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Jason Leverone

Chief Financial Officer at OnKure Therapeutics
Executive

About Jason Leverone

Jason Leverone, C.P.A., is Chief Financial Officer of OnKure Therapeutics, Inc. (OKUR). He has served as CFO since the closing of the Reneo–OnKure merger on October 4, 2024, and previously as Legacy OnKure’s CFO since January 2022. He is 51, holds a B.S. in business administration from Bryant University, and is a Certified Public Accountant; prior roles include public accounting at Ernst & Young LLP and Arthur Andersen LLP . Company operating metrics indicate pre-revenue biotech status, with quarterly EBITDA of -$17.7M (Q4’24), -$16.9M (Q1’25), -$16.2M (Q2’25), and -$15.4M (Q3’25), reflecting sequential improvement as programs advance.*

Past Roles

OrganizationRoleYearsStrategic Impact
Viridian Therapeutics (NASDAQ: VRDN; formerly miRagen)Chief Financial Officer & SecretaryNov 2008 – May 2021Guided reverse merger and financing transition; long-tenured public biotech finance leadership
Replidyne, Inc.Senior Director of Finance & ControllerNov 2005 – Feb 2009Led public-company controllership and finance operations
Ernst & Young LLPPublic AccountingEarly careerAudit and advisory foundation
Arthur Andersen LLPPublic AccountingEarly careerAudit and advisory foundation

External Roles

No public company board roles or external directorships are disclosed for Mr. Leverone in OKUR’s proxy .

Fixed Compensation

Component2024Notes
Base Salary ($)$382,958 Actual paid in year; base set to $444,000 post-merger effective 10/4/2024
Target Bonus (%)40% of base OKUR new employment agreement
Target Bonus ($)$177,600 40% of $444,000
Actual Bonus Paid ($)$168,501 (paid 2025) Discretionary based on corporate goals
Other Comp ($)$13,799 (401k match) Standard benefits

Summary compensation:

YearSalary ($)Bonus ($)Stock Awards ($)Option Awards ($)All Other Comp ($)Total ($)
2024382,958 168,501 2,113,312 13,799 2,678,570
2023346,500 91,476 311,684 28,972 13,315 791,947

Performance Compensation

2024 annual bonuses were discretionary; the Board assessed company performance against corporate goals. No specific metric weightings or payout curves are disclosed .

MetricWeightingTargetActualPayoutVesting
Discretionary corporate goalsNot disclosed Not disclosed Qualitative assessment $168,501 Cash (paid 2025)

Executive Incentive Compensation Plan was adopted at merger close; 2024 bonuses for NEOs were not governed by this plan .

Equity Ownership & Alignment

Total beneficial ownership (as of March 1, 2025):

HolderShares Beneficially OwnedOwnership %Components
Jason Leverone, C.P.A.41,353 <1% 33,188 options exercisable within 60 days ; 8,165 RSUs vesting within 60 days

Outstanding awards and vesting:

Award TypeGrant DateExercisable (#)Unexercisable (#)Exercise Price ($)ExpirationVesting Detail
Stock Option1/11/20224,215 1,566 21.20 1/10/2032 25% at 1/3/2023; then 1/48 monthly
Stock Option8/30/20232,217 3,105 13.99 8/29/2033 1/48 monthly starting 5/1/2023
Stock Option10/4/20247,256 123,355 18.20 10/3/2034 1/36 monthly starting 11/4/2024
RSULegacy OnKure 2023 RSU Plan16,331 unvested Service-based in quarterly tranches; liquidity condition satisfied 181 days post-merger (≈ Apr 3, 2025)

Policy alignment:

  • Hedging and pledging of company securities are prohibited for directors, officers, and employees .
  • Insider options/derivative trades (other than compensatory awards) and short sales are prohibited .

Ownership guidelines are not disclosed; compliance status not disclosed.

Employment Terms

New OKUR Employment Agreement (effective 10/4/2024):

  • Base salary $444,000; target annual bonus 40% of base ($177,600) .
  • Severance (non-CIC): 1x base salary lump sum; up to 12 months COBRA; requires release .
  • CIC Period (3 months before to 12 months after Change in Control): Double-trigger benefits of 1x base salary; 1x target bonus; up to 12 months COBRA; 100% acceleration of time-based equity awards; performance awards excluded from automatic acceleration .
  • 280G treatment: Best-net (cutback vs full) to maximize after-tax; no tax gross-ups .

Non-compete, non-solicit, and other post-termination covenants are not disclosed in the proxy.

Compensation governance:

  • Compensation Committee members: Andrew Phillips (Chair), Isaac Manke, Edward Mathers; independent per Nasdaq .
  • Consultants: Pearl Meyer (2024); Alpine Rewards, LLC retained March 2025 for peer group and benchmarking .
  • Annual outside director equity mechanics, change-in-control acceleration for non-employee directors under the Plan .

Performance & Track Record

Company operating metrics (sequential quarterly trend):

MetricQ4 2024Q1 2025Q2 2025Q3 2025
Revenues ($USD)n/a*n/a*n/a*n/a*
EBITDA ($USD)-17,736,000*-16,882,000*-16,207,000*-15,393,000*

Values retrieved from S&P Global.*

Qualitative context:

  • OKUR is a clinical-stage, pre-revenue biotech; EBITDA improvements reflect cost discipline and program phasing typical in development companies.*

Risk/related-party context:

  • Insider trading and pledging prohibitions reduce misalignment risk .
  • A related-party sublease was approved by the Audit Committee (Ambros Therapeutics; ≈$450,000 over term) .

Investment Implications

  • Pay-for-performance alignment: CFO compensation mixes market-based equity (options/RSUs) with moderate cash; 2024 bonus discretionary due to merger and integration, limiting metric transparency . Equity-heavy grants tie upside to value creation but also create calendar-driven vesting over 36–48 months .
  • Retention risk and change-in-control economics: Double-trigger CIC severance (1x base + 1x target bonus + acceleration of time-based awards) offers retention through a transaction but could motivate timing preferences; absence of tax gross-ups is governance-friendly .
  • Insider selling pressure: Significant unexercised options (123,355 from 10/4/2024 grant) vest monthly; RSUs met liquidity condition ~181 days post-merger, potentially increasing sale capacity—monitor Form 4s for actual activity as lock-ups expire and tranches vest .
  • Alignment safeguards: Prohibitions on hedging and pledging reduce downside protection strategies and collateral risks, maintaining skin-in-the-game .
  • Operating trajectory: Negative but improving EBITDA is consistent with pre-revenue biotech; equity awards incentivize long-term milestones. Focus diligence on financing runway, clinical catalysts, and potential strategic transactions that would trigger CIC mechanics.*

Citations:

*Values retrieved from S&P Global.