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Glenn P. Sblendorio

Chairman at Mineralys Therapeutics
Board

About Glenn P. Sblendorio

Glenn P. Sblendorio (age 69) is Chairman of the Board at Mineralys Therapeutics (MLYS) and has served as a director since September 2023; he is currently nominated for re-election as a Class II director for a term expiring at the 2028 annual meeting if elected . He is a seasoned biotech operator and director: former CEO and director of IVERIC bio (acquired by Astellas in July 2023), former President/CFO and director at The Medicines Company, former CFO of Eyetech Pharmaceuticals, and a former Managing Director at MPM Capital; he holds a B.B.A. (Pace), an M.B.A. (Fairleigh Dickinson), and completed Harvard’s Advanced Management Program .

Past Roles

OrganizationRoleTenureCommittees/Impact
IVERIC bio, Inc. (f/k/a Ophthotech)Chief Executive Officer; DirectorJul 2017 – Jul 2023 (acquired by Astellas Jul 2023)Led company to sale to Astellas .
The Medicines CompanyPresident & CFO; DirectorCFO/President Mar 2006 – Mar 2016; Director Jul 2011 – Dec 2015Senior finance/operator roles; board experience .
Eyetech Pharmaceuticals, Inc.EVP & Chief Financial OfficerFeb 2002 – Nov 2005 (acquired by OSI Pharmaceuticals Nov 2005)Drove finance through sale to OSI .
MPM Capital AdvisorsManaging Director1998 – 2000Investment/biopharma finance experience .

External Roles

OrganizationRoleTenureCommittees/Notes
Amicus Therapeutics, Inc.DirectorCurrentPublic company directorship .
Nanoscope Therapeutics, Inc.DirectorCurrentPublic company directorship .
Intercept Pharmaceuticals, Inc.DirectorPriorPrior public company board seat .

Board Governance

  • Board leadership and independence: The board is chaired by Mr. Sblendorio (separate from CEO), and the board has determined all directors other than the CEO (Mr. Congleton) are independent under Nasdaq and SEC rules; this includes Mr. Sblendorio .
  • Committee assignments (recent and current): Audit Committee member (2024–Apr 2025); Compensation Committee Chair (Jan 1, 2024 – Feb 13, 2025), after which Dr. Gold became chair; not listed on Nominating & Corporate Governance .
  • Election/class: Class II director up for election at the 2025 annual meeting for a three-year term ending at the 2028 annual meeting .
  • Attendance: The board met six times in 2024; each director (including Sblendorio) attended at least 75% of board and committee meetings on which they served; Audit met 5x, Compensation 5x, Nominating & Corporate Governance 3x .
  • Annual meeting attendance: No director attended the 2024 annual meeting of stockholders (company has no formal policy requiring attendance) — a potential engagement flag .

Committee Roles (timeline)

CommitteeRolePeriodNotes
AuditMemberMay 22, 2024 – Apr 9, 2025Audit Committee member and signatory on the committee’s report .
CompensationChairJan 1, 2024 – Feb 13, 2025Reconstituted on Feb 13, 2025; Dr. Gold named chair thereafter .

Fixed Compensation

  • 2024 cash fees earned: $54,574 (director retainer and applicable committee/leadership retainers) .

Director Cash Retainer Program (structure)

Item2024 Amount (pre-1/1/2025)2025 Amount (effective 1/1/2025)
Base annual retainer (non-employee director)$40,000$40,000
Additional retainer – Chairman of the Board / Lead Independent Director$30,000$32,500
Committee Chair – Audit$15,000$20,000
Committee Chair – Compensation$10,000$15,000
Committee Chair – Nominating & Corporate Governance$8,000$10,000
Committee Member – Audit$7,500$10,000
Committee Member – Compensation$5,000$7,500
Committee Member – Nominating & Corporate Governance$4,000$5,000

Note: No per-meeting fees; reasonable out-of-pocket expenses reimbursed .

Performance Compensation

  • 2024 equity value granted: $197,314 (grant-date fair value of director stock options) .
  • Program mechanics (options only for directors; no PSUs/RSUs disclosed):
    • Initial Grant: 44,000 options (2024 program) or 65,800 options (effective 1/1/2025); vests in substantially equal monthly installments over three years .
    • Annual Grant: 22,000 options (2024) or 32,900 options (effective 1/1/2025) at each annual meeting; vests monthly over 12 months (any remaining unvested portion accelerates at the next annual meeting if held before one year) .
    • Exercise price: Fair market value on grant date; acceleration upon not being renominated/re-elected, death/disability, and upon change in control as defined under the 2023 Plan .

Director Equity Award Terms (structure)

Award TypeGrant SizeVestingExercise PriceAcceleration/Other Terms
Initial Grant (2024 policy)44,000 optionsMonthly over 3 yearsFMV on grant dateAccelerates if not renominated/not re-elected, death/disability, change in control .
Initial Grant (effective 1/1/2025)65,800 optionsMonthly over 3 yearsFMV on grant dateSame as above .
Annual Grant (2024 policy)22,000 optionsMonthly over 12 months (remaining unvested vests at next AGM if <12 months)FMV on grant dateChange in control acceleration and other terms as above .
Annual Grant (effective 1/1/2025)32,900 optionsMonthly over 12 months (AGM catch-up)FMV on grant dateSame as above .

Other Directorships & Interlocks

CategoryDetail
Current public boardsAmicus Therapeutics; Nanoscope Therapeutics .
Prior public boardsIntercept Pharmaceuticals .
Board composition contextBoard includes representatives of significant holders (e.g., RA Capital’s Dr. DiRocco; Samsara’s Dr. Akkaraju; Catalys Pacific’s Dr. Slingsby), reflecting concentrated ownership influence (RA Capital ~9.99%, Samsara ~8.75%, Catalys Pacific ~13.81%) .

Expertise & Qualifications

  • Finance and operating leadership (former CEO, President/CFO, CFO), M&A exits (IVERIC sale to Astellas; Eyetech sale to OSI), and capital markets experience; formal business education (B.B.A., M.B.A.) and Harvard AMP .
  • Committee suitability: Board determined him independent; Audit Committee members (including Sblendorio) meet SEC/Nasdaq financial literacy requirements; audit committee financial expert designation sits with the chair (Karydas) .

Equity Ownership

HolderBeneficial Ownership (shares)% of OutstandingAs-of DateNotes
Glenn P. Sblendorio54,669<1%March 25, 2025Company prohibits pledging/hedging; directors/officers subject to insider trading policy .
Options Outstanding (Director)As-of DateNotes
66,000 optionsDec 31, 2024“Each designated director” held options to purchase 66,000 shares at year-end 2024 (exceptions noted for others; Sblendorio not an exception) .

Governance Assessment

  • Strengths:

    • Independent Chairman separate from CEO, with board-determined independence under Nasdaq/SEC rules; separation enhances oversight .
    • Active committee roles (Audit member; Compensation Chair during 2024) and participation levels meeting board/committee attendance thresholds (≥75%) in 2024 .
    • Director equity is fully at-risk via stock options, aligning with shareholder outcomes; grant sizing increased for 2025, reinforcing equity-based alignment .
  • Watch items / RED FLAGS:

    • No directors attended the 2024 annual meeting (lack of ASM attendance can signal weaker direct shareholder engagement) .
    • Change-in-control and “not renominated/not re-elected” vesting acceleration for director options reduces forfeiture risk; while standard in biotech, it modestly dampens pay-for-performance rigor for directors .
    • Concentrated ownership and board presence from significant investors (RA Capital, Samsara, Catalys) can create perception of investor influence; however, Sblendorio himself is independent .
  • Related-party/Conflicts:

    • The proxy’s related-person transactions section highlights financings and historical agreements with large shareholders, but does not disclose any related-person transactions involving Mr. Sblendorio individually .
    • Section 16(a) compliance: no delinquency noted for Mr. Sblendorio in 2024 (exceptions listed pertained to other insiders) .

Director Compensation – 2024 Actuals (Sblendorio)

YearFees Earned or Paid in Cash ($)Option Awards ($, grant-date FV)Total ($)
202454,574197,314251,888

Insider Trading/Compliance (proxy disclosure)

ItemDisclosure
Section 16(a) filing status (2024)No delinquency noted for Mr. Sblendorio; exceptions listed related to other individuals .

Additional Policies

  • Prohibitions: Directors and officers are prohibited from pledging company stock as collateral, hedging transactions (collars, swaps, exchange funds), margin purchases, short sales, and derivatives in company securities .
  • Indemnification/D&O: Company provides director indemnification agreements and maintains D&O insurance coverage .