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John Fesko

President, Chief Business Officer at NateraNatera
Executive

About John Fesko

John Fesko is President, Chief Business Officer at Natera, appointed to the President/CBO role in September 2023 after serving as Chief Business Officer (January 2020–August 2023) and SVP, Business Development (January–December 2019); he joined Natera in February 2014 in business development roles. He is 46, holds an MBA from MIT and a BS in Biochemistry and Economics from the University of Notre Dame, and previously worked at Roche Molecular Systems, Novartis, MPM Capital, and InVivoScribe . Company performance under the 2024 plan featured total revenue of $1,696.9 million (+56.7% YoY), gross margin improvement to 60.3%, and operating cash flow of $86.5 million, driving a 119.1% company performance payout factor .

Past Roles

OrganizationRoleYearsStrategic Impact
NateraPresident, Chief Business OfficerSep 2023–presentExecutive leadership across commercial and corporate development
NateraChief Business OfficerJan 2020–Aug 2023Led business development and commercial strategy
NateraSVP, Business DevelopmentJan–Dec 2019Senior BD leadership
NateraBusiness Development rolesFeb 2014–2018BD roles since joining (exact titles not itemized)

External Roles

OrganizationRoleYearsStrategic Impact
Roche Molecular Systems, Inc.Not disclosedNot disclosedPrior industry experience
Novartis Pharma AGNot disclosedNot disclosedPrior industry experience
MPM CapitalNot disclosedNot disclosedPrior investing role
InVivoScribe, Inc.Not disclosedNot disclosedPrior industry experience

Fixed Compensation

Metric20232024Notes
Base Salary ($)$475,000 $489,250 3% increase effective Jan 1, 2024
Target Bonus (% of Base)Not disclosed50% Weighting: 80% company, 20% individual
Target Bonus ($)Not disclosed$243,436 Prorated change effective Mar 1, 2024
Actual Bonus Paid ($)Not disclosed$285,574 Delivered as fully vested RSUs on Mar 12, 2025; value set using Mar 11, 2025 close

Performance Compensation

Annual Cash Incentive – 2024 Company Metrics

MetricWeighting (%)ThresholdTargetMaximumActualPayout (% of Target)
Revenue55 $1,103.47M $1,298.2M $1,142.93M $1,969.6M 120.0%
Product Gross Margin35 41.0% 51.3% 61.6% 60.3% 117.5%
Operating Cash Flow10 $(126.1)M $(100.9)M $(75.7)M $86.5M 120.0%
Overall Company Factor119.1%

Individual Performance Factor (Fesko)

ExecutiveIndividual Factor WeightAchievementNotes
John Fesko20% 110% Determined by HCC based on accomplishments

2024 Bonus Outcome (Fesko)

ExecutiveTarget Bonus ($)Company Payout ($)Individual Payout ($)Total Actual ($)% of Target
John Fesko$243,436 $232,018 $53,556 $285,574 117.31%

Long-Term Incentives – 2024 Grants (Fesko)

Award TypeGrant DateUnits (#)Target Grant Value ($)VestingPerformance Metric / Scale
PSUsJan 26, 2024 31,352 $2,000,000 3-year performance period2024–2026 cumulative revenue; 95%/100%/105% → 50%/100%/200% payout
RSUsJan 26, 2024 31,352 $2,000,000 4 years; 25% at 12 months, then quarterly Time-based retention

Prior Performance-Based Vesting (selected items impacting 2024–2025)

Award TypeGrant DateVest DateUnits VestedTrigger
PSUAug 12, 2022 Aug 12, 2024 10,000 Cash flow breakeven quarter achieved
PSUOct 22, 2021 Dec 20, 2024 1,675 Business milestone achieved
PSUJun 10, 2022 Jan 16, 2025 10,822 $300M cash burn and $1.1B revenue goals achieved
PSUJan 28, 2022 Jan 16, 2025 13,696 $1.1B annual revenue achieved
PSUJan 27, 2023 Jan 16, 2025 14,899 2-year cumulative revenue goal achieved (40% tranche)

Equity Ownership & Alignment

Beneficial Ownership (as of March 15, 2025)

HolderDirect SharesOptions/RSUs Vesting ≤60 DaysTotal Beneficial% of SO
John Fesko93,476 20,955 114,431 <1%
  • Hedging and pledging of company stock are prohibited for employees and directors; executive stock ownership guidelines are in place (specific multiples not disclosed) .
  • Outstanding unexercised options and unvested RSUs (as of Dec 31, 2024) for Fesko include multiple tranches; selected positions summarized below .

Outstanding Equity Awards (as of Dec 31, 2024)

AwardExercisable (#)Unexercisable (#)Exercise Price ($)Expiration/NotesUnvested RSUs/Equity (#)Market Value ($)
Stock Option1,804 9.29 3/8/2028
Stock Option1,725 15.57 3/7/2029
Stock Option12,283 19.68 3/21/2029
RSU (performance/time mix)See footnotes501 $79,308
RSU4,280 $677,524
RSU7,214 $1,141,976
RSU20,952 $3,316,702
RSU31,352 $4,963,022
RSU13,696 $2,168,077
RSU10,822 $1,713,123
RSU29,798 $4,717,023

Notes (vesting mechanics):

  • 75% of certain RSUs vest upon achieving $1.1B revenue and 25% upon $300M cash burn; both achieved and certified Jan 16, 2025 .
  • Multi-year cumulative revenue PSU tranches exist for 2025–2026 with target counts shown in the table, subject to certification .

2024 Exercises/Vesting (liquidity potential)

MetricSharesValue ($)
Options exercised100 $10,239
RSUs vested44,113 $4,295,525

Employment Terms

Severance Plan (adopted 2024; Participation Agreement executed)

  • Cash severance: 6 months base salary; increases to 12 months if termination within 12 months post change in control (double trigger) .
  • COBRA premiums: Company-paid up to 12 months .
  • Equity acceleration (involuntary termination not in connection with CIC): Time-based awards accelerate by greater of 50% of unvested or forward-vesting as if 12 more months of service; PSUs accelerate proportionally based on actual performance and service fraction with an added 12 months service credit .
  • Equity acceleration (termination within 12 months post CIC): Time-based awards 100% vest; PSUs: revenue milestones use board-approved forecasts; market cap milestones use transaction valuation; other milestones fully vest .
  • Good Reason definition includes material reduction in authority, base salary reduction, or relocation >30 miles without remote option, with notice/cure periods; Cause and CIC definitions per CEO section apply .

Potential Payments (assuming CIC and termination on Dec 31, 2024)

ScenarioCash Severance ($)COBRA ($)Equity Acceleration ($)Total ($)
Involuntary Termination (no CIC)$244,625 $35,027 $21,744,602 $22,024,254
CIC Termination (double trigger)$489,250 $35,027 $25,806,858 $26,331,135
CIC Acceleration Only$8,598,223 $8,598,223

Clawbacks and Other Policies

  • Clawback: Incentive compensation subject to recoupment policy and applicable law .
  • No excise tax gross-ups; no option/SAR repricing without shareholder approval .

Investment Implications

  • Strong pay-for-performance alignment: 2024 annual incentive tied to revenue (55%), product gross margin (35%), and operating cash flow (10), with actual performance exceeding targets (119.1% factor), and bonus delivered as fully vested RSUs—aligning outcomes with shareholder value while creating near-term liquidity for insiders .
  • Retention balanced with performance: 50/50 mix of PSUs and RSUs; PSUs on multi-year cumulative revenue with an aggressive 200% max payout at 105% of target, and time-based RSUs vesting over 4 years—anchoring both execution and retention .
  • Change-in-control economics: Double-trigger cash and equity benefits; performance award treatment under CIC reduces uncertainty (forecast-based revenue determination, transaction valuation for market-cap awards), with substantial equity acceleration potential ($25.8M) signaling meaningful incentive continuity but also investor dilution risk if broadly applied .
  • Ownership and selling pressure: Fesko beneficially owns 114,431 shares (<1% of SO), had 44,113 RSUs vest in 2024, and received March 2025 vested RSUs for bonus—raising potential short-term selling pressure; pledging/hedging prohibited, and ownership guidelines exist (multiples not disclosed) .
  • Governance and shareholder support: Say-on-pay approval at ~94.5% in 2024 indicates broad investor alignment; compensation peer group targets long-term incentive value ~75th percentile—competitive but monitored by independent consultant (Aon) .