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Steven Rubin

Executive Vice President – Administration at OPKO HEALTHOPKO HEALTH
Executive
Board

About Steven Rubin

Steven D. Rubin, age 64, is Executive Vice President – Administration (since May 2007) and a director (since February 2007) of OPKO Health, bringing extensive legal, transactional, and pharmaceutical industry experience; current outside directorships include Red Violet (RDVT), Cocrystal Pharma (COCP), Eloxx Pharmaceuticals (ELOX), and ChromaDex (CDXC) . Company performance anchors used in compensation assessments include Adjusted Operating Income, Revenue, and Relative TSR; recent Pay vs Performance data show OPKO revenue and cumulative TSR as below .

MetricFY 2020FY 2021FY 2022FY 2023FY 2024
Revenue ($USD Thousands)1,435,413 1,774,718 1,004,196 863,495 713,142
Net Income ($USD Thousands)(30,586) (30,143) (328,405) (188,863) (53,224)
Company TSR (Value of $100 from 12/31/2019)268.71 327.21 85.03 102.72 100.00

Past Roles

OrganizationRoleYearsStrategic Impact
OPKO Health, Inc.Executive Vice President – AdministrationSince May 2007 Senior legal/business leadership supporting strategic planning, acquisitions, and regulatory/transactional affairs

External Roles

OrganizationRoleYearsStrategic Impact
Red Violet, Inc. (RDVT)DirectorCurrent Software/data services governance; strategic planning oversight
Cocrystal Pharma, Inc. (COCP)DirectorCurrent Biotech pipeline and governance; related-party exposure due to OPKO/insider holdings
Eloxx Pharmaceuticals, Inc. (ELOX/OTC)DirectorCurrent Clinical-stage biotech oversight
ChromaDex Corp. (CDXC)DirectorCurrent Nutraceutical oversight
Neovasc, Inc.DirectorPriorMedical device governance (prior role)
Non-Invasive Monitoring Systems, Inc. (NIMU)DirectorPriorMedical device governance (prior role)
VBI Vaccines, Inc. (VBIV)DirectorPriorVaccine development oversight (prior role)
Cogint/Fluent, Inc. (FLNT)Director (prior to spin-off)PriorInformation solutions/data analytics governance
Kidville, Inc.; Castle Brands, Inc. (ROX)DirectorPriorConsumer brands/cap markets exposure

Fixed Compensation

Component2022 ($)2023 ($)2024 ($)
Base Salary810,000 810,000 810,000
Cash Bonus400,000 400,000
All Other Compensation (401k etc.)12,200 13,200 13,800
Total Reported Compensation822,200 1,944,200 1,845,050

Notes:

  • Base salaries unchanged in 2023–2024 per Compensation Discussion and Analysis .

Performance Compensation

Equity AwardGrant DateUnits/OptionsExercise PriceGrant-Date Fair Value ($)Vesting Schedule
Stock Options5/18/2023700,000 $1.58 721,000 Four equal annual tranches starting 5/18/2024; expire 5/17/2033
RSUs (time-based)7/24/2024437,500 621,250 50% on 7/24/2026; 25% on 7/24/2027; 25% on 7/24/2028

Upcoming vesting-related supply signals:

  • Options: 175,000 vest annually each May 18 from 2024–2027; as of 12/31/2024, 175,000 were exercisable and 525,000 remained unexercisable .
  • RSUs: 218,750 units vest on 7/24/2026; 109,375 units vest on 7/24/2027; 109,375 units vest on 7/24/2028 .

Pay for performance metrics administration:

MetricWeightingTargetActualPayoutNotes
Adjusted Operating IncomeNot disclosed Not disclosedNot disclosedNot disclosedIdentified among “most important” measures used in 2024
RevenueNot disclosed Not disclosedSee About section revenue tableNot disclosedCompany-selected measure in pay-versus-performance
Relative TSRNot disclosed Not disclosedSee About section TSRNot disclosedConsidered in setting pay
Design ApproachNo set formula; equity grants discretionary, CEO-recommended for NEOs

Equity Ownership & Alignment

Date (Record)Beneficial Ownership (Shares)% of OutstandingOptions Included (Exercisable within 60 days)Notes
2/29/20248,512,732 1.22% (of 696,991,677) 2,325,000 SEC beneficial ownership definition applied
2/24/20258,512,732 1.26% (of 671,601,520/671,550,270) 2,325,000 Shares outstanding per proxy; ownership footnote confirms options
  • Outstanding option detail for Rubin at 12/31/2024 includes multiple prior grants (2015–2021) all exercisable plus 2023 grant partly exercisable; strike prices range $14.42 to $1.58; remaining 2023 options unexercisable total 525,000 .
  • Hedging/pledging policy: Directors/officers are prohibited from pledging, margin purchases, short selling, and derivatives without prior written consent; trading restricted to windows .

Employment Terms

  • No individual employment or change-in-control agreement for Steven Rubin; severance not provided (except offer letters for other executives) .
  • Plan-level change-in-control (CIC) acceleration: All awards under 2007 and 2016 Equity Incentive Plans fully vest upon a CIC, subject to assumption/replacement provisions .
  • Estimated value of Rubin’s option acceleration if CIC occurred on 12/31/2024: approximately $1,000,000 .
  • Pension/SERP/Deferred compensation: None for Named Executive Officers .

Board Governance

  • Board service: Director since 2007; management (non-independent) director; current role Executive Vice President – Administration and Director .
  • Committee roles: None—Rubin does not sit on Audit, Compensation, Governance/Nominating, Independent Investment, or Succession committees; all committees are chaired and populated solely by independent directors .
  • Board leadership: OPKO combines CEO and Chairman roles (Dr. Frost); Lead Independent Director is Richard C. Pfenniger, Jr.; independent directors head all standing committees .
  • Board meetings and independence: Majority independent; board met six times in FY 2024; executive sessions at least twice annually .

Director Compensation

  • Non-employee director program: $30,000 annual cash retainer; annual option grants (30,000); committee and chair retainers (Audit $15,000; Compensation $7,500; Audit Chair additional 15,000 options; Lead Independent Director $10,000 + 15,000 options) .
  • FY 2024 non-employee director totals disclosed (Rubin is an employee director; proxy tables cover non-employee directors) .

Compensation Committee Analysis

  • Composition: Independent directors—Chair Richard M. Krasno, members Prem A. Lachman and Roger J. Medel (FY 2024) .
  • Process: Heavily relies on CEO recommendations for NEOs (other than CEO); equity awards discretionary; no outside compensation consultant retained to set director/officer pay; internal benchmarking across ~12 industry companies used .
  • Policy stance: Pay mix includes salary, discretionary bonus, and equity; historical targeting of base salary near median peers .

Related Party Transactions (context relevant to Rubin’s network)

  • OPKO holds minority stakes in entities with executive/board overlap (including Cocrystal Pharma, ChromaDex, Non-Invasive Monitoring Systems, Eloxx, BioCardia, LeaderMed); considered related-party due to management’s ownership interests and/or board representation; Audit Committee oversees approvals .
  • Other RPT highlights: NextPlat e-commerce agreement (Frost interest >20%); lease with Frost Real Estate; BioReference purchases from Danaher subsidiaries (Zerhouni director at Danaher); aircraft reimbursement for company-related travel (Frost-owned plane) .

Say-on-Pay & Shareholder Feedback

  • Say-on-Pay support: ~97% approval at 2024 annual meeting ; ~97% approval at 2023 annual meeting .
  • Frequency: Annual advisory vote .

Performance & Track Record

  • Company-selected pay vs performance measure: Revenue; additional measures include Adjusted Operating Income and Relative TSR .
  • 2020–2024 revenue declined from $1.44B to $0.71B; net losses narrowed in 2024; TSR over the same five-year window shows volatility and normalization to ~100 as of 2024 .

Risk Indicators & Red Flags

  • Governance concentration: Combined CEO/Chair and multiple management directors; mitigated by independent committees and Lead Independent Director .
  • Single-trigger CIC acceleration of awards may weaken retention post-transaction and increase dilution risk upon change in control .
  • Trading/hedging restrictions exist but are permissive with prior consent; monitor for pledging exceptions .
  • Related-party ecosystem across investees (board overlaps) requires continued Audit Committee oversight .

Investment Implications

  • Alignment: Rubin’s beneficial ownership of 1.26% and 2.325M options (many already exercisable) indicate meaningful skin-in-the-game; upcoming RSU and option vesting windows (2026–2028 and annually through 2027) present identifiable supply overhangs around those dates .
  • Incentive design: Equity remains core; metrics considered include Revenue, Adjusted Operating Income, and Relative TSR, but awards are largely discretionary and CEO-recommended—monitor pay-for-performance rigor in a period of declining revenues .
  • Retention/contract risk: No employment agreement or severance for Rubin; retention relies on unvested equity; CIC single-trigger acceleration may reduce post-deal retention leverage .
  • Governance: Strong independent committee structure and high Say-on-Pay support (~97%) offset combined CEO/Chair concerns; Rubin’s multiple outside boards broaden network/intelligence flow but pose time-allocation considerations .