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Andrew Phillips

Chairperson of the Board at OnKure Therapeutics
Board

About Andrew Phillips

Andrew Phillips, Ph.D. (age 54) is an independent director and Chairperson of the Board at OnKure Therapeutics (OKUR) since the October 4, 2024 merger; he previously served on Legacy OnKure’s board since March 2021 . He holds a B.Sc. in biochemistry and a Ph.D. in chemistry from the University of Canterbury (NZ) and has deep operating and scientific credentials across biotech, including CEO/President roles, buy-side experience, and academic appointments . As Chair, he leads independent oversight separate from the CEO, consistent with the board’s chosen leadership structure .

Past Roles

OrganizationRoleTenureCommittees/Impact
Aleksia Therapeutics, Inc.President & Chief Executive OfficerSince Aug 2022Executive leadership
Nexo Therapeutics, Inc.President & Chief Executive OfficerSince Aug 2022Executive leadership
Cormorant Asset ManagementManaging DirectorAug 2020–Aug 2022Buy-side investment leadership
Enliven Therapeutics, Inc. (NASDAQ: ELVN)DirectorSince Dec 2020Board oversight
MoonLake Immunotherapeutics, Inc. (NASDAQ: MLTX)DirectorSince Apr 2021Board oversight
Helix Acquisition Corp.Chief Financial OfficerApr 2021–Apr 2022Capital markets/SPAC finance
Blossom Bioscience Ltd.Chief Executive OfficerSince Jun 2021Executive leadership
C4 Therapeutics, Inc. (NASDAQ: CCCC)CEO; President; Chief Scientific OfficerCEO: May 2018–Mar 2020; President: Sep 2016–May 2018; CSO: Jan 2016–May 2018Company building and drug discovery leadership
Broad InstituteSenior Director, Center for Development of TherapeuticsJul 2014–Jan 2016Translational R&D leadership
Yale UniversityProfessor of ChemistryJun 2010–Jan 2015Academic leadership
University of ColoradoAssistant/Associate/Professor of Chemistry & BiochemistryJul 2001–Jun 2010Academic leadership

External Roles

OrganizationRolePublic/PrivateTenureNotes
Enliven Therapeutics, Inc. (ELVN)DirectorPublicSince Dec 2020Current board seat
MoonLake Immunotherapeutics, Inc. (MLTX)DirectorPublicSince Apr 2021Current board seat
Aleksia Therapeutics, Inc.President & CEOPrivateSince Aug 2022Operating role
Nexo Therapeutics, Inc.President & CEOPrivateSince Aug 2022Operating role
Blossom Bioscience Ltd.CEOPrivateSince Jun 2021Operating role

Board Governance

  • Chairperson of the Board; roles of chair and CEO are separated to strengthen independent oversight .
  • Committee assignments: Audit Committee member; Compensation Committee Chair and member .
  • Independence: Board determined Phillips is independent under Nasdaq rules (five of seven directors are independent) .
  • Attendance: In FY2024, the Board held eight meetings; each director attended at least 75% of Board and committee meetings for which they served .
  • Engagement: Audit Committee met four times; Compensation Committee met two times in FY2024, with Phillips participating and leading compensation oversight .
  • Executive sessions and governance policies: Non-employee directors meet in executive session periodically; strong governance and code of ethics framework in place .

Fixed Compensation

ComponentPolicy Amount (Annual)Andrew Phillips 2024 ActualNotes
Director Annual Retainer (cash)$40,000$21,336 Annual retainer policy; partial period earned due to merger timing
Chair of the Board$30,000Included in policyPolicy rate for non-employee Chair
Compensation Committee Chair$10,000Included in policyPhillips is Chair
Audit Committee Member$7,500Included in policyPhillips is member
Meeting FeesNone disclosedNo meeting fees disclosed
Election to receive RSUs in lieu of cashAvailable (100% of retainers)None elected for 2024RSU retainer election optional; none elected in 2024

Aggregate director compensation earned by Phillips in 2024: Fees earned $21,336; Option awards grant-date fair value $247,557; Total $268,893 .

Performance Compensation

Award TypeGrant/PolicyShares/ValueVestingNotes
Closing Award (stock options)Granted at merger close15,300 options outstanding ; Phillips grant-date value $247,557 Monthly over 36 months, equal installments, subject to continued service Exercise not permitted until S-8 effective (Dec 9, 2024)
Annual Award (stock options)Policy: 7,650 options after each Annual MeetingPer policyVests in full by next Annual Meeting or 1-year anniversary, subject to service Prorated if partial year service
Change-in-Control (director awards)Policy-based accelerationN/AFull acceleration of non-employee director awards granted while serving as director Applies to director grants upon CIC per Plan/policy

No performance-based metrics (TSR, EBITDA, ESG) are tied to director equity awards; vesting is service-based per policy .

Other Directorships & Interlocks

CompanyTypeRolePotential Interlocks/Relationships
Enliven Therapeutics (ELVN)Public biotechDirectorNone disclosed with OKUR
MoonLake Immunotherapeutics (MLTX)Public biotechDirectorNone disclosed with OKUR
Cormorant Asset ManagementInvestment firmFormer Managing Director (2020–2022)Entities affiliated with Cormorant are 5%+ holders and PIPE investors in OKUR; Board reaffirmed Phillips’ independence

Expertise & Qualifications

  • Biotech operating executive and scientist; prior CEO/President/CSO roles in clinical-stage oncology drug development (C4 Therapeutics) and translational R&D leadership (Broad Institute) .
  • Academic pedigree (Professor at Yale and University of Colorado) and degrees in biochemistry and chemistry, underpinning scientific governance .
  • Capital markets/finance experience (CFO of Helix Acquisition Corp.), relevant for audit and compensation oversight .

Equity Ownership

HolderBeneficial Ownership (Class A)% of Class AComponents
Andrew Phillips, Ph.D.2,550 shares via options exercisable within 60 days<1%Options exercisable within 60 days; outstanding director options total 15,300 shares
  • Hedging and pledging prohibited: Company insider trading policy bans short sales, public options, hedging transactions, and pledging of company stock by directors .
  • Outstanding director awards: 15,300 options; no RSUs outstanding for Phillips as of Dec 31, 2024 .

Governance Assessment

  • Strengths: Independent Chair; dual committee service with Compensation Committee chair role; strong governance framework (prohibition on hedging/pledging; executive sessions; codes/policies); confirmed independence despite historical buy-side affiliation .
  • Engagement: Board and committees met regularly in FY2024; directors ≥75% attendance, signaling baseline engagement .
  • Alignment: Director equity via service-based options (Closing Award) and annual option policy aligns compensation with shareholder value creation over time; optional RSU election in lieu of cash retainers provides additional equity alignment, though not used in 2024 .
  • Watch items: Multiple concurrent external CEO roles (Aleksia, Nexo, Blossom) warrant monitoring for bandwidth and potential conflicts if overlapping business dealings arise; board independence determination currently addresses conflict risk .
  • Related-party exposure: No Phillips-specific related-party transactions disclosed; broader related-party items include PIPE participation by major holders and a sublease with Ambros Therapeutics (former Reneo CEO), reviewed under the Related Person Transactions Policy and approved by the Audit Committee .

RED FLAGS: None disclosed for Phillips regarding related-party transactions, hedging/pledging, or attendance; independence affirmed by the Board .