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Paul Biondi

Director at Seres TherapeuticsSeres Therapeutics
Board

About Paul R. Biondi

Independent Class III director at Seres Therapeutics (MCRB) since March 2020; age 55; current term ends at the 2027 annual meeting . Managing Partner and President of Pioneering Medicines at Flagship Pioneering since November 2019; previously Senior Vice President, Strategy & Business Development at Bristol‑Myers Squibb (2015–2019) following earlier R&D leadership roles (2002–2015) . Education: BA, Dartmouth College; MBA, Northwestern University (Kellogg) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Bristol-Myers SquibbSVP, Strategy & Business Development; earlier R&D leadership overseeing strategy, portfolio, project mgmt., clinical & business operations2002–2019 (SVP S&BD 2015–2019)Corporate strategy/M&A and R&D portfolio leadership

External Roles

OrganizationRoleTenureNotes
Flagship PioneeringManaging Partner; President, Pioneering MedicinesNov 2019–PresentFlagship conceives, builds, and funds biotech platforms

Board Governance

  • Independence: Board determined all directors except CEO are independent under Nasdaq rules; for Biondi and Berenson, the Board specifically considered their relationship to Flagship Pioneering and related transactions and still deemed them independent .
  • Committee assignments (2024): Member, Compensation & Talent Committee (6 meetings in 2024; Chair: Kurt C. Graves) .
  • Attendance: Board met 6 times in 2024; each director attended at least 75% of Board and committee meetings; all then‑incumbent directors attended the 2024 annual meeting .
  • Board structure: Classified board (3 classes); Chair of the Board is Stephen A. Berenson (also a Flagship executive) .
  • ESG/governance processes: Annual board evaluation overseen by Nominating & Corporate Governance; outside counsel interviews; existence of Code of Conduct and Clawback policy .
  • Key shareholder governance signals: 2024 say‑on‑pay support ~65% of votes cast (modest) .

Fixed Compensation

ComponentAmountDetail
Fees Earned (Cash) – 2024$65,625As reported in Director Compensation table
Base annual director fee$45,000Program terms (effective Mar 19, 2024)
Compensation & Talent Committee member fee$7,500Program terms
Chair/Lead independent director premium$35,000Not applicable to Biondi; program terms
Other committee member feesAudit $10,000; Nominating $5,000; Science $7,500Program terms

Notes:

  • Some directors elected to receive options in lieu of cash fees for the July 1, 2024–June 30, 2025 period; Biondi is not listed among those who elected equity in lieu of cash .

Performance Compensation

Equity Element2024 Grant Date Fair ValueVesting/TermsPerformance Metrics
Stock Options (annual director grant)$38,748Annual option typically vests in a single installment by next annual meeting or 1-year anniversary; fair market value exercise price; full vest on change in control if not assumed None disclosed for director awards (time-based only)

Additional plan mechanics:

  • Initial director option: 120,000 options upon joining (effective Mar 19, 2024 change); annual “subsequent” option: 60,000 .
  • 2025 Incentive Award Plan prohibits repricing without stockholder approval, sets a $750,000 annual director compensation cap ($1,000,000 first-year), removes evergreen, and continues no single-trigger acceleration unless awards not assumed in a change-in-control .

Other Directorships & Interlocks

CategoryDetail
Current public company boardsNone disclosed for Biondi in the proxy
Notable affiliationsExecutive at Flagship Pioneering; entities affiliated with Flagship hold ~13.3% of MCRB shares (significant shareholder)
Compensation committee interlocksNone; no MCRB executive served on a board/committee of an entity whose executive served on MCRB’s Comp Committee in 2024

Expertise & Qualifications

  • Biopharmaceutical strategy, corporate development, portfolio and clinical operations leadership from Bristol‑Myers Squibb .
  • Company-building/investing experience via Flagship Pioneering .
  • Education: BA (Dartmouth); MBA (Kellogg) .

Equity Ownership

HolderCommon SharesOptions Exercisable within 60 daysTotal Beneficial Ownership% Outstanding
Paul R. Biondi47,619213,000260,619<1%
Citations: values as of Feb 13, 2025 record date; 174,107,525 shares outstanding . Breakdown footnote: 47,619 shares plus 213,000 options exercisable within 60 days .

Additional alignment/policies:

  • Anti‑hedging and anti‑pledging policy prohibits directors from hedging or pledging company stock; mitigates misalignment and collateral risk .
  • Beneficial ownership by entities affiliated with Flagship Pioneering totals 23,117,045 shares (13.3%)—relevant given Biondi’s and the Board Chair’s Flagship roles .

Governance Assessment

Strengths

  • Independent status affirmed despite Flagship affiliations; committee service on Compensation & Talent indicates active governance engagement (6 meetings in 2024) .
  • Robust director equity program and optional equity-in-lieu features align with long-term value; plan governance safeguards (no repricing, fixed pool, director cap) .
  • Anti‑hedging/pledging and Board-level clawback framework (for executives) support investor alignment and accountability .

Risks/Watch items

  • Potential influence/optics risk: Flagship is a significant shareholder (13.3%) while both the Board Chair and Biondi are Flagship executives; the Board considered these relationships in independence determinations, but investors may scrutinize related‑party oversight and strategic decisions for conflicts .
  • Shareholder sentiment: Say‑on‑pay support of ~65% in 2024 suggests investor concerns on pay/performance; while not director pay-specific, it’s a governance signal .
  • Capital structure/governance pressures: Company pursuing reverse stock split to address Nasdaq bid-price deficiency; going‑concern commentary and financing needs increase governance salience (board oversight of capital and dilution) .

Potential conflicts/related-party exposure

  • Nestlé/SPN relationship (board designate, related-party reimbursement of $0.5M under Employee Support Agreement tied to VOWST business sale) underscores the need for strong Audit Committee oversight; not specific to Biondi but relevant to overall board conflict management .
  • Related person transaction policy requires Audit Committee review; directors recuse if related .

Overall implication for investors

  • Biondi brings deep BD/M&A and portfolio expertise suited to capital-constrained, partnering-heavy phases. However, concentrated Flagship influence plus modest say‑on‑pay support warrant ongoing monitoring of board independence in executive pay, capital raises, and strategic transactions .