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Dominic Marasco

President, Endocrine Business Unit at MANNKINDMANNKIND
Executive

About Dominic Marasco

Dominic Marasco, R.Ph., age 52, serves as President, Endocrine Business Unit at MannKind, appointed in January 2025 . He holds a B.S. from Philadelphia College of Pharmacy and completed Harvard Business School’s Advanced Management Program, with a career spanning commercial leadership across biopharma and services (Amgen, Sandoz/Novartis, Syneos Health, BioAgilytix, Envision Pharma) . Company performance entering his tenure: 2024 total revenue $285.5 million and net income $27.6 million; cumulative TSR (fixed $100 from 2019) reached 498.45 through 2024 . MannKind’s endocrine portfolio (Afrezza and V-Go) and UT collaboration (Tyvaso DPI) are core value drivers referenced in executive compensation framing .

Past Roles

OrganizationRoleYearsStrategic Impact
Envision Pharma GroupExecutive President, Chief Commercial Officer; led technology and AI business units and all commercial operationsFeb 2023–Aug 2024Led commercialization capabilities and technology/AI units
BioAgilytix Labs, Inc.Chief Commercial OfficerDec 2019–Dec 2022Drove global bioanalytical commercial operations
Syneos HealthEVP, Global Business Development, Commercial GroupFeb 2018–Dec 2019Led global BD for commercial services
AmgenHead of U.S. Sales, Neuroscience BU; previously Global Commercial Head, BiosimilarsNot disclosedLed U.S. sales and global biosimilars commercialization
Sandoz Biopharmaceuticals (Novartis)Commercial leadership rolesNot disclosedBiopharma commercial leadership
Quintiles (now IQVIA)Commercial rolesNot disclosedCRO/commercial strategy roles
Eli LillySales (after pharmacy practice)Not disclosedEarly commercial foundation

External Roles

OrganizationRoleYearsStrategic Impact
Philadelphia College of PharmacyB.S. in PharmacyNot applicableFoundational clinical/technical training
Harvard Business SchoolAdvanced Management ProgramNot applicableSenior leadership development

Fixed Compensation

  • Specific 2025 base salary/bonus for Mr. Marasco is not disclosed in the 2025 proxy or 8-Ks; he is not a named executive officer for 2024 .
  • Company policy: STI target opportunity is 80% of base for CEO and 50% for other executive officers; 2024 corporate STI funding achieved 125% of target (paid April 2025) .
  • Executive stock ownership guidelines: CEO 4× base salary; Executive Vice Presidents 2×; Senior VPs/Vice Presidents on ELT 1×; all execs subject to five-year compliance windows and sale restrictions if not compliant .

Performance Compensation

  • Long-term incentives for executives emphasize PSUs (≈55% of LTI) with three-year relative TSR vs. Russell 3000 Pharma & Biotech, and time-based RSUs (≈45% of LTI) . PSU payout schedule: 0% <25th percentile, 50% at 25th, 100% at 50th, 200% at 75th, 300% at ≥90th (interpolated) with July 2027 cliff vesting for 2024 grant cycle; time-based RSUs vest 25% annually (July 2025–July 2028) .
  • 2024 STI corporate scorecard (funding basis for executive bonuses paid in 2025), illustrating pay-for-performance mechanics:
MetricTarget WeightAssessment MethodResult (as % of total STI)
Deliver on Tyvaso DPI production30%Quantitative production and qualitative capacity expansion57.5%
Drive endocrinology business30%Quantitative financials and qualitative clinical milestones35.0%
Advance pipeline opportunities30%Quantitative development milestones21.5%
Finance/Quality10%Qualitative11.0%
Overall STI funding125.0%
  • Clawback (Dodd-Frank compliant) applies to incentive compensation tied to financial reporting measures, including stock price and TSR, for executive officers for awards received on/after Oct 2, 2023 .

Equity Ownership & Alignment

  • Beneficial ownership for Mr. Marasco is not separately disclosed in the 2025 proxy’s security ownership table; as of March 20, 2025, all current executive officers and directors as a group beneficially owned 8,337,915 shares (2.7%) .
  • Hedging/pledging of company stock is prohibited for directors, officers, employees, and household members (short sales, derivatives, margin purchases, loans, options, pledging, or any speculative transactions) .
  • Executive stock ownership guidelines in effect (see Fixed Compensation); the proxy states executive officers are currently in compliance with the guidelines, noting guidelines and enforcement mechanisms .

Employment Terms

  • Appointment: President, Endocrine Business Unit since January 2025 .
  • Change-of-control framework: MannKind maintains change-of-control agreements providing 18 months of base salary continuation, 150% of average annual bonus, continued benefits (up to 18 months), and full vesting of equity upon qualifying separation post-CoC, subject to release; cause/good reason definitions include material duty diminutions, relocation >50 miles, non-renewal, material violations, etc. .
  • Coverage statement: MannKind indicated change-of-control agreements with executive officers in 2024 disclosures; 2025 disclosures detail NEO terms and mechanics (Mr. Marasco is not listed as a 2024 NEO) .
  • Severance: A specific individual severance agreement is disclosed only for the General Counsel (Thomson); other executives rely on change-of-control agreements for qualifying events .

Performance & Track Record

  • Senior commercial operator with U.S. sales leadership (Amgen Neuroscience) and global commercialization (Amgen Biosimilars) background; built BD/commercial capabilities at Syneos; scaled commercial operations and technology/AI at Envision; ran global CCO roles at BioAgilytix .
  • Business unit relevance: Endocrine portfolio (Afrezza and V-Go) is a core corporate objective within STI metrics; Tyvaso DPI manufacturing/royalty collaboration provides substantial revenues at the enterprise level .
  • Company financial baseline at transition: 2024 revenue $285.5 million; net income $27.6 million; cumulative TSR to 2024 at 498.45 .

Compensation Committee Analysis (Context)

  • Peer group (12 companies) used for benchmarking in 2024: ADMA, IRWD, ANIK, KPTI, BCRX, MGNX, DCPH, MIRM, DVAX, RIGL, INSM, VNDA .
  • Governance practices: Independent compensation committee; use of Mercer LLC; annual say-on-pay (support ~90% in 2023–2024); prohibition on speculative trading; pay-versus-performance disclosure .

Investment Implications

  • Alignment: Prohibition on hedging/pledging reduces misalignment and forced selling risk; executive ownership guidelines and multi-year PSUs tied to relative TSR strengthen long-term incentives .
  • Retention: PSU cliff vesting in July 2027 across the executive cohort creates retention hooks; time-based RSUs vest annually (2025–2028), reinforcing continuity heading into Mr. Marasco’s leadership of the Endocrine BU .
  • Trading signals: Company policy restricts speculative transactions; watch corporate windows around annual RSU vest dates and PSU outcomes for potential Form 4 activity among executives; Marasco-specific grants/ownership were not disclosed, limiting precision on his personal selling pressure .
  • Execution risk: Endocrine BU objectives are central to STI funding and corporate outcomes; Mr. Marasco’s prior commercialization experience is directly relevant to Afrezza/V-Go growth drivers embedded in the STI scorecard .
  • Pay-for-performance: Relative TSR-centric PSUs and clear STI metrics indicate high at-risk pay; investors should monitor TSR rank versus Russell 3000 Pharma & Biotech to anticipate PSU payout sensitivity (0–300%) .