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James Shannon

Chair of the Board at MANNKINDMANNKIND
Board

About James S. Shannon

James S. Shannon, M.D., MRCP (UK), age 68, is Chair of the Board and a member of the Compensation Committee at MannKind; he rejoined the board in May 2015 after an earlier term from February 2010 to April 2012 and was appointed Chair in December 2020 . He is independent under Nasdaq standards (the board affirmed all directors except Messrs. Castagna and Binder are independent) . Dr. Shannon trained in medicine and cardiology, earned undergraduate and postgraduate degrees from Queen’s University Belfast, and is a Member of the Royal College of Physicians (UK) .

Past Roles

OrganizationRoleTenureCommittees/Impact
GSK plcChief Medical OfficerMay 2012 – Apr 2015 Senior clinical leadership; global medical governance
Novartis AGGlobal Head, Pharma Development2005 – 2008 Led global development; prior roles included Global Head Clinical Dev & Medical Affairs (1999–2005) and portfolio/program leadership
Sandoz (pre-Novartis)Head, Drug Regulatory Affairs; led R&D integration post-merger1994 – late 1990s Oversaw creation of Novartis R&D; cardiovascular strategy team
Cerimon PharmaceuticalsInterim CEO & PresidentJan 2009 – Apr 2010 Operational turnaround/leadership
Sterling Winthrop Inc.Senior VP, Clinical Development (progressive R&D roles)Joined 1987 Clinical development leadership in EU/US

External Roles

OrganizationRoleTenure
Kyowa Kirin (NA), Inc.ChairmanSince Jul 2019
ProQR Therapeutics NVChairmanSince May 2024
Leyden LabsDirectorSince Sep 2020
Xilio TherapeuticsDirectorSince Jun 2024
Horizon TherapeuticsDirectorAug 2017 – Oct 2023
Immodulon Therapeutics LimitedDirectorJul 2015 – Dec 2021
Biotie; Circassia; Crucell; EndocyteDirector (various)2008–2012 period

Board Governance

  • Roles: Chair of the Board; member, Compensation Committee (Comp Committee comprised of Hooper—Chair, Kay, Shannon) .
  • Independence: Independent; board separation of Chair and CEO is the stated policy and currently implemented (Shannon as Chair; Castagna as CEO) .
  • Attendance: Board met nine times in 2024; each director attended at least 75% of board/committee meetings; all directors attended the 2024 Annual Meeting .
  • Executive sessions: Independent directors hold regular executive sessions .
  • Committee activity: Audit Committee met eight times; Comp Committee met five times; Nominating & Corporate Governance Committee met four times in 2024 .
  • Risk oversight: Board oversees strategy/risk; Audit Committee covers enterprise risk and cybersecurity; Compensation Committee monitors incentive risk .

Fixed Compensation

ComponentProgram DetailShannon FY2024 Cash
Annual retainer$50,000 for non-employee directors
Independent Chair premium$50,000
Committee feesCompensation Committee member: $7,500; Chair: $20,000; Audit Committee member: $10,000; Chair: $25,000; Nominating member: $5,000; Chair: $10,000
Meeting feesNone (no per-meeting fees)
FY2024 cash paid (actual)$90,000

Notes: Non-employee directors may elect to receive the $50,000 cash retainer in stock; reimbursements available for board meeting expenses .

Performance Compensation

Equity AwardGrant MechanicVesting/DeliveryShannon FY2024 Stock Awards (Grant-Date Fair Value)
Annual director RSUTarget set by dividing $250,000 by stock price used for employee equity valuation (not less than last close) RSUs vest immediately; shares delivered upon separation from Board (retirement, removal, death) $155,959
Retainer-in-stock optionRSU equal to 100% of $50,000 retainer based on 20-day avg price (if elected) Vests immediately; delivered at separation Included in total stock awards if elected
  • Options: No new option grants to non-employee directors in 2024; Shannon had 44,505 options outstanding as of 12/31/2024 .
  • Performance metrics: None disclosed for director equity; RSUs are not tied to performance targets and vest immediately with deferred delivery .

Other Directorships & Interlocks

Potential Interlock/OverlapObservation
Compensation committee interlocksCompany states no interlocks: in 2024, none of MannKind’s executive officers served on another entity’s board or compensation committee where a reciprocal relationship existed .
Related party transactionsNone in 2024; related-person transaction policy requires Audit Committee review/approval; no transactions above $120,000 with directors/officers/family .
Independence reviewBoard annually reviews director independence; all directors except Messrs. Castagna and Binder deemed independent; no disqualifying relationships found .

Expertise & Qualifications

  • Deep drug development and portfolio leadership (Novartis global development leadership; CMO of GSK) bringing scientific and operational expertise to MNKD’s R&D-intensive strategy .
  • Medical credentials (MD; MRCP UK) with clinical leadership background; trained in cardiology; degrees from Queen’s University Belfast .
  • Broad governance footprint across biopharma boards (current Chair roles at Kyowa Kirin NA and ProQR; prior Horizon Therapeutics) .

Equity Ownership

MetricValueNotes
Beneficial ownership (SEC definition)68,963 shares; <1% of outstanding Includes 24,458 common shares + 44,505 vested options
Vested RSUs held for future delivery470,550 shares Delivered upon separation from Board
Options outstanding (non-employee directors)44,505 (Shannon) Legacy grants; no 2024 director options
Hedging/pledgingProhibited by Insider Trading Policy (no derivatives, short sales, pledging) Applies to directors/officers/employees
Stock ownership guideline3x annual retainer; 5-year grace period; both vested/unvested awards count All non-employee directors in compliance as of 12/31/2024

Governance Assessment

  • Board leadership and independence: Separation of Chair/CEO, regular executive sessions, and committee independence support effective oversight; Shannon’s role as independent Chair is aligned with stronger oversight norms .
  • Engagement and attendance: Board met nine times; all directors attended the 2024 Annual Meeting; minimum 75% attendance achieved by each director, signaling engagement .
  • Compensation governance: Comp Committee uses Mercer LLC; independence evaluation found no conflicts; committee met five times, with pay-for-performance philosophy and clawback policy implemented at the executive level .
  • Shareholder sentiment: Say-on-pay support has been strong in recent years (2021–2024 at 89–90%), indicating constructive investor feedback loops to the compensation and governance approach .
  • Conflicts/related-party: No related party transactions in 2024; independence determinations found no disqualifying relationships; hedging/pledging prohibitions reduce alignment risks .

Director Compensation (FY2024)

ComponentAmount ($)
Fees Earned or Paid in Cash90,000
Stock Awards (Grant-Date Fair Value)155,959
Total245,959

Footnotes: No option grants to non-employee directors in 2024; Shannon had 44,505 options outstanding; directors held vested RSUs for future share delivery (Shannon: 470,550) .

Say-on-Pay & Shareholder Feedback

YearSay-on-Pay Support (%)
201967%
202061%
202189%
202288%
202390%
202490%

Compensation Committee Analysis

  • Composition and independence: Hooper (Chair), Kay, Shannon—each independent under Nasdaq rules .
  • Consultant: Authority to engage independent advisors; Mercer LLC currently engaged; independence assessment concluded no conflict of interest .
  • Activities: Five meetings in 2024; oversees executive pay policies, approves goals, administers equity plans, and reviews severance/change-of-control arrangements .

RED FLAGS

  • None disclosed: No 2024 related-party transactions; no hedging/pledging; strong say-on-pay outcomes; independent Chair and committees .
  • Monitoring point: Multiple external board chair/director roles may pose time-commitment considerations; the board’s annual independence review found no disqualifying relationships .
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