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Julie Jordan

Chief Medical Officer at Neurogene
Executive

About Julie Jordan

Julie Jordan, M.D., is Chief Medical Officer at Neurogene Inc. (NGNE) since January 16, 2024; age 53 as of April 25, 2025. She holds an A.B. in Biology from Harvard College and an M.D. from Harvard Medical School, and completed an internal medicine residency at Massachusetts General Hospital (Harvard Medical School) . Neurogene is a clinical-stage biotechnology company; corporate TSR per pay-versus-performance shows a $100 investment valued at $11 (2022), $20 (2023), and $24 (2024), with net losses of $(60,692)k, $(36,317)k, and $(75,144)k respectively . NGNE’s 2025 10-Q confirms single-segment clinical operations and continued net losses, underscoring execution risk typical of development-stage biotech .

Past Roles

OrganizationRoleYearsStrategic Impact
Homology Medicines, Inc.Chief Medical OfficerMar 2023 – Aug 2023Led clinical development/operations, regulatory interactions, supported translational research across gene therapy/editing pipeline
Homology Medicines, Inc.SVP, Head of Clinical Development & OperationsFeb 2022 – Mar 2023Led clinical development/operations
Homology Medicines, Inc.VP, Clinical DevelopmentMay 2021 – Feb 2022Advanced early clinical programs
Cerevel Therapeutics, LLCSenior Director, Global Clinical DevelopmentAug 2019 – Apr 2021Led clinical development/operations in neurology
Avanir Pharmaceuticals, Inc.Executive Director, Global Clinical DevelopmentMar 2019 – Jul 2019Oversaw global clinical development
Avanir Pharmaceuticals, Inc.Senior Director, Global Clinical DevelopmentApr 2017 – Feb 2019Led clinical development/operations

External Roles

InstitutionRoleYearsNotes
Harvard Medical School / Massachusetts General HospitalClinical Instructor of Medicine; PhysicianNot disclosedTreated patients at MGH; academic clinical role prior to industry

Fixed Compensation

Metric2024
Base Salary ($)460,000
Target Bonus (%)40%
Target Bonus ($)192,000
Actual Bonus Paid ($)184,636 (prorated for start date)
All Other Compensation ($)6,400 (401(k) match)

Performance Compensation

Annual Cash Bonus

ComponentTargetActualMetric DetailsPayout Timing
Annual Incentive (Cash)40% of base ($192,000) $184,636 (prorated for 2024 start) Board-discretionary based on individual and company performance goals (specific metrics not disclosed) Paid early following fiscal year

Stock Options

Award TypeGrant DateUnitsExercise PriceExpirationVestingStatus at 12/31/2024
Non-qualified Stock Options1/16/202475,000 $32.30 1/16/2034 25% on first anniversary (1/16/2025), then monthly over 36 months Exercisable: 0; Unexercisable: 75,000

Equity award grant practices: the Compensation Committee adopted timing guidelines in Sept 2024 to avoid grants near material nonpublic information and outside trading windows .

Equity Ownership & Alignment

ItemValue
Total Beneficial Ownership (as of Apr 16, 2025)24,999 shares (consists of options exercisable within 60 days)
Ownership % of Shares Outstanding“*” (below 1%)
Options Outstanding (12/31/2024)75,000 unexercisable; 0 exercisable
Stock Ownership Guidelines (executives)Not disclosed in proxy
Hedging/Derivatives PolicyCompany prohibits short-term trading, short sales, publicly traded options on Company stock, and hedging transactions
Pledging of Company StockNot disclosed

Company reserved shares and pre-funded warrants present potential dilution: total common stock reserved for issuance, options, RSUs/PSUs, and pre-funded warrants are detailed in Q3 2025 10-Q .

Employment Terms

TermDetails
Employment Start DateJanuary 16, 2024 (offer letter effective)
Current RoleChief Medical Officer
Contract FormExecutive Employment Agreement dated April 1, 2024
Base Salary (Agreement)$480,000
Target Bonus (Agreement)40% of base salary
Equity EligibilityAnnual equity incentives per Board discretion
ClawbackAwards subject to Company clawback policy per Exchange Act Rule 10D-1 and any adopted policy
Non-Compete / Non-SolicitNot disclosed
Severance (Non-Change-in-Control)Lump sum equal to 9 months base salary; earned prior-year bonus (if any) unpaid at termination; pro-rata current-year bonus; up to 9 months healthcare premiums (subject to release and covenants)
Change-in-Control (Double Trigger: 3 months before to 12 months after)Lump sum equal to 1x base + 1x target bonus; earned prior-year bonus paid; up to 12 months healthcare premiums; full acceleration of all equity awards (subject to release)
Definitions“Cause,” “Good Reason,” and “Change in Control” defined in agreement (material diminution, salary reduction, >50-mile relocation; CIC includes >50% ownership change, board majority change, merger, liquidation, asset sale)

Performance & Track Record

Metric202220232024
Value of $100 Investment (TSR) ($)11 20 24
Net Income (Loss) ($000s)(60,692) (36,317) (75,144)

Operating model: single reportable segment; CODMs are CEO and President/CFO; R&D/G&A expense drivers detailed in Q3 2025 10-Q .

Compensation Committee, Say-on-Pay & Governance Signals

  • Compensation Committee: Chair Rohan Palekar; members Sarah B. Noonberg. Consultant Aon engaged in 2024 .
  • Say-on-Pay 2025: For 7,721,866; Against 3,174,484; Abstain 104,448; Broker Non-Votes 480,734 .
  • Equity Plan mechanics: 2023 Equity Plan permits option/SAR repricing and exchanges without shareholder approval; CIC acceleration standard; evergreen share increases amended to include pre-funded warrants and preferred conversions starting 2026 .

Investment Implications

  • Pay-for-performance alignment: 2024 pay mix is equity-heavy (options grant fair value $1.809m vs salary $460k), with cash bonus tied to Board-set performance goals; specific quantitative metrics are not disclosed, limiting transparency on pay-performance linkage .
  • Retention and selling pressure: Four-year option vesting (25% cliff after one year; monthly thereafter) creates retention incentives but may introduce periodic selling pressure around vest dates; full acceleration under double-trigger CIC increases potential deal-related overhang .
  • Alignment and governance: Beneficial ownership is modest (24,999 options exercisable within 60 days as of record date), reducing “skin-in-the-game”; anti-hedging policy mitigates misalignment risk, but plan-level repricing/exchange authority is a governance red flag to monitor .
  • Performance backdrop: Persistent net losses and low TSR reflect development-stage risk; bonus discretion plus option-centric equity suggests emphasis on execution milestones rather than near-term financials—watch clinical readouts (e.g., NGN-401 milestones referenced in PSUs for other NEOs) as potential triggers influencing compensation outcomes and stock reaction .