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Sue Browne

Chief Scientific Officer at Passage BIO
Executive

About Sue Browne

Sue Browne, Ph.D., is Passage Bio’s Chief Scientific Officer and joined the company in June 2021 after leading Biology and Biomarkers/Precision Medicine; she specializes in drug discovery and development for neurodegenerative, neuropsychiatric, and rare CNS diseases . She has publicly presented PBFT02 program data and strategy, including preclinical and interim clinical findings for FTD-GRN at the ESGCT Annual Conference on October 24, 2024, underscoring her leadership of Passage’s lead gene therapy asset . Passage Bio’s 2024 Annual Report and investor materials list her among the leadership team, confirming her role at the company during 2024–2025 . Note: Passage Bio’s 2025 proxy lists executive officers for SEC purposes as CEO, CFO, and General Counsel; Browne is not included in that Section, which limits proxy-based disclosure of her compensation and beneficial ownership .

Past Roles

OrganizationRoleYearsStrategic Impact
Passage BioVP Biology; Head of Biomarkers & Precision Medicine; Chief Scientific Officer2021–presentLed translational biology and biomarker/precision medicine; advanced PBFT02 and broader CNS gene therapy strategy
Acadia PharmaceuticalsExecutive Director, Translational Research & External Innovation2019–2021Drove strategic expansion of CNS pipeline and external innovation initiatives
Teva PharmaceuticalsDirector, Small Molecule Discovery Research~5 yearsLed small molecule discovery programs across CNS therapeutic areas
Merck Research LaboratoriesDepartment of Neuroscience~7 yearsConducted neuroscience research underpinning neurodegenerative drug discovery
Weill Cornell (Cornell University’s Weill Graduate School of Medical Science)Assistant Professor, Neuroscience Program & Neurology1999–2006Academic research on etiologies of neurodegenerative disorders (Huntington’s, ALS, Parkinson’s)
Massachusetts General HospitalPostdoctoral Research, NeurologyPre-1999Postdoctoral work in neurology supporting subsequent academic and industry CNS focus

External Roles

OrganizationRoleYearsNotes
Huntington’s Disease Society of America (HDSA)Scientific Advisory Board MemberSince 2015Long-standing advisory role reflecting domain expertise in Huntington’s disease

Equity Ownership & Alignment

  • The 2025 proxy’s beneficial ownership table lists directors, named executive officers (NEOs), and 5% holders; Browne is not included among executive officers or directors in that section, and her specific equity holdings are not disclosed there .
  • Executive officers listed for SEC purposes as of March 31, 2025 are CEO William Chou, CFO Kathleen Borthwick, and General Counsel Edgar B. (Chip) Cale, limiting proxy-based visibility into Browne’s pay and ownership details .

Employment Terms

  • Passage Bio adopted a Compensation Recovery (Clawback) Policy on October 12, 2023 applicable to “Covered Employees” including current and former executive officers and Section 16 officers; incentive-based compensation must be recovered in the event of a restatement with overpayment over the prior three years .
  • The 2025 proxy details employment agreements and severance for CEO, CFO, and General Counsel; no Browne-specific employment agreement or severance terms are disclosed in the proxy .

Investment Implications

  • Limited direct disclosure: Browne appears as CSO in company materials and 8-K investor presentations, but is not an SEC-listed executive officer in the 2025 proxy; therefore pay, bonus metrics, vesting schedules, and ownership detail are not available via proxy tables, constraining pay-for-performance analysis and insider alignment assessment .
  • Governance safeguard: Passage Bio’s Clawback Policy applies to incentive compensation of Covered Employees, enhancing downside protection against misreported performance; whether Browne is a covered executive under Section 16 would determine applicability to her awards .
  • Execution signal: Browne’s leadership of PBFT02 and public presentation at ESGCT demonstrates direct influence on the company’s lead asset and clinical strategy; continued program milestones are likely the principal drivers of value creation attributable to R&D leadership .
  • Monitoring priorities: Track future 8-K Item 5.02 filings for any CSO compensation or contract changes, and watch DEF 14A updates for inclusion among NEOs; monitor Form 4 filings if Browne is designated a Section 16 officer to assess insider transactions and potential selling pressure .