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Marcelo Bigal

Director at Pacira BioSciencesPacira BioSciences
Board

About Marcelo Bigal

Independent director since October 2023 and Chair of the Science & Technology Committee; age 55. Dr. Bigal is President & CEO of Ventus Therapeutics and holds an M.D. and Ph.D. from the University of São Paulo, with 20+ years in pharma R&D, >330 peer‑reviewed publications, and recognition including the American Academy of Neurology’s Harold G. Wolff Award . He is designated independent under Nasdaq/SEC rules; 8 of 9 directors are independent (CEO excepted) . Board met 12 times in 2024, and each member attended at least 75% of board/committee meetings during their service period .

Past Roles

OrganizationRoleTenureCommittees/Impact
Ventus TherapeuticsPresident & CEO2019–presentLeads clinical-stage pipeline; senior R&D leadership experience applied to Pacira’s R&D oversight .
Versant VenturesVenture Partner2019–2023Venture investing and governance experience .
Purdue PharmaChief Medical Officer & SVP2018–2019CMO leadership in neurology/pain .
Teva Pharmaceutical IndustriesHead Specialty R&D & CSO; CMO & Head Global Specialty Clinical Dev; prior roles2014–2018Oversaw development/commercialization of Ajovy and Austedo; led global R&D teams >600 people .
Labrys Biologics (acquired by Teva)Chief Medical Officer2013–2014Migraine biologics development (CGRP) .
MerckGlobal Director, Scientific Affairs (Neuro/Psych); Head, Investigator Study Program2007–2013Scientific engagement, investigator-initiated studies .

External Roles

EntityRole/CapacityPublic company?
Ventus TherapeuticsPresident & CEONot listed as a current public company board; Bigal holds zero current public company directorships per proxy summary .
Santa Ana BioDirector (since 2023)Not counted as current public company board in PCRX proxy .
Coda BiotherapeuticsDirector (2019–2022)Prior directorship, not current .

Board Governance

AttributeDetail
IndependenceIndependent director; Board currently 8 of 9 independent directors (CEO excepted) .
CommitteesChair, Science & Technology; members include Froimson and Kronenfeld; S&T met 3x in 2024 . Committee structure re-affirmed Jan 28, 2025 8‑K .
AttendanceBoard met 12x in 2024; each member attended ≥75% of board/assigned committees .
Board leadershipIndependent Chair (Laura Brege) appointed Jan 28, 2025 .
Voting standardBylaws amended to adopt majority voting standard in uncontested elections (Mar 2025) and director resignation policy .
Executive sessionsNon‑employee directors held executive sessions at each regular board meeting in 2024 .

Fixed Compensation

ComponentPolicy/StructureBigal 2024 Actual
Cash retainersBoard/committee retainers paid quarterly; Chair/Member retainers: Audit ($30k/$15k), Comp ($24k/$12k), NGS ($18k/$9k), S&T ($18k/$9k). Board Chair +$50k; Lead Director +$35k .Fees earned or paid in cash: $65,429 .
Annual equity (time‑based)Effective July 1, 2024, annual stock award target increased to $300,000 split 50% RSUs / 50% stock options; RSUs and options vest 1 year from grant; change‑in‑control: 100% accelerate .Stock awards (RSUs): $149,996; Option awards: $150,009; Total 2024 director comp: $365,434 .
Initial equity grant (new directors)$450,000 stock options vesting monthly over 3 years .N/A (appointed in 2023; initial grant reflected in 2023 table) .

Notes:

  • Director equity grants are time-based; no performance metrics disclosed for director awards .
  • Non-employee directors reimbursed for reasonable meeting travel/expenses .

Performance Compensation

FeatureDetail
Performance metrics tied to director payNone disclosed; non‑employee director equity is time-based (RSUs/options) with 1‑year vest (initial options vest over 3 years) .
Change of control100% of then‑unvested director RSUs and options vest upon change of control or liquidation/dissolution (single trigger) .
Clawback policyCompany maintains an Incentive Compensation Recovery Policy (primarily applicable to executive incentive-based compensation) .

Other Directorships & Interlocks

AreaObservation
Current public company boardsBigal: 0 (minimizes overboarding/interlock risk) .
Related‑party transactionsProxy discloses related‑party items (e.g., former CEO transition), with no transactions involving Bigal reported for 2024–2025 .
Consultant conflictsIndependent compensation consultant retained for executive and director pay; independence assessed annually .

Expertise & Qualifications

  • Top skills cited: Government/Public Policy & Regulatory Affairs; Industry Experience; Research & Development; Scientific/Medical; Senior Leadership .
  • Career achievements include leading development/commercialization of fremanezumab (Ajovy) and deutetrabenazine (Austedo); leadership of >600‑person R&D teams; >330 publications; AAN Harold G. Wolff Award .
  • These credentials align with his role as Science & Technology Committee Chair overseeing R&D strategy and milestones .

Equity Ownership

MeasureAmount/Status
Total beneficial ownership39,528 shares; <1% of outstanding shares .
Options (vested)12,047 [as of 12/31/2024] .
Options (unvested)31,139 [as of 12/31/2024] .
RSUs (unvested)5,230 [as of 12/31/2024] .
Hedging/pledgingProhibited for directors under Insider Trading Policy (no short sales, derivatives, margin/pledging) .
Ownership guidelinesNon‑employee directors required to own ≥5x annual cash retainer within 4 years from later of Dec 10, 2024 or appointment; 2024 status: all current directors were compliant or within phase‑in .

Governance Assessment

  • Strengths

    • Independence and role fit: Independent director with deep R&D leadership chairs Science & Technology, matching board skills to oversight needs .
    • Attendance/engagement: Board disclosed ≥75% attendance by each member in 2024; regular executive sessions of independent directors .
    • Shareholder‑friendly governance: Majority voting standard adopted for uncontested elections in 2025; independent Board Chair appointed .
    • Alignment measures: Enhanced director stock ownership guideline to 5x retainer with structured phase‑in; anti‑hedging/pledging restrictions .
    • Low interlock/overboarding risk: Zero current public company directorships for Bigal per proxy summary .
  • Watch items / investor signals

    • 2025 say‑on‑pay failed (For 14.75M; Against 22.60M), indicating shareholder dissatisfaction with executive compensation; frequency vote favored annual (one‑year) advisory votes . 2024 say‑on‑pay had 90% approval, highlighting a sharp change in sentiment YoY .
    • Share pool increase approved (A&R 2011 Stock Incentive Plan +2.5M shares) may raise dilution scrutiny; annual non‑employee director total comp capped at $1,000,000 under plan .
  • Shareholder voting for director

    • Bigal re‑elected June 10, 2025: For 33,364,221; Withhold 4,017,587; Broker non‑votes 8,909,022 .
  • Insider trading

    • No recent Form 4 insider transactions located for Bigal in 2024–2025 search window (Forms 4 not found) — suggests no notable buying/selling activity disclosed during the period searched.

RED FLAGS

  • Failed 2025 say‑on‑pay vote signals heightened shareholder scrutiny of pay practices and board oversight of compensation; continued engagement and responsive changes may be expected by investors .

POSITIVE SIGNALS

  • Governance upgrades (majority voting, independent Chair) and strengthened ownership guidelines improve alignment and board accountability .

Appendix: Director Compensation Detail (2024)

MetricAmount
Cash retainer/fees (Bigal)$65,429
RSU grant date fair value (Bigal)$149,996
Option grant date fair value (Bigal)$150,009
Total compensation (Bigal)$365,434
Annual director equity policy (effective 7/1/2024)$300,000 total target award (50% RSUs / 50% options); 1‑year vest for annual grants; initial new director option grant $450,000 with monthly vest over 3 years; 100% acceleration on change of control .