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Jason Aryeh

Director at Orchestra BioMed Holdings
Board

About Jason Aryeh

Jason Aryeh (age 56) is an independent Class I director of Orchestra BioMed Holdings (OBIO), serving since January 2023 and chairing the Nominating & Corporate Governance Committee; he previously served as a director of Legacy Orchestra from November 2018 and as a strategic advisor in 2018. He is founder and managing general partner of JALAA Equities, LP (biotech and medical devices) since 1997, and holds a B.A. in economics (honors) from Colgate University .

Past Roles

OrganizationRoleTenureCommittees/Impact
QLT Inc.DirectorJun 2013 – Nov 2016Predecessor to Novelion Therapeutics; board oversight during transition
Novelion Therapeutics Inc.DirectorNov 2016 – Aug 2018Nasdaq-listed biopharma; board oversight
Cystic Fibrosis Foundation TherapeuticsDirector2012 – Feb 2019Non-profit therapeutics board

External Roles

OrganizationExchangeRoleTenureCommittees/Impact
Ligand Pharmaceuticals, Inc. (LGND)NasdaqDirector; Chair, Nominating & Governance; prior Compensation memberSince Sep 2006Governance leadership, oversight
Anebulo Pharmaceuticals (ANEB)NasdaqDirector; Audit Committee memberSince Mar 2021Financial oversight
Rio Grande Renewables, LLCPrivateExecutive Chair (co-founder)Since Mar 2009Strategy, leadership

Board Governance

  • Independence: Board determined Aryeh “independent” under Nasdaq and SEC rules .
  • Committees: Chair, Nominating & Corporate Governance; Member, Compensation Committee (current composition) .
  • Class and term: Class I; current term expires at the 2027 annual meeting .
  • Attendance and engagement: In FY2024, the Board held 7 meetings and each director attended at least 75% of Board and applicable committee meetings; Compensation Committee held 5 meetings and 7 written consents; Nominating & Governance held 2 meetings and 4 written consents; Audit Committee held 5 meetings and 1 written consent .
  • Lead Independent Director: Eric S. Fain, M.D. .
  • Executive sessions and leadership: Committees comprised solely of independent directors; independent directors meet in executive session after regular Board meetings .

Fixed Compensation

Component (2024)Amount ($)Notes
Annual Board Retainer45,000Non-employee director cash retainer
Audit Committee Member Fee10,000Received for 2024 service; policy rate
Nominating & Governance Chair Fee10,000Chair premium
Total Cash Fees (2024)65,000Sum of items above
Option Award (Grant-date fair value)84,999Annual NSO award; policy target $85,000
Stock Award (RSU grant-date fair value)39,997Annual RSU; policy target $40,000
Total 2024 Compensation189,996Cash + equity

Policy details:

  • Annual director cash fees: Board $45,000; Audit Chair $20,000/Members $10,000; Compensation Chair $15,000/Members $7,500; Nominating Chair $10,000/Members $5,000 .
  • Equity: At each annual meeting, NSO (fair value $85,000) and RSU ($40,000), vesting fully on the earlier of one year from grant or next annual meeting; full vesting upon death, disability, or change in control, subject to continued service .

Performance Compensation

  • OBIO’s non-employee director compensation is not performance-based; equity vests time-based per policy (no revenue/EBITDA/TSR metrics disclosed for directors). Annual NSO/RSU grant values and vesting terms per policy above .

Other Directorships & Interlocks

  • No disclosed overlapping directorships between Aryeh and OBIO’s major strategic partner/holder Medtronic; Medtronic holds 15.3% and is AVIM collaborator, requiring ongoing conflict oversight at the Board level .
  • Large holders: RTW Investments (20.1%), Medtronic (15.3%), Perceptive Life Sciences (12.0%) .

Expertise & Qualifications

  • 25+ years investing and board leadership in life sciences; leads JALAA Equities (biotech/med devices) since 1997 .
  • Governance experience: Chair of Nominating & Governance at Ligand; service on Anebulo’s Audit Committee .
  • Education: B.A. in economics (honors), Colgate University .

Equity Ownership

Item (as of Apr 28, 2025 record date)Shares% of Class
Shares held directly74,684 *
Options exercisable within 60 days77,255 *
RSUs settling within 60 days5,376 *
Total beneficial ownership157,315 *

Notes and alignment signals:

  • Anti-hedging/insider trading policy prohibits short sales and requires pre-clearance; trades only during windows or via 10b5-1 plans .
  • As of 12/31/2024, Aryeh held 79,193 stock options and 5,376 RSUs (award inventory disclosure) .
  • Insider alignment via participation in Legacy financing: purchased 53,763 Series D‑2 Preferred shares for $250,000 (June 30, 2022) prior to Business Combination .

Governance Assessment

  • Strengths:
    • Independent director with deep governance experience; chairs Nominating & Governance and sits on Compensation Committee .
    • Documented engagement: Board/committee meeting cadence and ≥75% attendance standard met by all directors in FY2024 .
    • Ownership alignment: meaningful beneficial holdings and recent equity awards; anti-hedging policy in place .
  • Potential risks and monitoring points:
    • Multiple external commitments (Ligand chair, Anebulo audit, Rio Grande Renewables) necessitate ongoing time-commitment assessment; Nominating & Governance oversees performance and composition annually .
    • Investment fund leadership (JALAA Equities) could create potential related-party exposure; OBIO maintains a formal related-person transaction policy under Item 404 with Audit Committee oversight; no related-party transactions involving Aryeh beyond his 2022 investment are disclosed .
    • Strategic concentration: Medtronic’s 15.3% stake and collaboration on AVIM require robust conflict oversight; no interlock with Aryeh disclosed, but Board/committee structures and independence mitigate risk .

RED FLAGS: None explicitly disclosed for Aryeh regarding legal proceedings, pledging, tax gross-ups, or option repricings; monitor for any related-party transactions tied to external roles and for sustained attendance/engagement levels .