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Emil Chuang

Director at PALISADE BIOPALISADE BIO
Board

About Emil Chuang

Emil Chuang, MB BS FRACP, age 65, is a pediatric gastroenterologist and veteran drug developer with ~25 years across large pharma, biotech, medical nutrition, and diagnostics. He was appointed to Palisade Bio’s Board on July 7, 2025, and is currently CMO at Intrinsic Medicine and principal of Chuang Global Consulting; prior roles include leadership positions at Nestlé Health Science (Head of GI Clinical Development), Takeda (Head of GI Translational Research and Early Clinical), and Progenity (Head of GI Precision Medicine) . He trained at the University of Sydney (MB BS), completed pediatrics specialty training in Australia (FRACP), and held assistant professorships at Duke University and the University of Pennsylvania .

Past Roles

OrganizationRoleTenureCommittees/Impact
Duke UniversityAssistant Professor (Pediatrics/GI)Prior to industryAcademic clinical leadership
University of PennsylvaniaAssistant Professor (Pediatrics/GI)Prior to industryAcademic clinical leadership
TakedaHead of GI Translational Research and Early ClinicalPrior roleLed GI translational/early clinical programs
Nestlé Health ScienceHead of GI Clinical DevelopmentPrior roleLed GI clinical development
ProgenityHead of GI Precision MedicinePrior rolePrecision medicine leadership
Chuang Global ConsultingFounder/Principal2020–PresentAdvisory practice
Intrinsic Medicine (private)Chief Medical Officer2021–PresentCMO for IBD-focused biotech

External Roles

OrganizationRoleTenureNotes
Intrinsic Medicine (private)Chief Medical Officer2021–PresentNo public company directorships disclosed
Chuang Global ConsultingPrincipal2020–PresentIndependent advisory

Board Governance

  • Current assignments (as of Sep 12, 2025): Audit Committee member; Compensation Committee Chair; Governance & Nominating Committee member .
    • Committee composition and chair roles confirmed: Williams (Audit Chair, G&N Chair), Chuang (Compensation Chair), Wei (Audit and G&N member) .
  • Independence: Board determined Dr. Chuang is independent under Nasdaq rules; the Board maintains an independent Chair (Donald Williams) .
  • Election/tenure: Appointed July 7, 2025; elected by stockholders on Oct 17, 2025 (Votes For: 659,895; Withheld: 76,636; Broker Non-Votes: 2,849,169) .
  • Attendance: For 2024, the company reports all directors attended at least 75% of Board and committee meetings; independent directors met in executive session four times (note: Dr. Chuang joined in 2025) .

Fixed Compensation

Current Non-Employee Director Cash Retainer Policy (amended Feb 22, 2023):

ComponentAmount (USD)
Annual Board retainer$40,000
Chair of the Board (additional)$35,000
Committee Chair retainers (Audit / Compensation / Governance & Nominating)$20,000 / $15,000 / $10,000
Committee Member retainers (Audit / Compensation / Governance & Nominating)$10,000 / $7,500 / $5,000

Notes:

  • Equity for non-employee directors is granted ad hoc (options and/or RSUs) to balance retention vs. dilution; expenses reimbursed per policy .

Performance Compensation

Award TypeGrant/Action DateQuantityInstrument/TermsVesting/SettlementSource
Director option grant (upon appointment)2025-07-078,000Non-statutory stock options; exercise price equal to closing price on grant date; 2021 EIP formVesting not specified in 8-K
Phantom Unit Plan adoption2025-09-04Plan up to 10,000,000 unitsCash-settled Phantom Units; no shareholder vote requiredDirectors’ units vest in 3 annual installments on Aug 5 (starting 2026); payout upon termination (12 monthly installments), CoC (lump sum), or 7th anniversary
Phantom Units (director grant)2025-09-0418,800Phantom Units (Form 4)Director vesting schedule above (Aug 5 annually over 3 years)[ReadFile /tmp insider JSON lines 41–56]
Phantom Units (per 8-K disclosure)2025-09-0437,6008-K states “other independent directors were each granted 37,600 Phantom Units”As above
RSUs2025-10-06 (filed 2025-10-08)510,700Restricted Stock Units (price $0)Not disclosed[ReadFile /tmp insider JSON lines 22–38]
RSUs (amended)2025-10-06 (filed 2025-11-06)60,600RSUs (Form 4/A correction)Not disclosed[ReadFile /tmp insider JSON lines 4–20]
Phantom Plan termination2025-10-22Company terminated the Plan; filing specifies executive Phantom Units were unvested and terminatedFiling does not explicitly state treatment of director Phantom Units

Important notes:

  • The Oct 8 Form 4 reporting 510,700 RSUs was amended on Nov 6 to 60,600 RSUs, indicating a significant correction to the award amount [ReadFile /tmp insider JSON lines 22–38, 4–20].
  • The company terminated the Phantom Unit Plan on Oct 22, 2025; the 8-K explicitly states executive Phantom Units were terminated unvested and for no consideration; it does not explicitly state the treatment of director Phantom Units, creating potential ambiguity for director grants .

Other Directorships & Interlocks

CompanyRoleCommittee rolesPotential interlocks
None disclosed (public companies)None disclosed

Expertise & Qualifications

  • Pediatric gastroenterologist with extensive IBD development experience; contributed to programs including infliximab (pediatric Crohn’s) and vedolizumab; noted involvement in two regulatory approvals: infliximab (pediatric Crohn’s) and lorcaserin (morbid obesity) .
  • 80 peer-reviewed publications/abstracts/book chapters .

  • Board-designated independent director; Compensation Committee Chair .

Equity Ownership

MetricAs ofAmountNotes
Beneficial ownership (shares)2025-10-13667Footnote indicates includes 667 shares underlying options; “less than 1%” ownership
Shares outstanding (for calc)2025-10-13133,002,572Company share count used in table

Additional alignment considerations:

  • Hedging/pledging prohibited by Company policy; directors, officers, employees (and covered family members) may not engage in short sales, options, or hedging; no margining of Company stock allowed .
  • Ownership guidelines for directors not disclosed in 2024–2025 filings reviewed.

Insider Trades and Holdings (Form 3/4 summary)

Filing DateTransaction DateFormTypeSecurityQuantityPost-Transaction OwnershipURL
2025-07-173Initial statement0https://www.sec.gov/Archives/edgar/data/1357459/000164117225020084/0001641172-25-020084-index.htm
2025-09-052025-09-044AwardPhantom Units18,80018,800https://www.sec.gov/Archives/edgar/data/1357459/000149315225012689/0001493152-25-012689-index.htm
2025-10-082025-10-064AwardRSUs510,700510,700https://www.sec.gov/Archives/edgar/data/1357459/000149315225017473/0001493152-25-017473-index.htm
2025-11-062025-10-064/AAward (amended)RSUs60,60060,600https://www.sec.gov/Archives/edgar/data/1357459/000149315225021132/0001493152-25-021132-index.htm

Data source: insider-trades skill output (Form 3/4 SEC links shown).

Governance Assessment

  • Strengths

    • Independent director with deep GI/IBD development expertise; enhances clinical oversight for PALI’s IBD pipeline .
    • Committee influence: Chairs Compensation Committee; serves on Audit and Governance & Nominating, indicating strong engagement in key oversight areas .
    • Independent Chair structure and explicit independence determinations bolster board effectiveness .
  • Potential concerns / Watch items

    • Ownership alignment: Beneficial ownership reported at only 667 shares as of Oct 13, 2025 (options within 60 days), i.e., de minimis skin-in-the-game; while equity awards (RSUs/options/phantom units) were granted, vesting and settlement clarity is mixed due to the Phantom Plan’s termination and amended RSU reporting [ReadFile /tmp insider JSON].
    • Compensation structure changes: Adoption of a cash-settled Phantom Unit Plan without shareholder approval (permitted but less aligned than equity-settled) followed by termination ~6 weeks later; directors were disclosed as recipients (37,600 units each) but Form 4 shows 18,800 for Dr. Chuang; lack of clarity on director award treatment at plan termination is a governance uncertainty and potential investor confidence issue .
    • Administrative correction: Large RSU award reported then amended significantly downward (510,700 → 60,600); while amendments happen, magnitude suggests prior error—investors may scrutinize equity award controls [ReadFile /tmp insider JSON lines 22–38, 4–20].
  • Shareholder support signal

    • 2025 director election results: Votes For 659,895; Withheld 76,636 (broker non-votes 2,849,169) indicate support among votes cast .
  • Related-party/Conflicts

    • No related-party transactions involving Dr. Chuang disclosed; Company has a formal Related-Person Transactions Policy overseen by the Audit Committee .
    • No public company interlocks or supplier/customer relationships disclosed for Dr. Chuang .
  • Compensation policy context

    • Cash fees and committee retainers disclosed and standard for small-cap biotech; equity for directors granted ad hoc to manage dilution—transparent but discretion-driven approach requires clear disclosure of grant rationale and vesting to maintain investor confidence .

Other Directorships & Interlocks

No current public company board seats disclosed; external roles limited to Intrinsic Medicine (private) and consulting practice .

Performance & Track Record (selected highlights)

  • Clinical development contributions include infliximab (pediatric Crohn’s) and lorcaserin approvals; extensive IBD portfolio experience (e.g., vedolizumab) .

Equity Ownership

CategoryDetail
Beneficial ownership667 shares (via options exercisable within 60 days), <1%
Not counted as beneficial (illustrative)RSUs (60,600 per 11/6/25 Form 4/A); Phantom Units (18,800 per Form 4; 37,600 per 8-K disclosure) as they are unvested and/or cash-settled [ReadFile /tmp insider JSON]
Policy safeguardsHedging/pledging prohibited for directors

Compensation Structure Details (selected policy features)

  • Ad hoc equity approach for non-employee directors (options/RSUs) to balance retention with dilution risk .
  • Clawback policy (Oct 2, 2023) applies to executive incentive compensation after restatements; not specifically to director equity grants; company notes it historically has not granted restatement-based incentive pay .

Signals for Investors

  • Positive: Independent, domain-expert director leading Compensation Committee; governance structures (independent chair, active committees) in place .
  • Caution: Award administration clarity (amended RSU grant) and rapid Phantom Plan reversal warrant continued monitoring for disclosure and control robustness; low immediate ownership until equity vests may limit alignment optics in near term [ReadFile /tmp insider JSON] .