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Paul L. Berns

Paul L. Berns

Chief Executive Officer at Neumora Therapeutics
CEO
Executive
Board

About Paul L. Berns

Paul L. Berns, 58, is Co‑Founder of Neumora Therapeutics and has served as Chief Executive Officer and Chairman since February 2025; previously Executive Chairman (July 2023–Feb 2025), CEO (Nov 2019–July 2023), and Chairman (Jan 2020–July 2023). He holds a B.S. in Economics from the University of Wisconsin and is a Managing Director at ARCH Venture Partners (joined as Venture Partner in Aug 2018) . The Board currently combines the CEO and Chair roles under Berns and deems the structure appropriate; all other directors are independent under Nasdaq rules and meet in regular executive sessions . 2025 context: following the KOASTAL‑1 study miss, the Board proposed an option repricing to restore retention incentives, highlighting execution risk/volatility in the near term .

Past Roles

OrganizationRoleYearsStrategic Impact
Anacor PharmaceuticalsPresident, CEO & ChairmanCompany acquired by Pfizer in 2016
Allos TherapeuticsPresident & CEOCompany acquired by Spectrum Pharmaceuticals
Bone Care InternationalPresident & CEOCompany acquired by Genzyme Corporation
Abbott LaboratoriesVP & GM, Immunology/Oncology/Pain BUSenior operating leadership at large-cap pharma
BASF Pharmaceuticals/KnollVice President, MarketingBusiness acquired by Abbott in 2001
Bristol‑Myers SquibbVarious senior rolesEarly senior management experience

External Roles

OrganizationCapacityYearsNotes
ARCH Venture PartnersManaging Director (joined as Venture Partner Aug 2018)2018–presentVenture leadership; potential related-party considerations via ARCH holdings
Metsera, Inc.Director; Co‑FounderPublic company board
UNITY BiotechnologyDirectorPublic company board
Various private companiesDirectorMultiple private boards

Fixed Compensation

Component2024 (Executive Chairman)Notes2025 (CEO/Chair)Notes
Base Salary ($)470,000 2024 base disclosed in SCT and narrative700,000 Per Feb 2025 Executive Employment Agreement
Target Cash Bonus (% of salary)60% Under Executive Chairman Agreement and 2024 bonus program60% Per Executive Employment Agreement
Actual Annual Bonus ($)253,800 Based on 2024 corporate goals (see below)2025 not yet disclosed
All Other Compensation ($)11,130 401(k) match $10,350 + electronics allowance $780 Not disclosed

Performance Compensation

  • 2024 annual bonus framework: For Berns, bonus based 100% on corporate goals; Compensation Committee assessed 2024 corporate goal achievement at 85% and exercised discretion to pay at 90% of target .
  • Equity program emphasizes options and RSUs with time-based vesting; 2025 CEO grant meaningfully increases option leverage at a depressed strike post-2025 drawdown .

2024 Bonus Outcome

MetricWeightingTargetActualPayout
Corporate goals (undisclosed components)100% (Berns) 100%90% of target (committee adjusted) $253,800 paid (SCT)

Key Equity Grants and Vesting

Grant DateAward TypeShares/UnitsExercise PriceVestingExpiration
Feb 14, 2024Stock Options342,500 $18.07 25% on 1st anniversary; monthly thereafter (48 months) Feb 13, 2034 (from OEA table)
Feb 14, 2024RSUs171,250 25% annually over 4 years
July 3, 2023 (grant)Stock Options955,864 (allocated: 338,535 exc.; 617,329 unexc. at 12/31/24) $6.36 25% on July 3, 2024; monthly thereafter June 27, 2033
Feb 1, 2022Stock Options497,049 (352,076 exc.; 144,973 unexc. at 12/31/24) $4.63 25% after 1 year; monthly thereafter Jan 26, 2032
Feb 13, 2025Stock Options2,000,000 $1.69 25% on Feb 13, 2026; monthly thereafter

Note: OEA table shows additional historical option lots; vesting schedules follow standard 4‑year patterns unless noted .

Equity Ownership & Alignment

ItemDetail
Common shares owned (direct)7,675,857; all vested within 60 days of April 10, 2025; 0 subject to repurchase
Options exercisable within 60 days1,067,963
Total beneficial ownership8,743,820 shares; 5.4% of outstanding (based on 161,747,922 shares outstanding)
Hedging/pledgingCompany policy prohibits hedging and pledging, and margin purchases, for all insiders
Ownership guidelinesNot disclosed in the proxy; not found

Employment Terms

  • Executive Employment Agreement (Feb 2025): Base $700,000; target bonus 60%; granted 2,000,000 options at $1.69 with 4‑year vesting (25% after 1 year, then monthly) .
  • Severance (non‑CIC): If terminated without cause or resigns for good reason outside the CIC window, eligible for 12 months base salary, target bonus, and up to 12 months healthcare/Cobra .
  • Severance (CIC double‑trigger): If such termination occurs within the window from 3 months prior to through 18 months after a change in control, eligible for 2x base salary, 2x target bonus, up to 2 years healthcare/Cobra, and full acceleration of all equity awards; subject to release .
  • Prior Executive Chairman Agreement (July 2023): Base $450,000; 60% target bonus; 955,864 options at $6.36; single‑trigger full acceleration upon change in control under that prior agreement (superseded in 2025) .

Board Governance

  • Board class/tenure: Berns is a Class III director; term expires at the 2026 annual meeting; director since 2020 .
  • Independence: All directors except Berns are independent under Nasdaq rules; Audit, Compensation, and Nominating/Governance committees are fully independent .
  • Committees: Compensation Committee members are Kristina Burow (Chair), Matthew Fust, and Alaa Halawa; uses independent consultant Alpine (no conflicts found) .
  • Attendance: In 2024, Board met 5 times; each director attended at least 75% of Board/committee meetings .
  • CEO/Chair dual role: Board permits combining roles and currently combines them under Berns; may appoint a Lead Independent Director if needed .

Related‑Party and Special Items

  • ARCH and Amgen: ARCH entities own 19.7% and Amgen owns 21.9% of common stock; ARCH-affiliated director on the Board; Amgen has licensing/collaboration agreements and board designation rights while owning ≥10% .
  • BlackThorn milestone: In Dec 2023, contingent consideration included $601,538 cash to Berns related to pre‑merger equity vested at BlackThorn; ARCH received 1,879,654 shares; settlements generally in cash or stock per agreement .
  • Clawback: SEC/Nasdaq‑compliant clawback adopted Sept 14, 2023 for incentive comp tied to financial reporting measures over the lookback period .
  • Option repricing proposal (2025 AGM): Board seeks approval to reprice certain underwater options after KOASTAL‑1 miss; early exercise or termination before Aug 13, 2026 would reset repriced options to original higher strike, enhancing retention .

Performance & Track Record

  • Neumora events: KOASTAL‑1 primary endpoint miss in 2025 led to significant stock price decline and retention concerns; underpinning the option repricing rationale .
  • Prior value‑creation record: Led three biopharma companies through acquisitions (Anacor→Pfizer, Allos→Spectrum, Bone Care→Genzyme), demonstrating serial M&A outcomes .

Director Compensation (context)

  • Non‑employee director program: $45,000 annual retainer; additional committee fees; equity mix of options and RSUs under Initial ($725k FV) and Annual ($400k FV) grants with standard vesting; March 2025 update sets Initial option at 160,000 shares and Annual option at 80,000 shares; full vest on change in control .
  • 2024 director pay (examples): Total ranged ~$467k–$493k per director; includes RSUs and options valued under ASC 718 .

Compensation Structure Analysis

  • Mix and leverage: 2024 pay for Berns included significant option value ($4.82M) and RSUs ($3.09M), indicating high equity-at‑risk; 2025 CEO grant of 2.0M options at $1.69 further increases upside leverage if execution improves .
  • Shift in terms: Transition from Executive Chairman (single‑trigger CIC acceleration) to CEO (double‑trigger CIC with full acceleration plus 2x salary/bonus) aligns with market norms but increases potential parachute cost .
  • Discretionary adjustments: Committee uplifted 2024 corporate bonus result from 85% to 90%, a modest discretionary positive adjustment .
  • Retention actions: Proposed option repricing is a notable governance flag for some investors but is explicitly framed as a retention tool following program setbacks; features guardrails that revert strike if exercised/terminated before Aug 13, 2026 .

Equity Ownership & Alignment Details

HolderShares Outstanding OwnedOptions Exercisable ≤60 daysTotal BeneficialOwnership %
Paul L. Berns7,675,857 1,067,963 8,743,820 5.4%
Shares outstanding basis161,747,922
  • Footnote: All 7,675,857 Berns shares were vested within 60 days of April 10, 2025; 0 subject to repurchase .

Employment Terms (Severance & CIC) Summary

ScenarioCashBonusHealthcareEquity
Termination without cause / for good reason (outside CIC window)12 months base salary Target bonus Up to 12 months COBRA/reimbursements No automatic acceleration disclosed
Termination within CIC window (3 months pre‑ to 18 months post‑CIC)2x base salary 2x target bonus Up to 2 years COBRA/reimbursements Full acceleration of all equity awards

Investment Implications

  • Alignment and upside: Berns’ 5.4% beneficial stake and large, low‑strike 2025 option grant enhance alignment with equity holders and amplify sensitivity to pipeline/value inflections .
  • Retention and overhang: The Board‑proposed option repricing and sizeable unvested options indicate a strong focus on retention after KOASTAL‑1; however, repricing and potential equity overhang may be governance and dilution concerns for some investors .
  • Selling pressure windows: Time‑based vesting (annual cliffs for RSUs; monthly for options) creates recurring liquidity windows that can coincide with insider trading plans, potentially adding technical pressure around vest dates; the company’s hedging/pledging prohibitions mitigate misalignment risk .
  • Downside protections: Double‑trigger CIC with full acceleration and 2x cash provides robust downside protection for the CEO, which can be retention‑positive but increases parachute exposure in strategic scenarios .
  • Governance: Combined CEO/Chair role is balanced by a fully independent committee structure and regular executive sessions; continued monitoring of independence/lead director usage is warranted given dual role and related‑party dynamics (ARCH/Amgen) .