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Federica O'Brien

Director at MACROGENICSMACROGENICS
Board

About Federica O’Brien

Federica O’Brien, age 67, has served on MacroGenics’ Board since February 2021. She is a CPA (inactive) with 25+ years of financial and operational leadership across biopharma, medical device, and tech; she began her career in public accounting (Coopers & Lybrand) and most recently founded CFO’Brien Consulting, LLC in 2018 providing strategic/CFO services to biotech companies . MacroGenics’ Board has affirmatively determined she is independent under Nasdaq rules; she is designated an “audit committee financial expert” and chairs the Audit Committee .

Past Roles

OrganizationRoleTenureCommittees/Impact
CFO’Brien Consulting, LLCPresident2018–presentStrategic and flex-time CFO services for biotech
Complexa Inc.Chief Financial Officer2015–2017Finance leadership at clinical-stage company
Cerecor Inc.Chief Financial Officer2013–2015Public company CFO experience
Cervilenz, Inc.Chief Financial Officer & Chief Operating Officer2011–2013Dual CFO/COO responsibilities
Cardiokine Inc.Chief Financial OfficerNot disclosedCFO at private biotech
Barrier Therapeutics, Inc.ControllerNot disclosedController at a public company
Infonautics, Inc.Chief Financial OfficerNot disclosedPublic company CFO
Coopers & LybrandAudit ManagerNot disclosedPublic accounting foundation

External Roles

OrganizationRoleTenureCommittees/Impact
TELA Bio, Inc.DirectorNot disclosedChairs Audit Committee

Board Governance

  • Committee assignments: Audit Committee (Chair), Human Capital Management Committee (member) .
  • Independence: Independent director; all Board committees composed entirely of independent directors per Nasdaq/SEC rules .
  • Audit expertise: O’Brien designated as an “audit committee financial expert” with requisite financial sophistication .
  • Attendance and engagement: In 2024, the Board met 13 times; Audit and Nominating & Corporate Governance each met 4 times; HCMC met 7 times; Science & Technology met 5 times; all directors attended ≥75% of Board/committee meetings and attended the Annual Meeting .
  • Risk oversight: Audit Committee oversees major financial risk exposures, compliance, and cybersecurity; HCMC monitors compensation risk; Nominating & Governance oversees ESG and governance .

Fixed Compensation

ComponentAmountDetails
Annual Board retainer (cash or options)$45,000Non-employee director program (effective pre-May 2025)
Audit Committee – member retainer$10,000Paid in quarterly installments (cash or options)
Audit Committee – chair add’l retainer$20,000Total Audit fees imply $30,000 when chairing
Human Capital Mgmt Committee – member retainer$7,500Paid quarterly (cash or options)
2024 Cash fees actually paid (O’Brien)$82,500Implied sum of retainer + Audit chair/member + HCMC member

Performance Compensation

  • Annual equity awards to directors (time-based, not performance-based):
    • 2024 RSUs: 6,500 units granted to each non-employee director at grant-date fair value $27,690; RSUs vest annually over 1 year (Annual RSU) or equally over 3 years (Initial RSU) .
    • 2024 Options: aggregate grant-date fair value $60,443; Annual Option typically vests monthly over 12 months; Initial Option vests monthly over 36 months; exercise price set at grant-date fair market value .
  • 2025 program changes (effective May 2025): Initial Option 44,000 shares; Annual Option 22,000 shares; Initial RSU 7,500; Annual RSU 3,750 .
Equity Compensation (2024)Units / $VestingValuation Basis
RSUs (O’Brien)6,500 units; $27,690Annual vest; Initial RSU vests over 3 years; Annual RSU vests after ~1 yearGrant-date fair value per ASC 718
Options (O’Brien)$60,443 (fair value)Initial Option: 1/36 monthly; Annual Option: 1/12 monthlyBlack-Scholes; strike = FMV at grant

Other Directorships & Interlocks

CompanySectorRoleNotes
TELA Bio, Inc.Medical deviceDirector & Audit ChairExternal public board service; distinct sector from MacroGenics
  • Interlocks: No disclosed interlocks with MacroGenics’ competitors/suppliers/customers; HCMC interlocks/insider participation section reports no relationships requiring Item 404 disclosure among committee members .

Expertise & Qualifications

  • CPA (inactive) and seasoned finance operator; prior CFO/COO roles across public and private companies .
  • Audit Committee Financial Expert designation; deep financial literacy and governance experience .
  • Education: B.A. in Accounting, Rutgers University .

Equity Ownership

MetricValueNotes
Shares owned directly4,500Beneficial ownership table
Shares issuable within 60 days129,080Options exercisable and RSUs vesting within 60 days
Total beneficial ownership133,580Sum of owned + issuable
Ownership % of outstanding<1%Per table designation
Unvested stock awards (as of 12/31/2024)6,500Unvested RSUs outstanding
Options outstanding (as of 12/31/2024)122,580Shares subject to outstanding options
Stock ownership guidelinesDirectors must hold ≥3x annual retainer; 5-year compliance windowApplies to Board, CEO, Section 16 officers
Pledging/HedgingNot disclosedNo pledging/hedging disclosures identified in proxy

Governance Assessment

  • Strengths: Independent Audit Chair with audit expert designation; strong attendance; transparent and modest director pay framework; clear equity vesting structures; robust clawback policy for awards under the Amended 2023 Plan; prohibition on repricing; no single-trigger CIC vesting; no related party transactions above $120,000 since 2023 .
  • Alignment: Equity grants (options/RSUs) align director interests with shareholders; Board stock ownership guidelines (3x retainer) promote “skin-in-the-game” with reasonable compliance horizon .
  • Shareholder sentiment: Most recent say-on-pay approval at 95.7%, indicating strong investor support for compensation policies (though executive-focused, it signals broader governance confidence) .
  • Potential conflicts/red flags: None disclosed; no Item 404 related party transactions; no evidence of stock pledging or hedging; compensation program prohibits option repricing and dividend equivalents on unvested awards; awards subject to clawback .
  • Attendance signal: All directors met ≥75% meeting attendance threshold and attended the Annual Meeting in 2024, supporting engagement .

RED FLAGS: None identified in disclosures regarding conflicts, related-party transactions, option repricing, pledging/hedging, or low attendance .

Appendix – Program Terms (for context)

  • Director fees (effective pre-May 2025): Board retainer $45,000; Chair add’l $35,000; Committee annual retainers: Audit $10,000 (member) +$20,000 (chair add’l); HCMC $7,500 (member) +$15,000 (chair add’l); Nominating $5,000 +$10,000; Science & Tech $10,000 +$20,000 .
  • Equity vesting mechanics: Options at FMV; Initial Option monthly vest over 36 months; Annual Option monthly vest over 12 months; Initial RSU equal annual vest over 3 years; Annual RSU 1-year vest .
  • Plan governance protections: No single-trigger CIC vesting; prohibition on repricing; dividends not paid on unvested awards; clawback policy adopted February 2021; no discounted options/SARs .

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