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James Cornelius

Director at MBX Biosciences
Board

About James M. Cornelius

James M. Cornelius (age 81) is an independent Class II director of MBX, serving since September 2020; his current term expires at the 2026 annual meeting. He chairs the Audit Committee and sits on the Compensation Committee, and the board has designated him as an “audit committee financial expert.” He holds a B.A. magna cum laude and an M.B.A. from Michigan State University and has previously served as CFO, CEO, and Chair at multiple public companies.

Past Roles

OrganizationRoleTenureCommittees/Impact
Bristol Myers Squibb (NYSE: BMY)ChairmanFeb 2008–May 2015Led board oversight for large-cap biopharma
Bristol Myers SquibbCEOSep 2006–Mar 2010Operational leadership and capital allocation
Mead Johnson Nutrition (acq. by Reckitt Benckiser)ChairmanDec 2009–Jun 2017Governance of nutrition company pre-sale
Guidant (acq. by Boston Scientific)Chairman & CEONov 2005–Apr 2006Turnaround/strategic transaction leadership
GuidantExecutive Chairman & Senior ExecutiveFrom Sep 1994Built medtech business spun from Eli Lilly
Eli Lilly (NYSE: LLY)CFO and Director1983–1995Principal financial/accounting officer experience
The Chubb CorporationDirectorNot disclosedPrior public board service
The DIRECTV GroupDirectorNot disclosedPrior public board service
Given ImagingDirectorNot disclosedPrior public board service

External Roles

OrganizationRoleTenureNotes
Cornelius Family FoundationChairmanCurrentPhilanthropy leadership
Cornelius Private InvestmentsChairmanCurrentPrivate investment leadership

Board Governance

  • Board status and class: Independent Class II director; term to 2026 annual meeting.
  • Committees: Audit Committee Chair; Compensation Committee member; all audit committee members are independent and financially literate; Cornelius is the board-designated “audit committee financial expert.”
  • Lead independent director: Patrick J. Heron.
  • Independence: Board determined all directors except the CEO are independent per Nasdaq/SEC rules.
  • Attendance: Board met seven times in 2024; each director attended at least 75% of board and committee meetings.
  • Committee activity: Audit and Compensation Committees established in Aug 2024; each held one meeting in FY 2024.

Fixed Compensation

ComponentAmountPeriod/ContextSource
Fees Earned (Cash)$17,446FY 2024 actual
Board Annual Cash Retainer (policy)$40,000Policy adopted Sept 2024
Audit Committee Chair Retainer (policy)$15,000Policy
Compensation Committee Member Retainer (policy)$5,000Policy
Lead Independent Director Retainer (policy)$20,000Not applicable to Cornelius

Note: Policy cash retainers are payable quarterly and prorated for partial years.

Performance Compensation

MetricAmount/DetailPeriod/ContextSource
Option Awards (grant-date fair value)$349,283FY 2024 actual
Director Annual Option Grant (policy)16,000 optionsGranted at each annual meeting; vests in full by next annual meeting or 1 year
Director Initial Option Grant (policy)32,000 optionsFor new directors; vests over 3 years (1/3 at year 1, remainder monthly)
Outstanding Director Options55,240 sharesAs of Dec 31, 2024 (aggregate options held)
Options Exercisable ≤60 Days39,277 sharesAs of April 11, 2025

Vesting terms (policy): Annual grants vest in full within one year (or by next annual meeting); initial grants vest 1/3 at year one, remainder monthly over 24 months; full acceleration upon sale of the company.

Other Directorships & Interlocks

CompanyRoleInterlock/Notes
Bristol Myers SquibbFormer Chairman/CEOPrior role; no current interlock disclosed
Mead Johnson NutritionFormer ChairmanPrior role; company acquired by Reckitt Benckiser
GuidantFormer Chairman/CEOPrior role; company acquired by Boston Scientific
Eli LillyFormer CFO and DirectorPrior role
The Chubb Corporation; The DIRECTV Group; Given ImagingFormer DirectorPrior roles
  • MBX major holders have board representation (e.g., Frazier, OrbiMed, NEA, Norwest), but the board determined Cornelius is independent; audit/comp committees meet SEC/Nasdaq independence requirements.

Expertise & Qualifications

  • Designated audit committee financial expert; prior service as principal financial officer, principal executive officer, and principal accounting officer at public companies.
  • Deep biopharma and medtech leadership; extensive public board experience.
  • Education: B.A. magna cum laude and M.B.A. from Michigan State University.

Equity Ownership

CategorySharesPercent of OutstandingNotes
Common Shares Held102,082<1%Direct holdings
Options Exercisable ≤60 Days39,277<1%Early-exercise options immediately exercisable within 60 days as of 4/11/2025
Total Beneficial Ownership141,359<1%Based on 33,424,371 shares outstanding

Policy on hedging/derivatives and pledging: Short sales and derivative transactions prohibited; pledging requires Audit Committee advance approval. No pledges by Cornelius disclosed.

Governance Assessment

  • Strengths: Independent director; Audit Committee Chair with “financial expert” designation; committees follow SEC/Nasdaq independence standards; attendance at or above required thresholds; formal clawback policy adopted per SEC/Nasdaq. These factors support board effectiveness and investor confidence.
  • Alignment: Holds common shares and near-term exercisable options; receives equity via standardized director option policy (annual grants), indicating equity-based alignment with shareholder outcomes.
  • Compensation structure: Modest cash fees in 2024, with equity as the larger component; policy cash retainers/committee fees are transparent and prorated post-IPO, reducing pay opacity.
  • Potential risks/considerations: Venture investors hold significant stakes and board seats (Frazier, OrbiMed, NEA, Norwest), creating potential ecosystem interlocks; however, Cornelius is unaffiliated with these holders and the Audit Committee reviews/approves related-person transactions per policy. Age 81 may raise long-term continuity considerations, but tenure and expertise provide stabilizing oversight.
  • Related-party exposure: Participated in Series B via conversion of a convertible note ($188,886.33 → 233,192 shares) during 2022–2023 financing rounds; disclosed in “Certain relationships and related transactions.” No additional transactions above thresholds since Jan 1, 2023 other than disclosed financings.

Director Compensation Policy Details (Reference)

Policy ElementAmount/TermsSource
Board Annual Retainer$40,000
Audit Chair$15,000
Audit Member$7,500
Compensation Chair$10,000
Compensation Member$5,000
Nominating/Gov Chair$8,000
Nominating/Gov Member$4,000
Science & Medicine Chair$8,000
Science & Medicine Member$4,000
Lead Independent Director$20,000
Non-Executive Chair$30,000
Director Initial Option Grant32,000 options; 3-year vest (1/3 at year 1; remainder monthly)
Director Annual Option Grant16,000 options; vests within 1 year/by next annual meeting
Annual Equity/Cash Cap$750,000 (or $1,000,000 first year as director)

Compliance and Related-Party Controls

  • Related-party transactions: No transactions above thresholds since Jan 1, 2023 other than disclosed financing activity; policy mandates Audit Committee approval for related-party transactions.
  • Insider trading/hedging/pledging policy: Robust prohibitions and pre-approval requirements; insider trading policy filed with 10-K as Exhibit 19.1.
  • Board leadership: CEO also Chair with a Lead Independent Director structure; independent directors meet in executive session frequently.

RED FLAGS

  • None disclosed for Cornelius on hedging or pledging; no loans or undisclosed related-party transactions. Prior participation in financing via note conversion is disclosed and customary for pre-IPO investors/insiders. Concentrated ownership and multiple investor-affiliated directors warrant ongoing monitoring, but independence determinations and Audit Committee oversight mitigate conflict risk.