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Avril McKean Dieser

Director at OS Therapies
Board

About Avril McKean Dieser

Avril McKean Dieser (age 52) joined the OSTX board on October 28, 2024. She is Vice President, Head of Legal Patient Evidence at UCB, Inc., with prior roles at AbbVie and two Atlanta corporate law firms. She holds a J.D. from Catholic University, an M.A. in Public Administration from University of Maryland (European Division), and a B.A. from Duquesne; she is admitted in Georgia and Illinois. The proxy emphasizes her 21+ years in pharmaceutical regulatory/commercialization, corporate controls, and governance; she also brings a patient-advocacy perspective after losing her son to osteosarcoma in January 2024 .

Past Roles

OrganizationRoleTenureCommittees/Impact
UCB, Inc. (subsidiary of UCB S.A.)Vice President, Head of Legal Patient EvidenceAug 2016–present; previously Apr 2008–Apr 2013Leads attorneys supporting global assets, payer functions, regulatory/medical/patient communities and clinical development
AbbVie Inc.Legal team – global product support (immunology/oncology); government pricing lawyer for pharma/combination productsMay 2013–Jul 2016Global product support; pricing compliance
Corporate law firms (Atlanta, GA)Corporate attorneyPrior to 2008 (dates not specified)Corporate law practice; governance and controls experience

External Roles

OrganizationRoleTenurePublic/PrivateNotes
None disclosedNo other public company directorships or external board roles disclosed in proxy

Board Governance

  • Independence: The board determined all directors except the CEO (Paul Romness) are independent under NYSE American and SEC rules; Avril is independent .
  • Board leadership: Combined CEO/Chairman structure; no lead independent director referenced in the proxy’s leadership section .
  • Committees: Audit Committee member; Audit Chair is John Ciccio; other members include Theodore F. Search .
  • Committee responsibilities: Audit oversight includes auditor selection, financial reporting, internal controls, and related-party transaction review .
  • Attendance: In 2024, the board met four times and each director attended at least 75% of board and committee meetings; executive sessions are held regularly .
  • Tenure on OSTX board: Since October 28, 2024 .

Fixed Compensation

ComponentFY 2024Notes
Cash fees$0 Non-employee director policy pays only a $5,000 annual retainer to the Chairman; no cash for members or committee chairs; no meeting fees
Equity (options, grant-date fair value)$24,505 Non-employee director option award fair value; specific strike/vesting not disclosed for directors
Other compensation$0
Policy ElementAmountApplicability
Annual retainer – Chairman$5,000 Paid to Chairman only
Annual retainer – Members$0 No cash retainer for non-employee directors
Committee chair fees$0 No additional chair retainers
Meeting fees$0 None; reasonable expenses reimbursed

Performance Compensation

Metric/StructureFY 2024 DisclosureDetails
Director performance-linked metrics (e.g., TSR, revenue, ESG)Not disclosed Director compensation comprised option grants; proxy does not specify performance metrics for directors
Equity plan features (company-wide)Performance awards permitted under 2023 Plan; committee may set business/personal criteria Plan allows performance units/shares; change-in-control acceleration at committee’s discretion

Other Directorships & Interlocks

CategoryDisclosureNotes
Current public company boardsNone disclosed
Private/non-profit/academic boardsNot disclosed
Interlocks (competitors/suppliers/customers)Employment at UCB (global biopharma) noted; no OSTX related-party ties disclosedBiography notes UCB role; related-party section lists transactions involving other parties but none involving Avril

Expertise & Qualifications

  • Pharmaceutical regulatory and commercialization expertise; payer/regulatory/medical/patient evidence leadership .
  • Corporate governance and controls; 21+ years legal/compliance experience .
  • Legal credentials: J.D.; bar admissions in GA and IL; advanced public administration training .
  • Patient advocacy perspective relevant to osteosarcoma—a core OSTX focus .

Equity Ownership

HolderShares Beneficially Owned% of ClassNotes
Avril McKean Dieser2,500 * (<1%) As of Aug 20, 2025; no director-specific option detail disclosed beyond grant fair values

Insider Trades

ItemDisclosureNotes
Section 16 filingsFiled Form 5 due to failure to file a Form 4 for transactions on Dec 5, 2024 Administrative delinquency noted alongside several insiders; no further transaction detail provided in proxy

Governance Assessment

  • Strengths:
    • Independent director with deep regulatory/legal expertise; positioned to strengthen Audit Committee oversight, including related-party review .
    • Audit Committee membership and participation in auditor selection and financial reporting oversight enhance board effectiveness .
    • Attendance at or above 75% supports engagement and board effectiveness .
    • Equity-based director pay (options) aligns incentives with shareholders, conserving cash appropriate for an emerging biopharma .
  • Concerns / RED FLAGS:
    • No formal insider trading policy or hedging policy adopted as of August 2025; board intends to adopt, but absence is a governance gap .
    • Combined CEO/Chairman with no disclosed lead independent director may weaken independent oversight .
    • Section 16(a) delinquent filing (Form 5) indicates administrative control weaknesses; minor but notable .
    • Low direct ownership (2,500 shares, <1%) suggests limited “skin in the game”; reliance on options for alignment .

Overall implications: Avril’s legal/regulatory depth and Audit Committee role are positives for controls and compliance. However, OSTX’s pending adoption of insider trading/hedging policies, combined leadership structure, and Section 16 delinquencies should be monitored as governance risk factors that can affect investor confidence .