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Vlad Vitoc

Vlad Vitoc

Chief Executive Officer and President at MAIA Biotechnology
CEO
Executive
Board

About Vlad Vitoc

  • Chairman, President & CEO of MAIA Biotechnology; age 55; co‑founder; serving as CEO/Chairman since September 2018. Education: M.D. (University of Medicine and Pharmacy “Iuliu Hațieganu”, Cluj‑Napoca) and MBA (University of South Carolina) .
  • Company status/performance context: MAIA is pre‑revenue and disclosed substantial doubt about going concern without additional financing; cash was $10.9M and working capital ~$1.76M as of 9/30/25 .
  • Execution highlights under Vitoc: Phase 2 THIO‑101 in 3L NSCLC reported estimated median OS of 17.8 months (95% CI lower bound 12.5; 99% CI 10.8) in the ITT cohort; FDA granted Fast Track for ateganosine (THIO) in NSCLC; Phase 3 THIO‑104 (vs chemo, ~300 patients) planned to initiate 2025 .

Past Roles

OrganizationRoleYearsStrategic impact
Multiple biotech/pharma companiesCommercial strategy and medical affairs leadership roles~20 yearsManaged/supported 20+ early/launch/mature compounds across >25 tumor types (e.g., CRC, HCC, lung, breast, prostate, renal)

External Roles

  • No external public company board roles for Dr. Vitoc are listed in MAIA’s 2024 or 2025 proxy disclosures .

Fixed Compensation

Multi‑year CEO compensation (Summary Compensation Table):

YearSalaryBonusOption Awards (grant‑date FV)All Other CompensationTotal
2024$473,000 $236,500 (accrued; expected to be paid in 2025) $637,480 $13,461 $1,360,441
2023$473,000 $0 $900,934 $12,306 $1,386,240
2022$442,542 $236,500 $492,220 $36,508 $1,207,770

Notes:

  • Current (effective Feb 1, 2025) base salary increased to $625,000; target annual bonus up to 55% of base; see Employment Terms below .

Performance Compensation

Annual incentive structure and equity awards:

  • Annual cash incentive (short‑term)

    • Design: Discretionary, based on individual performance objectives, corporate goals, and milestone achievements set by the board .
    • Target: Up to 55% of base salary under 2025 agreement (prior 2022 agreement was up to 50%) .
    • 2024 outcome: $236,500 accrued; board disclosed bonuses expected to be paid in 2025 .
  • Stock options (long‑term)

    • Plan: 2021 Equity Incentive Plan; options priced at or above grant‑date fair value; 10‑year term; no PSUs disclosed for NEOs .
    • 2024 option grants to Vitoc (unvested as of 12/31/24):
      • 200,000 options @ $1.41 (1/24/2024), expires 1/24/2034
      • 200,000 options @ $2.94 (4/26/2024), expires 4/26/2034
    • Other outstanding awards (selection):
      • 87,501 exercisable / 112,499 unexercisable @ $4.10 (3/08/2023); expires 3/08/2033
      • 112,501 exercisable / 87,499 unexercisable @ $3.56 (9/16/2022); expires 9/16/2032
      • Legacy grants: e.g., 805,000 ex. @ $1.80 (10/01/2018) exp. 9/30/2028; 705,789 ex. @ $1.80 (11/03/2020) exp. 11/02/2030 .

Detailed outstanding CEO equity (as of 12/31/24):

Grant DateExercisable (#)Unexercisable (#)Exercise PriceExpiration
04/26/2024200,000 $2.94 04/26/2034
01/24/2024200,000 $1.41 01/24/2034
05/31/2023123,760 $2.50 05/31/2033
03/08/202387,501 112,499 $4.10 03/08/2033
09/16/2022112,501 87,499 $3.56 09/16/2032
07/01/20217,529 $1.83 06/30/2031
04/16/2021509,906 $1.83 04/15/2031
04/01/202123,078 $1.83 03/31/2031
01/01/202123,695 $1.80 12/31/2031
11/03/2020705,789 $1.80 11/02/2030
04/01/2020169,500 $1.80 03/31/2030
10/01/2018805,000 $1.80 09/30/2028

Notes: Certain options were transferred to children’s trusts; Vitoc retains beneficial ownership of a portion (e.g., 300,000 transferred; 200,000 beneficial; 59,945 transferred; 39,963 beneficial) .

Equity Ownership & Alignment

  • Beneficial ownership and composition:
Record DateTotal Beneficial Ownership% of ClassDirect/Common Shares (incl. spouse)Options/Warrants exercisable within 60 days
Mar 24, 20253,610,383 11.22% 1,019,221 (incl. 210,100 spouse) 2,591,162 (incl. 28,159 spouse; 322,470 in daughters’ trusts)
Mar 28, 20243,459,015 15.03% 1,019,121 (incl. 210,000 spouse) 2,439,894 (2,438,083 options + 1,811 warrants)
  • Hedging/pledging: Company prohibits hedging/short sales; pledging requires pre‑clearance; as of 12/31/24, no directors/executive officers had pledged shares .
  • Rule 10b5‑1: Directors/executive officers had plans to buy shares; as of 11/7/25 those plans had expired; future plans may be adopted .
  • Ownership guidelines: Not disclosed in proxy/10‑Q .

Employment Terms

ItemTerms
Agreement dateFebruary 1, 2025 (amendment of prior agreement)
Base salary$625,000
Target annual bonusUp to 55% of base salary; discretionary, tied to individual and corporate milestones
Severance (no Change‑of‑Control)If terminated without Cause or resigns for Good Reason: 12 months base salary; accelerate unvested equity that would have vested in 12 months; up to 12 months COBRA at active‑rate cost share; release required
Change‑of‑Control (double trigger; within 180 days post‑CoC)Lump sum 18 months base salary + 1.5× target bonus; full acceleration of all unvested equity; up to 18 months COBRA at active‑rate cost share; release required
Restrictive covenantsInvention assignment/confidentiality; non‑compete and non‑solicit during employment and 12 months post‑termination
Prior terms (Sept 16, 2022 agreement)Base salary $473,000; target bonus up to 50%; similar severance constructs

Board Governance (director‑specific)

  • Roles: Chairman of the Board (combined CEO/Chair structure). Board determined combined roles are in stockholders’ best interests; Lead Independent Director is Dr. Stan V. Smith .
  • Independence: Board deems all directors independent except Dr. Vitoc (CEO) .
  • Committees: Audit (Louie—Chair; Chaouki; Smith), Compensation (Smith—Chair; Luput; Guerrero), Nominating & Governance (Louie—Chair; Luput; Smith) .
  • Board structure/tenure: Classified board (3 classes). Vitoc is Class II (term to 2027) .
  • Attendance: Board held 4 meetings in 2024 with full attendance .
  • Director pay: Employee director (Vitoc) receives no additional compensation for board service per policy .

Related Party/Transactions Context (governance)

  • Director participation in private placements during 2024 (e.g., Smith, Louie, Luput, Chaouki, Guerrero) with warrants issued; structured via 2021 Plan as unrestricted stock awards and options; not deemed compensatory by company; details and terms disclosed .
  • Indemnification: Company provides indemnification and D&O insurance; separate indemnification agreements in place .

Risk Indicators & Red Flags

  • Financial risk: Company disclosed substantial doubt about going concern; continued operating losses; need for additional capital .
  • Digital asset treasury plan: Board authorized up to 90% of corporate treasury in BTC/ETH/USDC; as of 11/7/25 no purchases yet; filings highlight regulatory/liquidity/volatility risks associated with crypto .
  • Hedging/pledging policy: Anti‑hedging and pledging restrictions reduce misalignment risk; no pledging by insiders as of 12/31/24 .
  • Legal/SEC: No material legal proceedings involving directors/officers; Section 16 compliance timely for 2024 .

Performance & Track Record (company under Vitoc)

  • THIO‑101 (Phase 2, 3L NSCLC): Estimated median OS 17.8 months (95% CI lower bound 12.5; 99% CI 10.8); partial response noted after ~20 months in one patient; treatment generally well‑tolerated in heavily pre‑treated population .
  • FDA Fast Track granted for ateganosine (THIO) in NSCLC (July 2025) .
  • Phase 3 THIO‑104 planned for 2025; direct comparison vs chemotherapy; ~300 patients; 1:1 randomization .

Investment Implications

  • Alignment: High insider ownership (11.22% of shares; significant portion via long‑dated options) aligns CEO incentives with equity value creation and regulatory/clinical milestones; anti‑hedging and no pledging further align interests .
  • Pay‑for‑performance: 2025 contract lifts base salary to $625k with higher at‑risk target (55%); equity grants are option‑heavy (no PSUs disclosed), tying upside to stock appreciation; 2024 cash bonuses accrued despite cash management constraints, but were structured for payment in 2025 .
  • Retention/CoC: Double‑trigger CoC package (18 months salary + 1.5× target bonus + full equity vesting) is sizable for a micro‑cap biotech and could be dilutive in a sale, but supports stability through pivotal trials .
  • Overhang/over‑time supply: Large unexercised/unvested option stack with expirations into 2034 may create future dilution; vesting specifics beyond status at 12/31/24 were not disclosed .
  • Funding/runway risk: Going‑concern language and recurring equity financings (ATM/private placements) remain core risks; newly adopted digital asset strategy adds treasury volatility/regulatory risk, which investors may discount .
Overall: Vitoc’s high ownership and option‑based incentives are aligned with value creation from Phase 2/3 execution, but funding dependence, crypto‑treasury optionality, and a generous CoC package are key governance and risk considerations ahead of pivotal milestones **[1878313_0001140361-25-012689_ny20041469x2_def14a.htm:24]** **[1878313_0001140361-25-012689_ny20041469x2_def14a.htm:28]** **[1878313_0001140361-25-012689_ny20041469x2_def14a.htm:31]** **[1878313_0001493152-25-021272_form10-q.htm:7]** **[1878313_0001493152-25-021272_form10-q.htm:30]**.