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Frank Karbe

Director at Phathom Pharmaceuticals
Board

About Frank Karbe

Frank Karbe (age 57) has served as an independent Class II director of Phathom Pharmaceuticals since April 2022. He brings 25+ years of finance and life sciences experience; he is currently Chief Financial Officer of Cidara Therapeutics (since February 2025) and previously served as CEO and director of Better Therapeutics (June 2022–March 2024), President/CFO at Myovant Sciences, and EVP/CFO at Exelixis; earlier roles include investment banking at Goldman Sachs and finance at Royal Dutch/Shell, with a Diplom Kaufmann from WHU–Otto Beisheim (Germany) . He is designated an independent director under Nasdaq rules and sits on PHAT’s Audit Committee; the Audit Committee’s financial expert is director Heidi Kunz (not Karbe) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Better Therapeutics, Inc.Chief Executive Officer and DirectorJun 2022 – Mar 2024CEO/board leadership during transition period
Myovant Sciences, Inc.President and Chief Financial Officer (CFO from Apr 2017; Principal Financial & Accounting Officer from Sep 2016)Sep 2016 – Aug 2021Public company finance leadership
The Color RunPresidentSep 2014 – Jul 2016Operating leadership
Exelixis, Inc.EVP & CFOJan 2004 – Jun 2014Scaled finance function at commercial-stage biotech
Goldman Sachs & Co.Vice President, Healthcare Investment Banking1997 – 2004Corporate finance/M&A advisor
Royal Dutch/Shell Group (Europe)Finance rolesPre-1997Corporate finance foundation

External Roles

OrganizationRoleTenureNotes / Interlocks
Cidara TherapeuticsChief Financial OfficerFeb 2025 – PresentPHAT director Theodore R. Schroeder is a Cidara director (interlock)
Aduro Biotech, Inc.Director (prior)Apr 2019 – Oct 2020Board service at public biotech (pre-merger into Chinook)
Arbutus Biopharma CorporationDirector (prior)2010 – 2018Board service at public biotech

Board Governance

ItemDetails
Board class/tenureClass II director; joined April 2022; current Class II term runs to the 2027 Annual Meeting
IndependenceBoard determined Karbe is independent under Nasdaq rules
Committees (current)Audit Committee member (appointed April 17, 2025); chair: Heidi Kunz
Committees (recent past)Compensation Committee member through Feb 29, 2024; Nominating & Corporate Governance Committee member during 2024 until April 17, 2025
AttendanceEach director attended ≥75% of board/committee meetings in FY2024
Annual meeting attendanceAll directors attended the 2024 annual meeting
Anti-hedging/pledgingCompany policy prohibits directors from hedging, shorting, margining or pledging company stock

Fixed Compensation

ComponentAmount/TermsSource
Annual cash retainer (non-employee directors)$50,000
Committee member retainersAudit $10,000; Compensation $7,500; Nominating/Gov $5,000
Committee chair retainersAudit $20,000; Compensation $15,000; Nominating/Gov $10,000
Non-executive Chair retainer$40,000 (additional)
2024 Fees earned (Karbe)$68,125

Performance Compensation

Equity Element2024 Grants/ValuesVesting/TermsSource
Annual RSU grant (directors)10,500 RSUs; grant-date fair value $108,150 ($10.30/sh)For the program in effect until May 23, 2024, annual director grants vested on the earlier of first anniversary or next annual meeting; program was amended May 23, 2024 to increase grant sizes
Annual stock option grant (directors)Options to purchase 17,500 shares; grant-date fair value (Karbe) $121,280Same annual grant program as above; options generally one-year vest under director program described (pre-amendment terms); exercise price = fair market value at grant

Notes:

  • In May 2024, the board increased initial and annual director equity award sizes to 21,000 RSUs + 35,000 options (initial) and 10,500 RSUs + 17,500 options (annual) to align with peer medians based on Pay Governance advice .
  • Equity for directors is time-based; no performance-vested equity or scorecard metrics disclosed for directors .

Other Directorships & Interlocks

  • Current public company directorships: none disclosed for Karbe; prior boards include Aduro Biotech (2019–2020) and Arbutus Biopharma (2010–2018) .
  • Interlock: PHAT director Theodore R. Schroeder is a director at Cidara Therapeutics, where Karbe serves as CFO (potential network interlock; no PHAT-related transactions with Cidara disclosed) .

Expertise & Qualifications

  • Finance/life sciences executive with CFO/President/CEO experience at public biopharmas; prior healthcare investment banking; formal finance education (Diplom Kaufmann, WHU) .
  • Audit Committee member; the Audit Committee’s designated “financial expert” is Heidi Kunz; all committee members meet SEC/Nasdaq financial literacy requirements .

Equity Ownership

As of/MetricDetail
Beneficial ownership (Apr 7, 2025)119,500 shares (<1%) consisting of 37,500 shares held directly; 62,500 options exercisable within 60 days; and 19,500 shares issuable upon RSU vesting within 60 days
Outstanding awards (Dec 31, 2024)Options outstanding: 62,500; RSUs outstanding: 10,500
Anti-hedging/pledgingHedging and pledging prohibited for directors

Director Compensation (FY2024)

ItemAmount ($)
Fees Earned or Paid in Cash68,125
Option Awards (grant-date fair value)121,280
Stock Awards (grant-date fair value)108,150
Total297,555

Related Party & Conflicts Check

  • Related-party transactions: Proxy discloses services with PCI Pharma Services (affiliated with principal stockholder Frazier), but no transactions involving Karbe are disclosed .
  • Compensation Committee interlocks: Karbe served on PHAT’s Compensation Committee through Feb 29, 2024; no cross-board executive/comp committee interlocks involving Karbe are disclosed .

Insider Trading and Section 16 Compliance

  • Section 16(a) compliance: Company states all required filings in 2024 were timely, except one late Form 4 for director Asit Parikh; no exceptions noted for Karbe in 2024 .
  • Form 4 trading detail for Karbe not provided in the proxy; no pledging/hedging allowed under company policy .

Governance Assessment

  • Independence and committee roles: Karbe is Nasdaq-independent, serves on the Audit Committee, and previously served on Compensation and Nominating/Governance—providing broad governance exposure .
  • Engagement: The board/committees met frequently and each director attended ≥75% of meetings in FY2024; all directors attended the 2024 annual meeting .
  • Alignment: Director pay structure combines cash retainer with meaningful time-based equity; Karbe held options and RSUs with total beneficial ownership of 119,500 shares as of April 7, 2025; hedging/pledging prohibited .
  • Interlocks/conflicts: Notable network interlock with Cidara (Karbe CFO; Schroeder director), but no related-party transactions disclosed involving Karbe; Audit, Comp, and N&G committee independence affirmed .