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Stephan Toutain

Chief Operating Officer at PDS BiotechnologyPDS Biotechnology
Executive

About Stephan Toutain

Stephan F. Toutain, age 58, is Chief Operating Officer of PDS Biotechnology, appointed effective May 1, 2024. He holds an MBA from UNC Kenan-Flagler and a Master of Engineering in Biotechnology from University of Nancy II, with 30+ years of operational experience across drug development, commercial development, market access, and oncology/orphan markets . Tenure began May 1, 2024; 2024 compensation was primarily salary, a discretionary bonus, and an inducement stock option grant aligned to long-term value creation via clinical and regulatory milestones rather than traditional financial metrics . Company-level “pay versus performance” disclosures indicate the compensation framework emphasizes pipeline progress, with TSR and net loss reported at the company level, not individually; the 2024 NEO bonus outcomes reflected 50% achievement against corporate goals .

Past Roles

OrganizationRoleYearsStrategic Impact
Anavex Life SciencesChief Operating OfficerMay 2018 – Apr 2024Led operations during late-stage development; oncology and CNS exposure
Interleukin GeneticsChief Commercial OfficerJul 2016 – Aug 2017Commercial leadership; market access and commercialization
Alnylam PharmaceuticalsEarly Access Program (Advisor/Lead)Not disclosedBuilt early access program; rare disease commercialization readiness
Sarepta TherapeuticsGlobal Commercial Development LeadNot disclosedGlobal commercial build-out in orphan markets
Alexion PharmaceuticalsGeneral Manager, EuropeNot disclosedEuropean general management, rare disease commercial operations
Celgene; Johnson & JohnsonU.S. commercial, marketing, product managementNot disclosedBroad biopharma commercial leadership across portfolios

External Roles

  • None disclosed: No public company directorships or committee roles reported for Mr. Toutain .

Fixed Compensation

Metric2024Notes
Employment Agreement Base Salary$450,000 Effective at hire; subject to Board adjustments
2024 Actual Salary Paid (pro-rated)$300,000 Reflects May 1, 2024 start
Target Bonus %40% of base Discretionary; contingent on performance and employment through payment
Actual Bonus Paid (2024)$30,038 Paid March 2025, for 50% goal achievement
All Other Compensation (401k match)$9,750 Safe Harbor 401(k) match

Performance Compensation

Annual Cash Incentive (2024)

Metric CategoryWeightingTargetActualPayoutVesting/Timing
Corporate/Individual goals (R&D milestones, trials, regulatory, financings, org build, shareholder value) Not disclosed40% of base 50% achievement $30,038 Paid Mar 2025; employment through payment required

Equity Awards

Award TypeGrant DateSharesExercise PriceGrant Date Fair ValueVestingExpiration
Nonstatutory Stock Option (Inducement)May 1, 2024 / May 24, 2024 (plan grant record) 200,000 $3.61 $600,000 25% on 1st anniversary; remaining 75% monthly over 36 months, subject to continued service May 24, 2034
  • No RSUs/PSUs outstanding at 2024 year-end for NEOs; option-only profile .
  • Plan features: no discounted options; no repricing/buybacks without shareholder approval; clawback applies; no tax gross-ups under the plan .

Equity Ownership & Alignment

ItemDetail
Beneficial Ownership (as of Apr 17, 2025)54,167 shares via options exercisable within 60 days; 0 common shares directly owned
Shares Outstanding (Record Date)45,672,851
Ownership %≈0.12% (54,167 / 45,672,851)
Outstanding Options (Year-end 2024)200,000 unexercisable; $3.61; grant 05/24/2024; expire 05/24/2034
Vested/Exercisable within 60 days (as of Record Date)54,167
Pledging/HedgingProhibited without advance approval of Compliance Officer
Stock Ownership GuidelinesNot disclosed for executives
ClawbackAwards subject to mandatory clawback per corporate governance and exchange rules
  • Award history under Restated Plan: 200,000 options granted to Mr. Toutain since plan inception through Record Date .
  • Vesting schedule implies concentrated vest at first anniversary (May 24, 2025) then monthly vests thereafter, potentially creating periodic liquidity windows; lock-up/blackout policies may apply via insider trading policy .

Employment Terms

ProvisionEconomics/Terms
Start DateMay 1, 2024
Base/Bonus Eligibility$450,000 base; 40% target bonus
Severance (No Cause / Good Reason, post 90th day)12 months base salary + up to 12 months COBRA premium reimbursement
Severance (Company summary for COO)12 months base + 12 months benefits continuation
Change-in-Control (Protection Period)If terminated during Protection Period, bonus equal to target bonus; equity becomes 100% vested at closing if awards are assumed/continued
EquityEligibility for equity grants per plan and award agreements
Restrictive CovenantsConfidentiality, IP assignment, cooperation, non-compete, non-solicit, non-disparagement; general release required for severance
280G TreatmentCutback provision to maximize net after-tax amount (reduce only if it yields greater net after-tax)
Anti-Hedging/Anti-PledgingNo margin accounts, pledges, or hedging without advance approval

Investment Implications

  • Alignment and retention: Compensation mix skews to time-based options with four-year vesting and a CIC full acceleration if assumed/continued, balancing retention with potential windfall upon a transaction; severance is market-standard at ~1x salary plus benefits and CIC target bonus, moderate retention incentive .
  • Ownership and selling pressure: Direct share ownership is minimal (beneficial interests via options only), with material vesting milestones at first anniversary and monthly thereafter—watch Form 4s around vest dates for potential selling pressure, subject to insider trading windows and anti-hedging/pledging constraints .
  • Pay-for-performance: 2024 bonus paid at 50% achievement reflects discretionary linkage to clinical, regulatory, financing, and organizational objectives rather than revenue/EBITDA metrics typical of commercial-stage firms; this aligns incentives to development milestones but reduces near-term financial KPI alignment .
  • Governance risk mitigants: Plan prohibits option repricing/buybacks without shareholder approval, includes clawback, and lacks tax gross-ups; 280G cutback reduces excessive parachute risk—all supportive of shareholder-friendly governance .
  • Execution risk: Track record spans multiple rare disease and oncology programs across leading biopharmas and growth-stage companies; near-term value creation at PDS depends on advancing pivotal programs, with company-level TSR historically volatile per pay-versus-performance data, underscoring binary clinical/regulatory outcomes typical in late-stage biotech .