

Other Directorships & Interlocks

CategoryDetail
Compensation committee interlocksNone disclosed for FY2023 (committee included Friedman, Nelsen, Rieflin) .
Network overlapsAltos Labs affiliations (Nelsen and Klausner; Bishop previously) required recusals on LYEL T‑cell rejuvenation technology—managed via board process .

Expertise & Qualifications

  • Venture capital leadership (ARCH Venture Partners co‑founder/MD), extensive company formation and board governance across biotech and pharma .
  • Degrees in economics and biology (BS), MBA; cross‑disciplinary expertise valuable for compensation, capital markets, and R&D portfolio oversight .

Equity Ownership

HolderBeneficial Shares% OutstandingComponents/Notes
Robert Nelsen36,727,71612.4%Includes 315,000 options exercisable within 60 days; as AVP IX Managing Director, may be deemed to beneficially own ARCH Venture Fund IX and Overage holdings; Nelsen disclaims beneficial ownership except to pecuniary interest
ARCH Venture Partners (affiliated entities)36,412,71612.3%AVF IX and AVF IX Overage shares; control relationships disclosed among AVP entities and managing directors (incl. Nelsen)
  • Insider Trading Policy: Prohibits hedging, margin purchases, pledging, short sales and derivative transactions in LYEL stock—reduces alignment risks from hedging/pledging (policy applies to directors) .

Governance Assessment

  • Strengths: Deep biotech governance and venture experience; independent status; committee experience on compensation; robust related‑party/recusal practices documented; director equity aligns interests; strict prohibitions on hedging/pledging .
  • Red flags and investor confidence signals:
    • Attendance shortfall: Did not meet ≥75% attendance in FY2024—questions on engagement (critical governance concern) .
    • Concentrated ownership via ARCH affiliations: Significant influence (12%+ beneficial ownership) may pose perceived conflicts; disclosure and disclaimers mitigate, but monitor voting and committee roles .
    • Change‑of‑control single‑trigger vesting for directors: Potential misalignment in takeover scenarios (common practice but not shareholder‑friendly) .
  • Near‑term signal: Stepping off the Compensation Committee effective May 15, 2025 (reduce direct influence over exec/director pay) .

Overall, Nelsen brings valuable industry and capital markets expertise, but attendance and influential ownership/interlocks warrant continued monitoring. Active recusals and established related‑party review processes are positives for board effectiveness .