Dominic Marasco
About Dominic Marasco
Dominic Marasco, R.Ph., age 52, serves as President, Endocrine Business Unit at MannKind, appointed in January 2025 . He holds a B.S. from Philadelphia College of Pharmacy and completed Harvard Business School’s Advanced Management Program, with a career spanning commercial leadership across biopharma and services (Amgen, Sandoz/Novartis, Syneos Health, BioAgilytix, Envision Pharma) . Company performance entering his tenure: 2024 total revenue $285.5 million and net income $27.6 million; cumulative TSR (fixed $100 from 2019) reached 498.45 through 2024 . MannKind’s endocrine portfolio (Afrezza and V-Go) and UT collaboration (Tyvaso DPI) are core value drivers referenced in executive compensation framing .
Past Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| Envision Pharma Group | Executive President, Chief Commercial Officer; led technology and AI business units and all commercial operations | Feb 2023–Aug 2024 | Led commercialization capabilities and technology/AI units |
| BioAgilytix Labs, Inc. | Chief Commercial Officer | Dec 2019–Dec 2022 | Drove global bioanalytical commercial operations |
| Syneos Health | EVP, Global Business Development, Commercial Group | Feb 2018–Dec 2019 | Led global BD for commercial services |
| Amgen | Head of U.S. Sales, Neuroscience BU; previously Global Commercial Head, Biosimilars | Not disclosed | Led U.S. sales and global biosimilars commercialization |
| Sandoz Biopharmaceuticals (Novartis) | Commercial leadership roles | Not disclosed | Biopharma commercial leadership |
| Quintiles (now IQVIA) | Commercial roles | Not disclosed | CRO/commercial strategy roles |
| Eli Lilly | Sales (after pharmacy practice) | Not disclosed | Early commercial foundation |
External Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| Philadelphia College of Pharmacy | B.S. in Pharmacy | Not applicable | Foundational clinical/technical training |
| Harvard Business School | Advanced Management Program | Not applicable | Senior leadership development |
Fixed Compensation
- Specific 2025 base salary/bonus for Mr. Marasco is not disclosed in the 2025 proxy or 8-Ks; he is not a named executive officer for 2024 .
- Company policy: STI target opportunity is 80% of base for CEO and 50% for other executive officers; 2024 corporate STI funding achieved 125% of target (paid April 2025) .
- Executive stock ownership guidelines: CEO 4× base salary; Executive Vice Presidents 2×; Senior VPs/Vice Presidents on ELT 1×; all execs subject to five-year compliance windows and sale restrictions if not compliant .
Performance Compensation
- Long-term incentives for executives emphasize PSUs (≈55% of LTI) with three-year relative TSR vs. Russell 3000 Pharma & Biotech, and time-based RSUs (≈45% of LTI) . PSU payout schedule: 0% <25th percentile, 50% at 25th, 100% at 50th, 200% at 75th, 300% at ≥90th (interpolated) with July 2027 cliff vesting for 2024 grant cycle; time-based RSUs vest 25% annually (July 2025–July 2028) .
- 2024 STI corporate scorecard (funding basis for executive bonuses paid in 2025), illustrating pay-for-performance mechanics:
| Metric | Target Weight | Assessment Method | Result (as % of total STI) |
|---|---|---|---|
| Deliver on Tyvaso DPI production | 30% | Quantitative production and qualitative capacity expansion | 57.5% |
| Drive endocrinology business | 30% | Quantitative financials and qualitative clinical milestones | 35.0% |
| Advance pipeline opportunities | 30% | Quantitative development milestones | 21.5% |
| Finance/Quality | 10% | Qualitative | 11.0% |
| Overall STI funding | — | — | 125.0% |
- Clawback (Dodd-Frank compliant) applies to incentive compensation tied to financial reporting measures, including stock price and TSR, for executive officers for awards received on/after Oct 2, 2023 .
Equity Ownership & Alignment
- Beneficial ownership for Mr. Marasco is not separately disclosed in the 2025 proxy’s security ownership table; as of March 20, 2025, all current executive officers and directors as a group beneficially owned 8,337,915 shares (2.7%) .
- Hedging/pledging of company stock is prohibited for directors, officers, employees, and household members (short sales, derivatives, margin purchases, loans, options, pledging, or any speculative transactions) .
- Executive stock ownership guidelines in effect (see Fixed Compensation); the proxy states executive officers are currently in compliance with the guidelines, noting guidelines and enforcement mechanisms .
Employment Terms
- Appointment: President, Endocrine Business Unit since January 2025 .
- Change-of-control framework: MannKind maintains change-of-control agreements providing 18 months of base salary continuation, 150% of average annual bonus, continued benefits (up to 18 months), and full vesting of equity upon qualifying separation post-CoC, subject to release; cause/good reason definitions include material duty diminutions, relocation >50 miles, non-renewal, material violations, etc. .
- Coverage statement: MannKind indicated change-of-control agreements with executive officers in 2024 disclosures; 2025 disclosures detail NEO terms and mechanics (Mr. Marasco is not listed as a 2024 NEO) .
- Severance: A specific individual severance agreement is disclosed only for the General Counsel (Thomson); other executives rely on change-of-control agreements for qualifying events .
Performance & Track Record
- Senior commercial operator with U.S. sales leadership (Amgen Neuroscience) and global commercialization (Amgen Biosimilars) background; built BD/commercial capabilities at Syneos; scaled commercial operations and technology/AI at Envision; ran global CCO roles at BioAgilytix .
- Business unit relevance: Endocrine portfolio (Afrezza and V-Go) is a core corporate objective within STI metrics; Tyvaso DPI manufacturing/royalty collaboration provides substantial revenues at the enterprise level .
- Company financial baseline at transition: 2024 revenue $285.5 million; net income $27.6 million; cumulative TSR to 2024 at 498.45 .
Compensation Committee Analysis (Context)
- Peer group (12 companies) used for benchmarking in 2024: ADMA, IRWD, ANIK, KPTI, BCRX, MGNX, DCPH, MIRM, DVAX, RIGL, INSM, VNDA .
- Governance practices: Independent compensation committee; use of Mercer LLC; annual say-on-pay (support ~90% in 2023–2024); prohibition on speculative trading; pay-versus-performance disclosure .
Investment Implications
- Alignment: Prohibition on hedging/pledging reduces misalignment and forced selling risk; executive ownership guidelines and multi-year PSUs tied to relative TSR strengthen long-term incentives .
- Retention: PSU cliff vesting in July 2027 across the executive cohort creates retention hooks; time-based RSUs vest annually (2025–2028), reinforcing continuity heading into Mr. Marasco’s leadership of the Endocrine BU .
- Trading signals: Company policy restricts speculative transactions; watch corporate windows around annual RSU vest dates and PSU outcomes for potential Form 4 activity among executives; Marasco-specific grants/ownership were not disclosed, limiting precision on his personal selling pressure .
- Execution risk: Endocrine BU objectives are central to STI funding and corporate outcomes; Mr. Marasco’s prior commercialization experience is directly relevant to Afrezza/V-Go growth drivers embedded in the STI scorecard .
- Pay-for-performance: Relative TSR-centric PSUs and clear STI metrics indicate high at-risk pay; investors should monitor TSR rank versus Russell 3000 Pharma & Biotech to anticipate PSU payout sensitivity (0–300%) .